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327 related items for PubMed ID: 33517508

  • 1. Neuroprotective effects of roflumilast against quinolinic acid-induced rat model of Huntington's disease through inhibition of NF-κB mediated neuroinflammatory markers and activation of cAMP/CREB/BDNF signaling pathway.
    Saroj P, Bansal Y, Singh R, Akhtar A, Sodhi RK, Bishnoi M, Sah SP, Kuhad A.
    Inflammopharmacology; 2021 Apr; 29(2):499-511. PubMed ID: 33517508
    [Abstract] [Full Text] [Related]

  • 2. Neuroprotective effect of naringin, a flavone glycoside in quinolinic acid-induced neurotoxicity: Possible role of PPAR-γ, Bax/Bcl-2, and caspase-3.
    Cui J, Wang G, Kandhare AD, Mukherjee-Kandhare AA, Bodhankar SL.
    Food Chem Toxicol; 2018 Nov; 121():95-108. PubMed ID: 30130594
    [Abstract] [Full Text] [Related]

  • 3. Roflumilast ameliorates cognitive impairment in APP/PS1 mice via cAMP/CREB/BDNF signaling and anti-neuroinflammatory effects.
    Feng H, Wang C, He W, Wu X, Li S, Zeng Z, Wei M, He B.
    Metab Brain Dis; 2019 Apr; 34(2):583-591. PubMed ID: 30610438
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  • 4. Sertraline and venlafaxine improves motor performance and neurobehavioral deficit in quinolinic acid induced Huntington's like symptoms in rats: Possible neurotransmitters modulation.
    Gill JS, Jamwal S, Kumar P, Deshmukh R.
    Pharmacol Rep; 2017 Apr; 69(2):306-313. PubMed ID: 28178592
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  • 5. Protective Effect of Spermidine Against Excitotoxic Neuronal Death Induced by Quinolinic Acid in Rats: Possible Neurotransmitters and Neuroinflammatory Mechanism.
    Jamwal S, Singh S, Kaur N, Kumar P.
    Neurotox Res; 2015 Aug; 28(2):171-84. PubMed ID: 26078029
    [Abstract] [Full Text] [Related]

  • 6. 6-shogaol against 3-Nitropropionic acid-induced Huntington's disease in rodents: Based on molecular docking/targeting pro-inflammatory cytokines/NF-κB-BDNF-Nrf2 pathway.
    Jambi EJ, Alamri A, Afzal M, Al-Abbasi FA, Al-Qahtani SD, Almalki NAR, Bawadood AS, Alzarea SI, Sayyed N, Kazmi I.
    PLoS One; 2024 Aug; 19(7):e0305358. PubMed ID: 39008492
    [Abstract] [Full Text] [Related]

  • 7. Phosphodiestrase-1 and 4 inhibitors ameliorate liver fibrosis in rats: Modulation of cAMP/CREB/TLR4 inflammatory and fibrogenic pathways.
    Essam RM, Ahmed LA, Abdelsalam RM, El-Khatib AS.
    Life Sci; 2019 Apr 01; 222():245-254. PubMed ID: 30858122
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  • 9. Possible involvement of CREB/BDNF signaling pathway in neuroprotective effects of topiramate against methylphenidate induced apoptosis, oxidative stress and inflammation in isolated hippocampus of rats: Molecular, biochemical and histological evidences.
    Motaghinejad M, Motevalian M, Babalouei F, Abdollahi M, Heidari M, Madjd Z.
    Brain Res Bull; 2017 Jun 01; 132():82-98. PubMed ID: 28552672
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  • 11. PI3K/AKT signaling activation by roflumilast ameliorates rotenone-induced Parkinson's disease in rats.
    Farid HA, Sayed RH, El-Shamarka ME, Abdel-Salam OME, El Sayed NS.
    Inflammopharmacology; 2024 Apr 01; 32(2):1421-1437. PubMed ID: 37541971
    [Abstract] [Full Text] [Related]

  • 12. Roflumilast, a cAMP-Specific Phosphodiesterase-4 Inhibitor, Reduces Oxidative Stress and Improves Synapse Functions in Human Cortical Neurons Exposed to the Excitotoxin Quinolinic Acid.
    Bhat A, Tan V, Heng B, Lovejoy DB, Sakharkar MK, Essa MM, Chidambaram SB, Guillemin GJ.
    ACS Chem Neurosci; 2020 Dec 16; 11(24):4405-4415. PubMed ID: 33261317
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  • 14. Roflumilast and tadalafil improve learning and memory deficits in intracerebroventricular Aβ1-42 rat model of Alzheimer's disease through modulations of hippocampal cAMP/cGMP/BDNF signaling pathway.
    Hasan N, Zameer S, Najmi AK, Parvez S, Yar MS, Akhtar M.
    Pharmacol Rep; 2021 Oct 16; 73(5):1287-1302. PubMed ID: 33860460
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  • 16. Bilateral quinolinic acid-induced lipid peroxidation, decreased striatal monoamine levels and neurobehavioral deficits are ameliorated by GIP receptor agonist D-Ala2GIP in rat model of Huntington's disease.
    Verma MK, Goel R, Nandakumar K, Nemmani KVS.
    Eur J Pharmacol; 2018 Jun 05; 828():31-41. PubMed ID: 29577894
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  • 17. Curcumin confers neuroprotection against alcohol-induced hippocampal neurodegeneration via CREB-BDNF pathway in rats.
    Motaghinejad M, Motevalian M, Fatima S, Hashemi H, Gholami M.
    Biomed Pharmacother; 2017 Mar 05; 87():721-740. PubMed ID: 28095363
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  • 18. Molecular, histological and behavioral evidences for neuroprotective effects of minocycline against nicotine-induced neurodegeneration and cognition impairment: Possible role of CREB-BDNF signaling pathway.
    Motaghinejad M, Farokhi N, Motevalian M, Safari S.
    Behav Brain Res; 2020 May 27; 386():112597. PubMed ID: 32198107
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  • 20. Phosphodiesterase-4 inhibitors ameliorates cognitive deficits in deoxycorticosterone acetate induced hypertensive rats via cAMP/CREB signaling system.
    Jabaris SS, Sumathy H, Girish R, Narayanan S, Sugumar M, Saravana Babu C, Thanikachalam S, Thanikachalam M.
    Brain Res; 2015 Oct 05; 1622():279-91. PubMed ID: 26168894
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