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327 related items for PubMed ID: 33517508

  • 21. Inosine attenuates 3-nitropropionic acid-induced Huntington's disease-like symptoms in rats via the activation of the A2AR/BDNF/TrKB/ERK/CREB signaling pathway.
    El-Shamarka ME, El-Sahar AE, Saad MA, Assaf N, Sayed RH.
    Life Sci; 2022 Jul 01; 300():120569. PubMed ID: 35472453
    [Abstract] [Full Text] [Related]

  • 22. Roflumilast enhances cisplatin-sensitivity and reverses cisplatin-resistance of ovarian cancer cells via cAMP/PKA/CREB-FtMt signalling axis.
    Gong S, Chen Y, Meng F, Zhang Y, Li C, Zhang G, Huan W, Wu F.
    Cell Prolif; 2018 Oct 01; 51(5):e12474. PubMed ID: 30069985
    [Abstract] [Full Text] [Related]

  • 23. Phosphodiesterase 10 inhibition reduces striatal excitotoxicity in the quinolinic acid model of Huntington's disease.
    Giampà C, Patassini S, Borreca A, Laurenti D, Marullo F, Bernardi G, Menniti FS, Fusco FR.
    Neurobiol Dis; 2009 Jun 01; 34(3):450-6. PubMed ID: 19281846
    [Abstract] [Full Text] [Related]

  • 24. Suppressing inflammatory cascade by cyclo-oxygenase inhibitors attenuates quinolinic acid induced Huntington's disease-like alterations in rats.
    Kalonia H, Kumar A.
    Life Sci; 2011 Apr 25; 88(17-18):784-91. PubMed ID: 21362433
    [Abstract] [Full Text] [Related]

  • 25. Targeting neuro-inflammatory cytokines and oxidative stress by minocycline attenuates quinolinic-acid-induced Huntington's disease-like symptoms in rats.
    Kalonia H, Mishra J, Kumar A.
    Neurotox Res; 2012 Nov 25; 22(4):310-20. PubMed ID: 22392362
    [Abstract] [Full Text] [Related]

  • 26. PDE4 inhibitor, roflumilast protects cardiomyocytes against NO-induced apoptosis via activation of PKA and Epac dual pathways.
    Kwak HJ, Park KM, Choi HE, Chung KS, Lim HJ, Park HY.
    Cell Signal; 2008 May 25; 20(5):803-14. PubMed ID: 18276108
    [Abstract] [Full Text] [Related]

  • 27. Protective effect of montelukast against quinolinic acid/malonic acid induced neurotoxicity: possible behavioral, biochemical, mitochondrial and tumor necrosis factor-α level alterations in rats.
    Kalonia H, Kumar P, Kumar A, Nehru B.
    Neuroscience; 2010 Nov 24; 171(1):284-99. PubMed ID: 20813166
    [Abstract] [Full Text] [Related]

  • 28. Phosphodiesterase-4 Inhibitor Roflumilast Attenuates Pulmonary Air Emboli-Induced Lung Injury.
    Peng CK, Huang KL, Wu CP, Wu YK, Tzeng IS, Lan CC.
    J Surg Res; 2019 Sep 24; 241():24-30. PubMed ID: 31004869
    [Abstract] [Full Text] [Related]

  • 29. Roflumilast protects from cisplatin-induced testicular toxicity in male rats and enhances its cytotoxicity in prostate cancer cell line. Role of NF-κB-p65, cAMP/PKA and Nrf2/HO-1, NQO1 signaling.
    Abdel-Wahab BA, Walbi IA, Albarqi HA, Ali FEM, Hassanein EHM.
    Food Chem Toxicol; 2021 May 24; 151():112133. PubMed ID: 33757793
    [Abstract] [Full Text] [Related]

  • 30. Roflumilast Reduces Pathological Symptoms of Sporadic Alzheimer's Disease in Rats Produced by Intracerebroventricular Streptozotocin by Inhibiting NF-κB/BACE-1 Mediated Aβ Production in the Hippocampus and Activating the cAMP/BDNF Signalling Pathway.
    Hasan N, Zameer S, Najmi AK, Parvez S, Akhtar M.
    Neurotox Res; 2022 Apr 24; 40(2):432-448. PubMed ID: 35192144
    [Abstract] [Full Text] [Related]

  • 31. The Phosphodiesterase-4 Inhibitor Roflumilast, a Potential Treatment for the Comorbidity of Memory Loss and Depression in Alzheimer's Disease: A Preclinical Study in APP/PS1 Transgenic Mice.
    Wang H, Zhang FF, Xu Y, Fu HR, Wang XD, Wang L, Chen W, Xu XY, Gao YF, Zhang JG, Zhang HT.
    Int J Neuropsychopharmacol; 2020 Dec 10; 23(10):700-711. PubMed ID: 32645141
    [Abstract] [Full Text] [Related]

  • 32. Role of LOX/COX pathways in 3-nitropropionic acid-induced Huntington's disease-like symptoms in rats: protective effect of licofelone.
    Kumar P, Kalonia H, Kumar A.
    Br J Pharmacol; 2011 Sep 10; 164(2b):644-54. PubMed ID: 21486276
    [Abstract] [Full Text] [Related]

  • 33. Striatal modulation of cAMP-response-element-binding protein (CREB) after excitotoxic lesions: implications with neuronal vulnerability in Huntington's disease.
    Giampà C, DeMarch Z, D'Angelo V, Morello M, Martorana A, Sancesario G, Bernardi G, Fusco FR.
    Eur J Neurosci; 2006 Jan 10; 23(1):11-20. PubMed ID: 16420411
    [Abstract] [Full Text] [Related]

  • 34. Neuroprotective effect of MK-801 against intra-striatal quinolinic acid induced behavioral, oxidative stress and cellular alterations in rats.
    Kalonia H, Kumar P, Nehru B, Kumar A.
    Indian J Exp Biol; 2009 Nov 10; 47(11):880-92. PubMed ID: 20099461
    [Abstract] [Full Text] [Related]

  • 35. Neuroprotective effects of various doses of topiramate against methylphenidate-induced oxidative stress and inflammation in isolated rat amygdala: the possible role of CREB/BDNF signaling pathway.
    Motaghinejad M, Motevalian M, Falak R, Heidari M, Sharzad M, Kalantari E.
    J Neural Transm (Vienna); 2016 Dec 10; 123(12):1463-1477. PubMed ID: 27665547
    [Abstract] [Full Text] [Related]

  • 36. L-theanine prevent quinolinic acid induced motor deficit and striatal neurotoxicity: Reduction in oxido-nitrosative stress and restoration of striatal neurotransmitters level.
    Jamwal S, Singh S, Gill JS, Kumar P.
    Eur J Pharmacol; 2017 Sep 15; 811():171-179. PubMed ID: 28624333
    [Abstract] [Full Text] [Related]

  • 37. Rosiglitazone synergizes the neuroprotective effects of valproic acid against quinolinic acid-induced neurotoxicity in rats: targeting PPARγ and HDAC pathways.
    Mishra J, Chaudhary T, Kumar A.
    Neurotox Res; 2014 Aug 15; 26(2):130-51. PubMed ID: 24566814
    [Abstract] [Full Text] [Related]

  • 38. Trazodone treatment protects neuronal-like cells from inflammatory insult by inhibiting NF-κB, p38 and JNK.
    Daniele S, Da Pozzo E, Zappelli E, Martini C.
    Cell Signal; 2015 Aug 15; 27(8):1609-29. PubMed ID: 25911310
    [Abstract] [Full Text] [Related]

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