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Journal Abstract Search

186 related items for PubMed ID: 33453177

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  • 3. A novel, orally active CXCR1/2 receptor antagonist, Sch527123, inhibits neutrophil recruitment, mucus production, and goblet cell hyperplasia in animal models of pulmonary inflammation.
    Chapman RW, Minnicozzi M, Celly CS, Phillips JE, Kung TT, Hipkin RW, Fan X, Rindgen D, Deno G, Bond R, Gonsiorek W, Billah MM, Fine JS, Hey JA.
    J Pharmacol Exp Ther; 2007 Aug; 322(2):486-93. PubMed ID: 17496165
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  • 10. Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils: a randomized, placebo-controlled clinical trial.
    Nair P, Gaga M, Zervas E, Alagha K, Hargreave FE, O'Byrne PM, Stryszak P, Gann L, Sadeh J, Chanez P, Study Investigators.
    Clin Exp Allergy; 2012 Jul; 42(7):1097-103. PubMed ID: 22702508
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  • 12. Discovery of 2-hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5- methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobut-1-enylamino}benzamide (SCH 527123): a potent, orally bioavailable CXCR2/CXCR1 receptor antagonist.
    Dwyer MP, Yu Y, Chao J, Aki C, Chao J, Biju P, Girijavallabhan V, Rindgen D, Bond R, Mayer-Ezel R, Jakway J, Hipkin RW, Fossetta J, Gonsiorek W, Bian H, Fan X, Terminelli C, Fine J, Lundell D, Merritt JR, Rokosz LL, Kaiser B, Li G, Wang W, Stauffer T, Ozgur L, Baldwin J, Taveras AG.
    J Med Chem; 2006 Dec 28; 49(26):7603-6. PubMed ID: 17181143
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  • 13. LPS challenge in healthy subjects: an investigation of neutrophil chemotaxis mechanisms involving CXCR1 and CXCR2.
    Aul R, Patel S, Summerhill S, Kilty I, Plumb J, Singh D.
    Int Immunopharmacol; 2012 Jul 28; 13(3):225-31. PubMed ID: 22561413
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  • 14. The effects of a CXCR1/CXCR2 antagonist on neutrophil migration in mild atopic asthmatic subjects.
    Todd CM, Salter BM, Murphy DM, Watson RM, Howie KJ, Milot J, Sadeh J, Boulet LP, O'Byrne PM, Gauvreau GM.
    Pulm Pharmacol Ther; 2016 Dec 28; 41():34-39. PubMed ID: 27640067
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  • 16. Effect of CXCR2 Inhibition on Behavioral Outcomes and Pathology in Rat Model of Neuromyelitis Optica.
    Jones MV, Levy M.
    J Immunol Res; 2018 Dec 28; 2018():9034695. PubMed ID: 30648122
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  • 17. Neutrophils Induce a Novel Chemokine Receptors Repertoire During Influenza Pneumonia.
    Rudd JM, Pulavendran S, Ashar HK, Ritchey JW, Snider TA, Malayer JR, Marie M, Chow VTK, Narasaraju T.
    Front Cell Infect Microbiol; 2019 Dec 28; 9():108. PubMed ID: 31041196
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