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388 related items for PubMed ID: 33493513

  • 1. Probing the structure and function of acyl carrier proteins to unlock the strategic redesign of type II polyketide biosynthetic pathways.
    Sulpizio A, Crawford CEW, Koweek RS, Charkoudian LK.
    J Biol Chem; 2021; 296():100328. PubMed ID: 33493513
    [Abstract] [Full Text] [Related]

  • 2. Engineered Chimeras Unveil Swappable Modular Features of Fatty Acid and Polyketide Synthase Acyl Carrier Proteins.
    Cho YI, Armstrong CL, Sulpizio A, Acheampong KK, Banks KN, Bardhan O, Churchill SJ, Connolly-Sporing AE, Crawford CEW, Cruz Parrilla PL, Curtis SM, De La Ossa LM, Epstein SC, Farrehi CJ, Hamrick GS, Hillegas WJ, Kang A, Laxton OC, Ling J, Matsumura SM, Merino VM, Mukhtar SH, Shah NJ, Londergan CH, Daly CA, Kokona B, Charkoudian LK.
    Biochemistry; 2022 Feb 15; 61(4):217-227. PubMed ID: 35073057
    [Abstract] [Full Text] [Related]

  • 3. Probing the Interactions of early polyketide intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
    Evans SE, Williams C, Arthur CJ, Płoskoń E, Wattana-amorn P, Cox RJ, Crosby J, Willis CL, Simpson TJ, Crump MP.
    J Mol Biol; 2009 Jun 12; 389(3):511-28. PubMed ID: 19361520
    [Abstract] [Full Text] [Related]

  • 4. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity.
    Tang Y, Lee TS, Kobayashi S, Khosla C.
    Biochemistry; 2003 Jun 03; 42(21):6588-95. PubMed ID: 12767243
    [Abstract] [Full Text] [Related]

  • 5. How Acyl Carrier Proteins (ACPs) Direct Fatty Acid and Polyketide Biosynthesis.
    Buyachuihan L, Stegemann F, Grininger M.
    Angew Chem Int Ed Engl; 2024 Jan 22; 63(4):e202312476. PubMed ID: 37856285
    [Abstract] [Full Text] [Related]

  • 6. Prediction of inter domain interactions in modular polyketide synthases by docking and correlated mutation analysis.
    Yadav G, Anand S, Mohanty D.
    J Biomol Struct Dyn; 2013 Jan 22; 31(1):17-29. PubMed ID: 22803697
    [Abstract] [Full Text] [Related]

  • 7. The malonyl transferase activity of type II polyketide synthase acyl carrier proteins.
    Arthur CJ, Szafranska AE, Long J, Mills J, Cox RJ, Findlow SC, Simpson TJ, Crump MP, Crosby J.
    Chem Biol; 2006 Jun 22; 13(6):587-96. PubMed ID: 16793516
    [Abstract] [Full Text] [Related]

  • 8. Probing the selectivity and protein·protein interactions of a nonreducing fungal polyketide synthase using mechanism-based crosslinkers.
    Bruegger J, Haushalter RW, Vagstad AL, Shakya G, Mih N, Townsend CA, Burkart MD, Tsai SC.
    Chem Biol; 2013 Sep 19; 20(9):1135-46. PubMed ID: 23993461
    [Abstract] [Full Text] [Related]

  • 9. Heterologous Expression, Purification, and Characterization of Type II Polyketide Synthase Acyl Carrier Proteins.
    Hamrick GS, Londergan CH, Charkoudian LK.
    Methods Mol Biol; 2022 Sep 19; 2489():239-267. PubMed ID: 35524054
    [Abstract] [Full Text] [Related]

  • 10. Structure, function and dynamics in acyl carrier proteins.
    Farmer R, Thomas CM, Winn PJ.
    PLoS One; 2019 Sep 19; 14(7):e0219435. PubMed ID: 31291335
    [Abstract] [Full Text] [Related]

