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152 related items for PubMed ID: 33549731

  • 1. YM155 and BIRC5 downregulation induce genomic instability via autophagy-mediated ROS production and inhibition in DNA repair.
    Cheng SM, Lin TY, Chang YC, Lin IW, Leung E, Cheung CHA.
    Pharmacol Res; 2021 Apr; 166():105474. PubMed ID: 33549731
    [Abstract] [Full Text] [Related]

  • 2. YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells.
    Cheng SM, Chang YC, Liu CY, Lee JY, Chan HH, Kuo CW, Lin KY, Tsai SL, Chen SH, Li CF, Leung E, Kanwar JR, Huang CC, Chang JY, Cheung CH.
    Br J Pharmacol; 2015 Jan; 172(1):214-34. PubMed ID: 25220225
    [Abstract] [Full Text] [Related]

  • 3. YM155 sensitizes non-small cell lung cancer cells to EGFR-tyrosine kinase inhibitors through the mechanism of autophagy induction.
    Dai CH, Shu Y, Chen P, Wu JN, Zhu LH, Yuan RX, Long WG, Zhu YM, Li J.
    Biochim Biophys Acta Mol Basis Dis; 2018 Dec; 1864(12):3786-3798. PubMed ID: 30315932
    [Abstract] [Full Text] [Related]

  • 4. Autophagic HuR mRNA degradation induces survivin and MCL1 downregulation in YM155-treated human leukemia cells.
    Chiou JT, Lee YC, Huang CH, Shi YJ, Wang LJ, Chang LS.
    Toxicol Appl Pharmacol; 2020 Jan 15; 387():114857. PubMed ID: 31837377
    [Abstract] [Full Text] [Related]

  • 5. The mechanism of radiosensitization by YM155, a novel small molecule inhibitor of survivin expression, is associated with DNA damage repair.
    Hu S, Fu S, Xu X, Chen L, Xu J, Li B, Qu Y, Yu H, Lu S, Li W.
    Cell Physiol Biochem; 2015 Jan 15; 37(3):1219-30. PubMed ID: 26418254
    [Abstract] [Full Text] [Related]

  • 6. The "survivin suppressants" NSC 80467 and YM155 induce a DNA damage response.
    Glaros TG, Stockwin LH, Mullendore ME, Smith B, Morrison BL, Newton DL.
    Cancer Chemother Pharmacol; 2012 Jul 15; 70(1):207-12. PubMed ID: 22526412
    [Abstract] [Full Text] [Related]

  • 7. BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells.
    Lin TY, Chan HH, Chen SH, Sarvagalla S, Chen PS, Coumar MS, Cheng SM, Chang YC, Lin CH, Leung E, Cheung CHA.
    Autophagy; 2020 Jul 15; 16(7):1296-1313. PubMed ID: 31612776
    [Abstract] [Full Text] [Related]

  • 8. Induction of autophagy-dependent apoptosis by the survivin suppressant YM155 in prostate cancer cells.
    Wang Q, Chen Z, Diao X, Huang S.
    Cancer Lett; 2011 Mar 01; 302(1):29-36. PubMed ID: 21220185
    [Abstract] [Full Text] [Related]

  • 9. Small-molecule survivin inhibitor YM155 enhances radiosensitization in esophageal squamous cell carcinoma by the abrogation of G2 checkpoint and suppression of homologous recombination repair.
    Qin Q, Cheng H, Lu J, Zhan L, Zheng J, Cai J, Yang X, Xu L, Zhu H, Zhang C, Liu J, Ma J, Zhang X, Dai S, Sun X.
    J Hematol Oncol; 2014 Aug 20; 7():62. PubMed ID: 25139395
    [Abstract] [Full Text] [Related]

  • 10. Targeted BIRC5 silencing using YM155 causes cell death in neuroblastoma cells with low ABCB1 expression.
    Lamers F, Schild L, Koster J, Versteeg R, Caron HN, Molenaar JJ.
    Eur J Cancer; 2012 Mar 20; 48(5):763-71. PubMed ID: 22088485
    [Abstract] [Full Text] [Related]

