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146 related items for PubMed ID: 33452674

  • 1. 15-Deoxy-Δ12,14 -prostaglandin J2 binds and inactivates STAT3 via covalent modification of cysteine 259 in H-Ras-transformed human breast epithelial cells.
    Kim SJ, Cho NC, Han B, Kim K, Hahn YI, Kim KP, Suh YG, Choi BY, Na HK, Surh YJ.
    FEBS Lett; 2021 Mar; 595(5):604-622. PubMed ID: 33452674
    [Abstract] [Full Text] [Related]

  • 2. 15-Deoxy-Δ12,14-prostaglandin J2 activates PI3K-Akt signaling in human breast cancer cells through covalent modification of the tumor suppressor PTEN at cysteine 136.
    Suh J, Kim DH, Kim EH, Park SA, Park JM, Jang JH, Kim SJ, Na HK, Kim ND, Kim NJ, Suh YG, Surh YJ.
    Cancer Lett; 2018 Jun 28; 424():30-45. PubMed ID: 29550515
    [Abstract] [Full Text] [Related]

  • 3. 15-Deoxy-Δ12,14-prostaglandin J2 Induces Apoptosis in Ha-ras-transformed Human Breast Epithelial Cells by Targeting IκB kinase-NF-κB Signaling.
    Na HK, Yang H, Surh YJ.
    J Cancer Prev; 2020 Jun 30; 25(2):100-110. PubMed ID: 32647651
    [Abstract] [Full Text] [Related]

  • 4. STAT3 as a Potential Target for Tumor Suppressive Effects of 15-Deoxy-Δ12,14-prostaglandin J2 in Triple Negative Breast Cancer.
    Kim SJ, Cho NC, Hahn YI, Kim SH, Fang X, Surh YJ.
    J Cancer Prev; 2021 Sep 30; 26(3):207-217. PubMed ID: 34703823
    [Abstract] [Full Text] [Related]

  • 5. Identification and Molecular Characterization of Peroxisome Proliferator-Activated Receptor δ as a Novel Target for Covalent Modification by 15-Deoxy-Δ12,14-prostaglandin J2.
    Reddy AT, Lakshmi SP, Banno A, Reddy RC.
    ACS Chem Biol; 2018 Dec 21; 13(12):3269-3278. PubMed ID: 30398845
    [Abstract] [Full Text] [Related]

  • 6. Down-regulation of hTERT expression plays an important role in 15-deoxy-Delta12,14-prostaglandin J2-induced apoptosis in cancer cells.
    Moriai M, Tsuji N, Kobayashi D, Kuribayashi K, Watanabe N.
    Int J Oncol; 2009 May 21; 34(5):1363-72. PubMed ID: 19360348
    [Abstract] [Full Text] [Related]

  • 7. Molecular basis for the direct inhibition of AP-1 DNA binding by 15-deoxy-Delta 12,14-prostaglandin J2.
    Pérez-Sala D, Cernuda-Morollón E, Cañada FJ.
    J Biol Chem; 2003 Dec 19; 278(51):51251-60. PubMed ID: 14532268
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of IL-10-induced STAT3 activation by 15-deoxy-Delta12,14-prostaglandin J2.
    Ji JD, Kim HJ, Rho YH, Choi SJ, Lee YH, Cheon HJ, Sohn J, Song GG.
    Rheumatology (Oxford); 2005 Aug 19; 44(8):983-8. PubMed ID: 15840591
    [Abstract] [Full Text] [Related]

  • 9. 15-Keto prostaglandin E2 suppresses STAT3 signaling and inhibits breast cancer cell growth and progression.
    Lee EJ, Kim SJ, Hahn YI, Yoon HJ, Han B, Kim K, Lee S, Kim KP, Suh YG, Na HK, Surh YJ.
    Redox Biol; 2019 May 19; 23():101175. PubMed ID: 31129031
    [Abstract] [Full Text] [Related]

  • 10. Possible involvement of 15-deoxy-Δ(12,14) -prostaglandin J2 in the development of leptin resistance.
    Hosoi T, Matsuzaki S, Miyahara T, Shimizu K, Hasegawa Y, Ozawa K.
    J Neurochem; 2015 May 19; 133(3):343-51. PubMed ID: 25662180
    [Abstract] [Full Text] [Related]