  • 11. Evidence for a protein-protein interaction motif on an acyl carrier protein domain from a modular polyketide synthase.
    Weissman KJ, Hong H, Popovic B, Meersman F.
    Chem Biol; 2006 Jun 19; 13(6):625-36. PubMed ID: 16793520
    [Abstract] [Full Text] [Related]

  • 12. Mechanistic analysis of a type II polyketide synthase. Role of conserved residues in the beta-ketoacyl synthase-chain length factor heterodimer.
    Dreier J, Khosla C.
    Biochemistry; 2000 Feb 29; 39(8):2088-95. PubMed ID: 10684659
    [Abstract] [Full Text] [Related]

  • 13. Biochemical characterization of a malonyl-specific acyltransferase domain of FK506 biosynthetic polyketide synthase.
    Wang YY, Bai LF, Ran XX, Jiang XH, Wu H, Zhang W, Jin MY, Li YQ, Jiang H.
    Protein Pept Lett; 2015 Feb 29; 22(1):2-7. PubMed ID: 25267255
    [Abstract] [Full Text] [Related]

  • 14. Structural basis for selectivity in a highly reducing type II polyketide synthase.
    Du D, Katsuyama Y, Horiuchi M, Fushinobu S, Chen A, Davis TD, Burkart MD, Ohnishi Y.
    Nat Chem Biol; 2020 Jul 29; 16(7):776-782. PubMed ID: 32367018
    [Abstract] [Full Text] [Related]

  • 15. Structural and Biochemical Analysis of Protein-Protein Interactions Between the Acyl-Carrier Protein and Product Template Domain.
    Barajas JF, Finzel K, Valentic TR, Shakya G, Gamarra N, Martinez D, Meier JL, Vagstad AL, Newman AG, Townsend CA, Burkart MD, Tsai SC.
    Angew Chem Int Ed Engl; 2016 Oct 10; 55(42):13005-13009. PubMed ID: 27653519
    [Abstract] [Full Text] [Related]

  • 16. Rigidifying acyl carrier protein domain in iterative type I PKS CalE8 does not affect its function.
    Lim J, Sun H, Fan JS, Hameed IF, Lescar J, Liang ZX, Yang D.
    Biophys J; 2012 Sep 05; 103(5):1037-44. PubMed ID: 23009853
    [Abstract] [Full Text] [Related]

  • 17. Catalytic self-acylation of type II polyketide synthase acyl carrier proteins.
    Hitchman TS, Crosby J, Byrom KJ, Cox RJ, Simpson TJ.
    Chem Biol; 1998 Jan 05; 5(1):35-47. PubMed ID: 9479478
    [Abstract] [Full Text] [Related]

  • 18. Structural snapshots of the minimal PKS system responsible for octaketide biosynthesis.
    Bräuer A, Zhou Q, Grammbitter GLC, Schmalhofer M, Rühl M, Kaila VRI, Bode HB, Groll M.
    Nat Chem; 2020 Aug 05; 12(8):755-763. PubMed ID: 32632186
    [Abstract] [Full Text] [Related]

  • 19. Probing the interactions of an acyl carrier protein domain from the 6-deoxyerythronolide B synthase.
    Charkoudian LK, Liu CW, Capone S, Kapur S, Cane DE, Togni A, Seebach D, Khosla C.
    Protein Sci; 2011 Jul 05; 20(7):1244-55. PubMed ID: 21563224
    [Abstract] [Full Text] [Related]

  • 20. An ACP structural switch: conformational differences between the apo and holo forms of the actinorhodin polyketide synthase acyl carrier protein.
    Evans SE, Williams C, Arthur CJ, Burston SG, Simpson TJ, Crosby J, Crump MP.
    Chembiochem; 2008 Oct 13; 9(15):2424-32. PubMed ID: 18770515
    [Abstract] [Full Text] [Related]

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