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Journal Abstract Search

123 related items for PubMed ID: 33540026

  • 21. The Effects of Prodrug Size and a Carbonyl Linker on l-Type Amino Acid Transporter 1-Targeted Cellular and Brain Uptake.
    Venteicher B, Merklin K, Ngo HX, Chien HC, Hutchinson K, Campbell J, Way H, Griffith J, Alvarado C, Chandra S, Hill E, Schlessinger A, Thomas AA.
    ChemMedChem; 2021 Mar 03; 16(5):869-880. PubMed ID: 33230949
    [Abstract] [Full Text] [Related]

  • 22. Endotoxin-induced inflammation down-regulates L-type amino acid transporter 1 (LAT1) expression at the blood-brain barrier of male rats and mice.
    Wittmann G, Mohácsik P, Balkhi MY, Gereben B, Lechan RM.
    Fluids Barriers CNS; 2015 Sep 04; 12():21. PubMed ID: 26337286
    [Abstract] [Full Text] [Related]

  • 23. L-Type amino acid transporter 1 (LAT1)-utilizing prodrugs are carrier-selective despite having low affinity for organic anion transporting polypeptides (OATPs).
    Huttunen J, Gynther M, Vellonen KS, Huttunen KM.
    Int J Pharm; 2019 Nov 25; 571():118714. PubMed ID: 31610281
    [Abstract] [Full Text] [Related]

  • 24. Large Amino Acid Transporter 1 Selective Liposomes of l-DOPA Functionalized Amphiphile for Combating Glioblastoma.
    Bhunia S, Vangala V, Bhattacharya D, Ravuri HG, Kuncha M, Chakravarty S, Sistla R, Chaudhuri A.
    Mol Pharm; 2017 Nov 06; 14(11):3834-3847. PubMed ID: 28958145
    [Abstract] [Full Text] [Related]

  • 25. Improved l-Type amino acid transporter 1 (LAT1)-mediated delivery of anti-inflammatory drugs into astrocytes and microglia with reduced prostaglandin production.
    Tampio J, Löffler S, Guillon M, Hugele A, Huttunen J, Huttunen KM.
    Int J Pharm; 2021 May 15; 601():120565. PubMed ID: 33812973
    [Abstract] [Full Text] [Related]

  • 26. The Role of Large Neutral Amino Acid Transporter (LAT1) in Cancer.
    Lu X.
    Curr Cancer Drug Targets; 2019 May 15; 19(11):863-876. PubMed ID: 31376820
    [Abstract] [Full Text] [Related]

  • 27. The L-Type Amino Acid Transporter LAT1-An Emerging Target in Cancer.
    Häfliger P, Charles RP.
    Int J Mol Sci; 2019 May 16; 20(10):. PubMed ID: 31100853
    [Abstract] [Full Text] [Related]

  • 28. Amino Acid Promoieties Alter Valproic Acid Pharmacokinetics and Enable Extended Brain Exposure.
    Gynther M, Peura L, Vernerová M, Leppänen J, Kärkkäinen J, Lehtonen M, Rautio J, Huttunen KM.
    Neurochem Res; 2016 Oct 16; 41(10):2797-2809. PubMed ID: 27412117
    [Abstract] [Full Text] [Related]

  • 29. Amino acid transporter LAT1 (SLC7A5) as a molecular target for cancer diagnosis and therapeutics.
    Kanai Y.
    Pharmacol Ther; 2022 Feb 16; 230():107964. PubMed ID: 34390745
    [Abstract] [Full Text] [Related]

  • 30. Role of l-Type Amino Acid Transporter 1 at the Inner Blood-Retinal Barrier in the Blood-to-Retina Transport of Gabapentin.
    Akanuma SI, Yamakoshi A, Sugouchi T, Kubo Y, Hartz AMS, Bauer B, Hosoya KI.
    Mol Pharm; 2018 Jun 04; 15(6):2327-2337. PubMed ID: 29688723
    [Abstract] [Full Text] [Related]

  • 31. Comparison of Experimental Strategies to Study l-Type Amino Acid Transporter 1 (LAT1) Utilization by Ligands.
    Huttunen J, Agami M, Tampio J, Montaser AB, Huttunen KM.
    Molecules; 2021 Dec 22; 27(1):. PubMed ID: 35011270
    [Abstract] [Full Text] [Related]

  • 32. Structural properties for selective and efficient l-type amino acid transporter 1 (LAT1) mediated cellular uptake.
    Kärkkäinen J, Gynther M, Kokkola T, Petsalo A, Auriola S, Lahtela-Kakkonen M, Laine K, Rautio J, Huttunen KM.
    Int J Pharm; 2018 Jun 10; 544(1):91-99. PubMed ID: 29669256
    [Abstract] [Full Text] [Related]

  • 33. Site-directed mutagenesis of rabbit LAT1 at amino acids 219 and 234.
    Boado RJ, Li JY, Pardridge WM.
    J Neurochem; 2003 Mar 10; 84(6):1322-31. PubMed ID: 12614332
    [Abstract] [Full Text] [Related]

  • 34. Functional Characterization of the Solute Carrier LAT-1 (SLC7A5/SLC2A3) in Human Brain Capillary Endothelial Cells with Rapid UPLC-MS/MS Quantification of Intracellular Isotopically Labelled L-Leucine.
    Bay C, Bajraktari-Sylejmani G, Haefeli WE, Burhenne J, Weiss J, Sauter M.
    Int J Mol Sci; 2022 Mar 26; 23(7):. PubMed ID: 35408997
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  • 39. Hemocompatible LAT1-inhibitor can induce apoptosis in cancer cells without affecting brain amino acid homeostasis.
    Markowicz-Piasecka M, Huttunen J, Montaser A, Huttunen KM.
    Apoptosis; 2020 Jun 26; 25(5-6):426-440. PubMed ID: 32405891
    [Abstract] [Full Text] [Related]

  • 40. Developmental regulation of the rabbit blood-brain barrier LAT1 large neutral amino acid transporter mRNA and protein.
    Boado RJ, Li JY, Pardridge WM.
    Pediatr Res; 2004 Apr 26; 55(4):557-60. PubMed ID: 14764922
    [Abstract] [Full Text] [Related]

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