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Journal Abstract Search

266 related items for PubMed ID: 33576714

  • 1. Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity.
    Chen S, Wu Q, Li X, Li D, Mei N, Ning B, Puig M, Ren Z, Tolleson WH, Guo L.
    J Environ Sci Health C Toxicol Carcinog; 2021; 39(1):68-86. PubMed ID: 33576714
    [Abstract] [Full Text] [Related]

  • 2. Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity.
    Xuan J, Chen S, Ning B, Tolleson WH, Guo L.
    Chem Biol Interact; 2016 Aug 05; 255():63-73. PubMed ID: 26477383
    [Abstract] [Full Text] [Related]

  • 3. The role of hepatic cytochrome P450s in the cytotoxicity of dronedarone.
    Chen S, Wu Q, Ning B, Bryant M, Guo L.
    Arch Toxicol; 2018 Jun 05; 92(6):1969-1981. PubMed ID: 29616291
    [Abstract] [Full Text] [Related]

  • 4. The involvement of hepatic cytochrome P450s in the cytotoxicity of lapatinib.
    Chen S, Li X, Li Y, He X, Bryant M, Qin X, Li F, Seo JE, Guo X, Mei N, Guo L.
    Toxicol Sci; 2023 Dec 21; 197(1):69-78. PubMed ID: 37788138
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  • 6. Study of the roles of cytochrome P450 (CYPs) in the metabolism and cytotoxicity of perhexiline.
    Ren Z, Chen S, Qin X, Li F, Guo L.
    Arch Toxicol; 2022 Dec 21; 96(12):3219-3231. PubMed ID: 36083301
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  • 9. Comparison of the substrate specificities of human liver cytochrome P450s 2C9 and 2C18: application to the design of a specific substrate of CYP 2C18.
    Minoletti C, Dijols S, Dansette PM, Mansuy D.
    Biochemistry; 1999 Jun 15; 38(24):7828-36. PubMed ID: 10387023
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  • 10. Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.
    Marill J, Cresteil T, Lanotte M, Chabot GG.
    Mol Pharmacol; 2000 Dec 15; 58(6):1341-8. PubMed ID: 11093772
    [Abstract] [Full Text] [Related]

  • 11. Ellipticine oxidation and DNA adduct formation in human hepatocytes is catalyzed by human cytochromes P450 and enhanced by cytochrome b5.
    Stiborová M, Poljaková J, Martínková E, Ulrichová J, Simánek V, Dvořák Z, Frei E.
    Toxicology; 2012 Dec 16; 302(2-3):233-41. PubMed ID: 22917556
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  • 12. Human cytochrome P450s involved in the metabolism of 9-cis- and 13-cis-retinoic acids.
    Marill J, Capron CC, Idres N, Chabot GG.
    Biochem Pharmacol; 2002 Mar 01; 63(5):933-43. PubMed ID: 11911845
    [Abstract] [Full Text] [Related]

  • 13. Arachidonic acid metabolism by human cytochrome P450s 2C8, 2C9, 2E1, and 1A2: regioselective oxygenation and evidence for a role for CYP2C enzymes in arachidonic acid epoxygenation in human liver microsomes.
    Rifkind AB, Lee C, Chang TK, Waxman DJ.
    Arch Biochem Biophys; 1995 Jul 10; 320(2):380-9. PubMed ID: 7625847
    [Abstract] [Full Text] [Related]

  • 14. CYP3A4 is a major isoform responsible for oxidation of 7-hydroxy-Delta(8)-tetrahydrocannabinol to 7-oxo-delta(8)-tetrahydrocannabinol in human liver microsomes.
    Matsunaga T, Kishi N, Higuchi S, Watanabe K, Ohshima T, Yamamoto I.
    Drug Metab Dispos; 2000 Nov 10; 28(11):1291-6. PubMed ID: 11038155
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  • 15. Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells.
    Rodríguez-Antona C, Donato MT, Boobis A, Edwards RJ, Watts PS, Castell JV, Gómez-Lechón MJ.
    Xenobiotica; 2002 Jun 10; 32(6):505-20. PubMed ID: 12160483
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  • 16. Assessment of a dry extract from milk thistle (Silybum marianum) for interference with human liver cytochrome-P450 activities.
    Doehmer J, Weiss G, McGregor GP, Appel K.
    Toxicol In Vitro; 2011 Feb 10; 25(1):21-7. PubMed ID: 20828605
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  • 17. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM, Murray M.
    J Pharmacol Exp Ther; 1997 Feb 10; 280(2):966-73. PubMed ID: 9023313
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  • 18. Comparative cytochrome P450 -1A1, -2A6, -2B6, -2C, -2D6, -2E1, -3A5 and -4B1 expressions in human larynx tissue analysed at mRNA level.
    Sarikaya D, Bilgen C, Kamataki T, Topcu Z.
    Biopharm Drug Dispos; 2006 Nov 10; 27(8):353-9. PubMed ID: 16894644
    [Abstract] [Full Text] [Related]

  • 19. The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers.
    Šulc M, Indra R, Moserová M, Schmeiser HH, Frei E, Arlt VM, Stiborová M.
    Environ Mol Mutagen; 2016 Apr 10; 57(3):229-35. PubMed ID: 26919089
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  • 20. The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity.
    Wu Q, Ning B, Xuan J, Ren Z, Guo L, Bryant MS.
    Toxicol Lett; 2016 Jun 24; 253():55-62. PubMed ID: 27113703
    [Abstract] [Full Text] [Related]

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