  • 11. 15-Deoxy-△12,14-Prostaglandin J2 Promotes Resolution of Experimentally Induced Colitis.
    Kim W, Jang JH, Zhong X, Seo H, Surh YJ.
    Front Immunol; 2021 May 19; 12():615803. PubMed ID: 33633749
    [Abstract] [Full Text] [Related]

  • 12. Curcumin interacts directly with the Cysteine 259 residue of STAT3 and induces apoptosis in H-Ras transformed human mammary epithelial cells.
    Hahn YI, Kim SJ, Choi BY, Cho KC, Bandu R, Kim KP, Kim DH, Kim W, Park JS, Han BW, Lee J, Na HK, Cha YN, Surh YJ.
    Sci Rep; 2018 Apr 23; 8(1):6409. PubMed ID: 29686295
    [Abstract] [Full Text] [Related]

  • 13. The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J2 binds to and activates H-Ras.
    Oliva JL, Pérez-Sala D, Castrillo A, Martínez N, Cañada FJ, Boscá L, Rojas JM.
    Proc Natl Acad Sci U S A; 2003 Apr 15; 100(8):4772-7. PubMed ID: 12684535
    [Abstract] [Full Text] [Related]

  • 14. Physiological and Pathological Roles of 15-Deoxy-Δ12,14-Prostaglandin J2 in the Central Nervous System and Neurological Diseases.
    Yagami T, Yamamoto Y, Koma H.
    Mol Neurobiol; 2018 Mar 15; 55(3):2227-2248. PubMed ID: 28299574
    [Abstract] [Full Text] [Related]

  • 15. Multidrug resistance-associated protein 1 mediates 15-deoxy-Δ(12,14)-prostaglandin J2-induced expression of glutamate cysteine ligase expression via Nrf2 signaling in human breast cancer cells.
    Song NY, Kim DH, Kim EH, Na HK, Kim NJ, Suh YG, Surh YJ.
    Chem Res Toxicol; 2011 Aug 15; 24(8):1231-41. PubMed ID: 21728338
    [Abstract] [Full Text] [Related]

  • 16. Targeting of epidermal growth factor receptor by cyclopentenone prostaglandin 15-Deoxy-Delta12,14-prostaglandin J2 in human oral squamous carcinoma cells.
    Siavash H, Nikitakis NG, Sauk JJ.
    Cancer Lett; 2004 Jul 28; 211(1):97-103. PubMed ID: 15194221
    [Abstract] [Full Text] [Related]

  • 17. 15-Deoxy-Δ¹²,¹⁴-prostaglandin J₂ as an electrophilic mediator.
    Shibata T.
    Biosci Biotechnol Biochem; 2015 Jul 28; 79(7):1044-9. PubMed ID: 26011133
    [Abstract] [Full Text] [Related]

  • 18. 15-deoxy-Delta12,14 prostaglandin J2 up-regulates Kruppel-like factor 4 expression independently of peroxisome proliferator-activated receptor gamma by activating the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signal transduction pathway in HT-29 colon cancer cells.
    Chen ZY, Tseng CC.
    Mol Pharmacol; 2005 Nov 28; 68(5):1203-13. PubMed ID: 16077033
    [Abstract] [Full Text] [Related]

  • 19. 15-deoxy-Δ12,14-prostaglandin J₂ induces p53 expression through Nrf2-mediated upregulation of heme oxygenase-1 in human breast cancer cells.
    Kim DH, Song NY, Kim EH, Na HK, Joe Y, Chung HT, Surh YJ.
    Free Radic Res; 2014 Sep 28; 48(9):1018-27. PubMed ID: 24568186
    [Abstract] [Full Text] [Related]

  • 20. 15-Deoxy-Δ12,14-prostaglandin J2 Inhibits Cell Migration on Renal Cell Carcinoma via Down-Regulation of Focal Adhesion Kinase Signaling.
    Yamamoto Y, Koma H, Yagami T.
    Biol Pharm Bull; 2020 Sep 28; 43(1):153-157. PubMed ID: 31902920
    [Abstract] [Full Text] [Related]

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