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Journal Abstract Search

235 related items for PubMed ID: 33554954

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  • 2. Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model.
    Pérez Ortiz JM, Mollema N, Toker N, Adamski CJ, O'Callaghan B, Duvick L, Friedrich J, Walters MA, Strasser J, Hawkinson JE, Zoghbi HY, Henzler C, Orr HT, Lagalwar S.
    Neurobiol Dis; 2018 Aug; 116():93-105. PubMed ID: 29758256
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  • 4. Spinocerebellar Ataxia Type 1: Molecular Mechanisms of Neurodegeneration and Preclinical Studies.
    Pérez Ortiz JM, Orr HT.
    Adv Exp Med Biol; 2018 Aug; 1049():135-145. PubMed ID: 29427101
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  • 7. PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in spinocerebellar ataxia type 1.
    Bondar VV, Adamski CJ, Onur TS, Tan Q, Wang L, Diaz-Garcia J, Park J, Orr HT, Botas J, Zoghbi HY.
    Hum Mol Genet; 2018 Aug 15; 27(16):2863-2873. PubMed ID: 29860311
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  • 9. Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1.
    Lee WS, Al-Ramahi I, Jeong HH, Jang Y, Lin T, Adamski CJ, Lavery LA, Rath S, Richman R, Bondar VV, Alcala E, Revelli JP, Orr HT, Liu Z, Botas J, Zoghbi HY.
    J Clin Invest; 2022 May 02; 132(9):. PubMed ID: 35499073
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  • 10. Mutant ataxin1 disrupts cerebellar development in spinocerebellar ataxia type 1.
    Edamakanti CR, Do J, Didonna A, Martina M, Opal P.
    J Clin Invest; 2018 Jun 01; 128(6):2252-2265. PubMed ID: 29533923
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  • 11. BDNF is altered in a brain-region specific manner and rescues deficits in Spinocerebellar Ataxia Type 1.
    Rosa JG, Hamel K, Soles A, Sheeler C, Borgenheimer E, Gilliat S, Sbrocco K, Ghanoum F, Handler HP, Forster C, Rainwater O, Cvetanovic M.
    Neurobiol Dis; 2023 Mar 01; 178():106023. PubMed ID: 36724861
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  • 13. Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice.
    Emamian ES, Kaytor MD, Duvick LA, Zu T, Tousey SK, Zoghbi HY, Clark HB, Orr HT.
    Neuron; 2003 May 08; 38(3):375-87. PubMed ID: 12741986
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  • 14. Ataxin-1 regulates proliferation of hippocampal neural precursors.
    Asher M, Johnson A, Zecevic B, Pease D, Cvetanovic M.
    Neuroscience; 2016 May 13; 322():54-65. PubMed ID: 26876606
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  • 16. Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1).
    Sánchez I, Balagué E, Matilla-Dueñas A.
    Hum Mol Genet; 2016 Sep 15; 25(18):4021-4040. PubMed ID: 27466200
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  • 17. Indirect Negative Effect of Mutant Ataxin-1 on Short- and Long-Term Synaptic Plasticity in Mouse Models of Spinocerebellar Ataxia Type 1.
    Shuvaev AN, Belozor OS, Mozhei OI, Shuvaev AN, Fritsler YV, Khilazheva ED, Mosyagina AI, Hirai H, Teschemacher AG, Kasparov S.
    Cells; 2022 Jul 20; 11(14):. PubMed ID: 35883691
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  • 18. ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.
    Rousseaux MWC, Tschumperlin T, Lu HC, Lackey EP, Bondar VV, Wan YW, Tan Q, Adamski CJ, Friedrich J, Twaroski K, Chen W, Tolar J, Henzler C, Sharma A, Bajić A, Lin T, Duvick L, Liu Z, Sillitoe RV, Zoghbi HY, Orr HT.
    Neuron; 2018 Mar 21; 97(6):1235-1243.e5. PubMed ID: 29526553
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  • 19. Hsp70/Hsc70 regulates the effect phosphorylation has on stabilizing ataxin-1.
    Jorgensen ND, Andresen JM, Pitt JE, Swenson MA, Zoghbi HY, Orr HT.
    J Neurochem; 2007 Sep 21; 102(6):2040-2048. PubMed ID: 17540008
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  • 20. Reduction of mutant ATXN1 rescues premature death in a conditional SCA1 mouse model.
    Orengo JP, Nitschke L, van der Heijden ME, Ciaburri NA, Orr HT, Zoghbi HY.
    JCI Insight; 2022 Apr 22; 7(8):. PubMed ID: 35290244
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