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294 related items for PubMed ID: 33561435

  • 1. TET-TDG Active DNA Demethylation at CpG and Non-CpG Sites.
    DeNizio JE, Dow BJ, Serrano JC, Ghanty U, Drohat AC, Kohli RM.
    J Mol Biol; 2021 Apr 16; 433(8):166877. PubMed ID: 33561435
    [Abstract] [Full Text] [Related]

  • 2. Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites.
    Maiti A, Drohat AC.
    J Biol Chem; 2011 Oct 14; 286(41):35334-35338. PubMed ID: 21862836
    [Abstract] [Full Text] [Related]

  • 3. TET2-mediated 5-hydroxymethylcytosine induces genetic instability and mutagenesis.
    Mahfoudhi E, Talhaoui I, Cabagnols X, Della Valle V, Secardin L, Rameau P, Bernard OA, Ishchenko AA, Abbes S, Vainchenker W, Saparbaev M, Plo I.
    DNA Repair (Amst); 2016 Jul 14; 43():78-88. PubMed ID: 27289557
    [Abstract] [Full Text] [Related]

  • 4. Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase.
    Raiber EA, Beraldi D, Ficz G, Burgess HE, Branco MR, Murat P, Oxley D, Booth MJ, Reik W, Balasubramanian S.
    Genome Biol; 2012 Aug 17; 13(8):R69. PubMed ID: 22902005
    [Abstract] [Full Text] [Related]

  • 5. Direct and Base Excision Repair-Mediated Regulation of a GC-Rich cis-Element in Response to 5-Formylcytosine and 5-Carboxycytosine.
    Müller N, Ponkkonen E, Carell T, Khobta A.
    Int J Mol Sci; 2021 Oct 13; 22(20):. PubMed ID: 34681690
    [Abstract] [Full Text] [Related]

  • 6. Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.
    He YF, Li BZ, Li Z, Liu P, Wang Y, Tang Q, Ding J, Jia Y, Chen Z, Li L, Sun Y, Li X, Dai Q, Song CX, Zhang K, He C, Xu GL.
    Science; 2011 Sep 02; 333(6047):1303-7. PubMed ID: 21817016
    [Abstract] [Full Text] [Related]

  • 7. Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism.
    Weber AR, Krawczyk C, Robertson AB, Kuśnierczyk A, Vågbø CB, Schuermann D, Klungland A, Schär P.
    Nat Commun; 2016 Mar 02; 7():10806. PubMed ID: 26932196
    [Abstract] [Full Text] [Related]

  • 8. Functional impacts of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine at a single hemi-modified CpG dinucleotide in a gene promoter.
    Kitsera N, Allgayer J, Parsa E, Geier N, Rossa M, Carell T, Khobta A.
    Nucleic Acids Res; 2017 Nov 02; 45(19):11033-11042. PubMed ID: 28977475
    [Abstract] [Full Text] [Related]

  • 9. Epigenetic modifications in DNA could mimic oxidative DNA damage: A double-edged sword.
    Ito S, Kuraoka I.
    DNA Repair (Amst); 2015 Aug 02; 32():52-57. PubMed ID: 25956859
    [Abstract] [Full Text] [Related]

  • 10. Excision of 5-Carboxylcytosine by Thymine DNA Glycosylase.
    Pidugu LS, Dai Q, Malik SS, Pozharski E, Drohat AC.
    J Am Chem Soc; 2019 Nov 27; 141(47):18851-18861. PubMed ID: 31693361
    [Abstract] [Full Text] [Related]

  • 11. Role of base excision repair in maintaining the genetic and epigenetic integrity of CpG sites.
    Bellacosa A, Drohat AC.
    DNA Repair (Amst); 2015 Aug 27; 32():33-42. PubMed ID: 26021671
    [Abstract] [Full Text] [Related]

  • 12. Structural Basis for Excision of 5-Formylcytosine by Thymine DNA Glycosylase.
    Pidugu LS, Flowers JW, Coey CT, Pozharski E, Greenberg MM, Drohat AC.
    Biochemistry; 2016 Nov 15; 55(45):6205-6208. PubMed ID: 27805810
    [Abstract] [Full Text] [Related]

  • 13. Divergent mechanisms for enzymatic excision of 5-formylcytosine and 5-carboxylcytosine from DNA.
    Maiti A, Michelson AZ, Armwood CJ, Lee JK, Drohat AC.
    J Am Chem Soc; 2013 Oct 23; 135(42):15813-22. PubMed ID: 24063363
    [Abstract] [Full Text] [Related]

  • 14. Roles of TET and TDG in DNA demethylation in proliferating and non-proliferating immune cells.
    Onodera A, González-Avalos E, Lio CJ, Georges RO, Bellacosa A, Nakayama T, Rao A.
    Genome Biol; 2021 Jun 22; 22(1):186. PubMed ID: 34158086
    [Abstract] [Full Text] [Related]

  • 15. Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics.
    Shen L, Wu H, Diep D, Yamaguchi S, D'Alessio AC, Fung HL, Zhang K, Zhang Y.
    Cell; 2013 Apr 25; 153(3):692-706. PubMed ID: 23602152
    [Abstract] [Full Text] [Related]

  • 16. Screening of glycosylase activity on oxidative derivatives of methylcytosine: Pedobacter heparinus SMUG2 as a formylcytosine- and carboxylcytosine-DNA glycosylase.
    Chang C, Yang Y, Li J, Park SH, Fang GC, Liang C, Cao W.
    DNA Repair (Amst); 2022 Nov 25; 119():103408. PubMed ID: 36179537
    [Abstract] [Full Text] [Related]

  • 17. Maintenance DNA Methyltransferase Activity in the Presence of Oxidized Forms of 5-Methylcytosine: Structural Basis for Ten Eleven Translocation-Mediated DNA Demethylation.
    Seiler CL, Fernandez J, Koerperich Z, Andersen MP, Kotandeniya D, Nguyen ME, Sham YY, Tretyakova NY.
    Biochemistry; 2018 Oct 23; 57(42):6061-6069. PubMed ID: 30230311
    [Abstract] [Full Text] [Related]

  • 18. Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA.
    Maiti A, Noon MS, MacKerell AD, Pozharski E, Drohat AC.
    Proc Natl Acad Sci U S A; 2012 May 22; 109(21):8091-6. PubMed ID: 22573813
    [Abstract] [Full Text] [Related]

  • 19. PRDM14 promotes active DNA demethylation through the ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells.
    Okashita N, Kumaki Y, Ebi K, Nishi M, Okamoto Y, Nakayama M, Hashimoto S, Nakamura T, Sugasawa K, Kojima N, Takada T, Okano M, Seki Y.
    Development; 2014 Jan 22; 141(2):269-80. PubMed ID: 24335252
    [Abstract] [Full Text] [Related]

  • 20. Defining the impact of sumoylation on substrate binding and catalysis by thymine DNA glycosylase.
    Coey CT, Drohat AC.
    Nucleic Acids Res; 2018 Jun 01; 46(10):5159-5170. PubMed ID: 29660017
    [Abstract] [Full Text] [Related]

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