  • 11. Commitment toward cell death by activation of autophagy with survivin inhibitor YM155 in two canine squamous cell carcinoma cell lines with high expression of survivin.
    Miyamoto R, Tani H, Ikeda T, Saima H, Tamura K, Bonkobara M.
    Res Vet Sci; 2021 Mar 20; 135():412-415. PubMed ID: 33160684
    [Abstract] [Full Text] [Related]

  • 12. YM155 induces apoptosis through downregulation of specificity protein 1 and myeloid cell leukemia-1 in human oral cancer cell lines.
    Sachita K, Yu HJ, Yun JW, Lee JS, Cho SD.
    J Oral Pathol Med; 2015 Nov 20; 44(10):785-91. PubMed ID: 25475012
    [Abstract] [Full Text] [Related]

  • 13. Therapeutic potential of sepantronium bromide YM155 in gemcitabine-resistant human urothelial carcinoma cells.
    Huang YT, Cheng CC, Lin TC, Chiu TH, Lai PC.
    Oncol Rep; 2014 Feb 20; 31(2):771-80. PubMed ID: 24297644
    [Abstract] [Full Text] [Related]

  • 14. Dual induction of apoptotic and autophagic cell death by targeting survivin in head neck squamous cell carcinoma.
    Zhang L, Zhang W, Wang YF, Liu B, Zhang WF, Zhao YF, Kulkarni AB, Sun ZJ.
    Cell Death Dis; 2015 May 28; 6(5):e1771. PubMed ID: 26018732
    [Abstract] [Full Text] [Related]

  • 15. YM155, a selective survivin suppressant, inhibits tumor spread and prolongs survival in a spontaneous metastatic model of human triple negative breast cancer.
    Yamanaka K, Nakata M, Kaneko N, Fushiki H, Kita A, Nakahara T, Koutoku H, Sasamata M.
    Int J Oncol; 2011 Sep 28; 39(3):569-75. PubMed ID: 21674125
    [Abstract] [Full Text] [Related]

  • 16. Induction of autophagy-dependent cell death by the survivin suppressant YM155 in salivary adenoid cystic carcinoma.
    Wang YF, Zhang W, He KF, Liu B, Zhang L, Zhang WF, Kulkarni AB, Zhao YF, Sun ZJ.
    Apoptosis; 2014 Apr 28; 19(4):748-58. PubMed ID: 24370995
    [Abstract] [Full Text] [Related]

  • 17. Mcl-1 downregulation by YM155 contributes to its synergistic anti-tumor activities with ABT-263.
    Tang H, Shao H, Yu C, Hou J.
    Biochem Pharmacol; 2011 Nov 01; 82(9):1066-72. PubMed ID: 21784061
    [Abstract] [Full Text] [Related]

  • 18. YM155 inhibits topoisomerase function.
    Hong M, Ren MQ, Silva J, Paul A, Wilson WD, Schroeder C, Weinberger P, Janik J, Hao Z.
    Anticancer Drugs; 2017 Feb 01; 28(2):142-152. PubMed ID: 27754993
    [Abstract] [Full Text] [Related]

  • 19. Survivin selective inhibitor YM155 induce apoptosis in SK-NEP-1 Wilms tumor cells.
    Tao YF, Lu J, Du XJ, Sun LC, Zhao X, Peng L, Cao L, Xiao PF, Pang L, Wu D, Wang N, Feng X, Li YH, Ni J, Wang J, Pan J.
    BMC Cancer; 2012 Dec 26; 12():619. PubMed ID: 23267699
    [Abstract] [Full Text] [Related]

  • 20. Significance of survivin as a prognostic factor and a therapeutic target in endometrial cancer.
    Chuwa AH, Sone K, Oda K, Ikeda Y, Fukuda T, Wada-Hiraike O, Inaba K, Makii C, Takeuchi M, Oki S, Miyasaka A, Kashiyama T, Arimoto T, Kuramoto H, Kawana K, Yano T, Osuga Y, Fujii T.
    Gynecol Oncol; 2016 Jun 26; 141(3):564-569. PubMed ID: 27079211
    [Abstract] [Full Text] [Related]

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