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142 related items for PubMed ID: 33631143

  • 1. Loss of postprandial insulin clearance control by Insulin-degrading enzyme drives dysmetabolism traits.
    Borges DO, Patarrão RS, Ribeiro RT, de Oliveira RM, Duarte N, Belew GD, Martins M, Andrade R, Costa J, Correia I, Boavida JM, Duarte R, Gardete-Correia L, Medina JL, Raposo JF, Jones JG, Penha-Gonçalves C, Macedo MP.
    Metabolism; 2021 May; 118():154735. PubMed ID: 33631143
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  • 4. Liver-specific ablation of insulin-degrading enzyme causes hepatic insulin resistance and glucose intolerance, without affecting insulin clearance in mice.
    Villa-Pérez P, Merino B, Fernández-Díaz CM, Cidad P, Lobatón CD, Moreno A, Muturi HT, Ghadieh HE, Najjar SM, Leissring MA, Cózar-Castellano I, Perdomo G.
    Metabolism; 2018 Nov; 88():1-11. PubMed ID: 30098324
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  • 5. Hyperinsulinemia caused by dexamethasone treatment is associated with reduced insulin clearance and lower hepatic activity of insulin-degrading enzyme.
    Protzek AO, Rezende LF, Costa-Júnior JM, Ferreira SM, Cappelli AP, de Paula FM, de Souza JC, Kurauti MA, Carneiro EM, Rafacho A, Boschero AC.
    J Steroid Biochem Mol Biol; 2016 Jan; 155(Pt A):1-8. PubMed ID: 26386462
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  • 7. Deletion of insulin-degrading enzyme elicits antipodal, age-dependent effects on glucose and insulin tolerance.
    Abdul-Hay SO, Kang D, McBride M, Li L, Zhao J, Leissring MA.
    PLoS One; 2011 Jan; 6(6):e20818. PubMed ID: 21695259
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  • 8. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo.
    Farris W, Mansourian S, Chang Y, Lindsley L, Eckman EA, Frosch MP, Eckman CB, Tanzi RE, Selkoe DJ, Guenette S.
    Proc Natl Acad Sci U S A; 2003 Apr 01; 100(7):4162-7. PubMed ID: 12634421
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  • 9. Regulation of insulin degrading enzyme activity by obesity-associated factors and pioglitazone in liver of diet-induced obese mice.
    Wei X, Ke B, Zhao Z, Ye X, Gao Z, Ye J.
    PLoS One; 2014 Apr 01; 9(4):e95399. PubMed ID: 24740421
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  • 10. Reduced insulin sensitivity and increased β/α cell mass is associated with reduced hepatic insulin-degrading enzyme activity in pregnant rats.
    Taschetto APD, Zimath PL, Silvério R, Dos Santos C, Boschero AC, Dos Santos GJ, Rafacho A.
    Life Sci; 2021 Jul 15; 277():119509. PubMed ID: 33865877
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  • 11. Insulin-degrading enzyme inhibition increases the unfolded protein response and favours lipid accumulation in the liver.
    Andres M, Hennuyer N, Zibar K, Bicharel-Leconte M, Duplan I, Enée E, Vallez E, Herledan A, Loyens A, Staels B, Deprez B, van Endert P, Deprez-Poulain R, Lancel S.
    Br J Pharmacol; 2024 Oct 15; 181(19):3610-3626. PubMed ID: 38812293
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  • 13. Polymorphisms within insulin-degrading enzyme (IDE) gene determine insulin metabolism and risk of type 2 diabetes.
    Rudovich N, Pivovarova O, Fisher E, Fischer-Rosinsky A, Spranger J, Möhlig M, Schulze MB, Boeing H, Pfeiffer AF.
    J Mol Med (Berl); 2009 Nov 15; 87(11):1145-51. PubMed ID: 19809796
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  • 14. Interleukin-6 increases the expression and activity of insulin-degrading enzyme.
    Kurauti MA, Costa-Júnior JM, Ferreira SM, Santos GJ, Sponton CHG, Carneiro EM, Telles GD, Chacon-Mikahil MPT, Cavaglieri CR, Rezende LF, Boschero AC.
    Sci Rep; 2017 Apr 21; 7():46750. PubMed ID: 28429777
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  • 15. Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones.
    Maianti JP, McFedries A, Foda ZH, Kleiner RE, Du XQ, Leissring MA, Tang WJ, Charron MJ, Seeliger MA, Saghatelian A, Liu DR.
    Nature; 2014 Jul 03; 511(7507):94-8. PubMed ID: 24847884
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  • 16. Long-Term High-Fat Diet Decreases Renal Insulin-Degrading Enzyme Expression and Function by Inhibiting the PPARγ Pathway.
    Su Q, Huang J, Chen X, Wang Y, Shao M, Yan H, Chen C, Ren H, Zhang F, Ni Y, Jose PA, Zhong J, Yang J.
    Mol Nutr Food Res; 2023 Apr 03; 67(7):e2200589. PubMed ID: 36726048
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  • 17. Reduced Insulin Clearance and Insulin-Degrading Enzyme Activity Contribute to Hyperinsulinemia in African Americans.
    Fosam A, Sikder S, Abel BS, Tella SH, Walter MF, Mari A, Muniyappa R.
    J Clin Endocrinol Metab; 2020 Apr 01; 105(4):e1835-46. PubMed ID: 32052016
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  • 18. Prediabetes blunts DPP4 genetic control of postprandial glycaemia and insulin secretion.
    Patarrão RS, Duarte N, Coelho I, Ward J, Ribeiro RT, Meneses MJ, Andrade R, Costa J, Correia I, Boavida JM, Duarte R, Gardete-Correia L, Medina JL, Pell J, Petrie J, Raposo JF, Macedo MP, Penha-Gonçalves C.
    Diabetologia; 2022 May 01; 65(5):861-871. PubMed ID: 35190847
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  • 19. Green tea polyphenol epigallocatechin-3-gallate ameliorates insulin resistance in non-alcoholic fatty liver disease mice.
    Gan L, Meng ZJ, Xiong RB, Guo JQ, Lu XC, Zheng ZW, Deng YP, Luo BD, Zou F, Li H.
    Acta Pharmacol Sin; 2015 May 01; 36(5):597-605. PubMed ID: 25891086
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  • 20. Short-Term Calorie Restriction Maintains Plasma Insulin Concentrations along with a Reduction in Hepatic Insulin-Degrading Enzyme Levels in db/db Mice.
    Nonaka Y, Takeda R, Kano Y, Hoshino D.
    Nutrients; 2021 Apr 03; 13(4):. PubMed ID: 33916828
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