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Journal Abstract Search

170 related items for PubMed ID: 33657187

  • 1. Sleep-related hypermotor epilepsy associated mutations uncover important kinetic roles of α4β2- nicotinic acetylcholine receptor intracellular structures.
    Weltzin MM, George AA, Lukas RJ, Whiteaker P.
    PLoS One; 2021; 16(3):e0247825. PubMed ID: 33657187
    [Abstract] [Full Text] [Related]

  • 2. Distinctive effects of nicotinic receptor intracellular-loop mutations associated with nocturnal frontal lobe epilepsy.
    Weltzin MM, Lindstrom JM, Lukas RJ, Whiteaker P.
    Neuropharmacology; 2016 Mar; 102():158-73. PubMed ID: 26561946
    [Abstract] [Full Text] [Related]

  • 3. Distinctive single-channel properties of α4β2-nicotinic acetylcholine receptor isoforms.
    Weltzin MM, George AA, Lukas RJ, Whiteaker P.
    PLoS One; 2019 Mar; 14(3):e0213143. PubMed ID: 30845161
    [Abstract] [Full Text] [Related]

  • 4. Differential α4(+)/(-)β2 Agonist-binding Site Contributions to α4β2 Nicotinic Acetylcholine Receptor Function within and between Isoforms.
    Lucero LM, Weltzin MM, Eaton JB, Cooper JF, Lindstrom JM, Lukas RJ, Whiteaker P.
    J Biol Chem; 2016 Jan 29; 291(5):2444-59. PubMed ID: 26644472
    [Abstract] [Full Text] [Related]

  • 5. The unique α4+/-α4 agonist binding site in (α4)3(β2)2 subtype nicotinic acetylcholine receptors permits differential agonist desensitization pharmacology versus the (α4)2(β2)3 subtype.
    Eaton JB, Lucero LM, Stratton H, Chang Y, Cooper JF, Lindstrom JM, Lukas RJ, Whiteaker P.
    J Pharmacol Exp Ther; 2014 Jan 29; 348(1):46-58. PubMed ID: 24190916
    [Abstract] [Full Text] [Related]

  • 6. Mutation Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Reduces Low-Sensitivity α4β2, and Increases α5α4β2, Nicotinic Receptor Surface Expression.
    Nichols WA, Henderson BJ, Marotta CB, Yu CY, Richards C, Dougherty DA, Lester HA, Cohen BN.
    PLoS One; 2016 Jan 29; 11(6):e0158032. PubMed ID: 27336596
    [Abstract] [Full Text] [Related]

  • 7. Revisiting autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) mutations in the nicotinic acetylcholine receptor reveal an increase in efficacy regardless of stochiometry.
    Indurthi DC, Qudah T, Liao VW, Ahring PK, Lewis TM, Balle T, Chebib M, Absalom NL.
    Pharmacol Res; 2019 Jan 29; 139():215-227. PubMed ID: 30472464
    [Abstract] [Full Text] [Related]

  • 8. Additional acetylcholine (ACh) binding site at alpha4/alpha4 interface of (alpha4beta2)2alpha4 nicotinic receptor influences agonist sensitivity.
    Mazzaferro S, Benallegue N, Carbone A, Gasparri F, Vijayan R, Biggin PC, Moroni M, Bermudez I.
    J Biol Chem; 2011 Sep 02; 286(35):31043-31054. PubMed ID: 21757735
    [Abstract] [Full Text] [Related]

  • 9. Discovery of an intrasubunit nicotinic acetylcholine receptor-binding site for the positive allosteric modulator Br-PBTC.
    Norleans J, Wang J, Kuryatov A, Leffler A, Doebelin C, Kamenecka TM, Lindstrom J.
    J Biol Chem; 2019 Aug 09; 294(32):12132-12145. PubMed ID: 31221718
    [Abstract] [Full Text] [Related]

  • 10. The additional ACh binding site at the α4(+)/α4(-) interface of the (α4β2)2α4 nicotinic ACh receptor contributes to desensitization.
    Benallegue N, Mazzaferro S, Alcaino C, Bermudez I.
    Br J Pharmacol; 2013 Sep 09; 170(2):304-16. PubMed ID: 23742319
    [Abstract] [Full Text] [Related]

  • 11. Roles of nicotinic acetylcholine receptor β subunit cytoplasmic loops in acute desensitization and single-channel features.
    Liu Q, Kuo YP, Shen J, Lukas RJ, Wu J.
    Neuroscience; 2015 Mar 19; 289():315-23. PubMed ID: 25536046
    [Abstract] [Full Text] [Related]

  • 12. Unraveling amino acid residues critical for allosteric potentiation of (α4)3(β2)2-type nicotinic acetylcholine receptor responses.
    Wang ZJ, Deba F, Mohamed TS, Chiara DC, Ramos K, Hamouda AK.
    J Biol Chem; 2017 Jun 16; 292(24):9988-10001. PubMed ID: 28446611
    [Abstract] [Full Text] [Related]

  • 13. Roles of nicotinic acetylcholine receptor beta subunits in function of human alpha4-containing nicotinic receptors.
    Wu J, Liu Q, Yu K, Hu J, Kuo YP, Segerberg M, St John PA, Lukas RJ.
    J Physiol; 2006 Oct 01; 576(Pt 1):103-18. PubMed ID: 16825297
    [Abstract] [Full Text] [Related]

  • 14. Photolabeling a Nicotinic Acetylcholine Receptor (nAChR) with an (α4)3(β2)2 nAChR-Selective Positive Allosteric Modulator.
    Hamouda AK, Deba F, Wang ZJ, Cohen JB.
    Mol Pharmacol; 2016 May 01; 89(5):575-84. PubMed ID: 26976945
    [Abstract] [Full Text] [Related]

  • 15. Non-equivalent ligand selectivity of agonist sites in (α4β2)2α4 nicotinic acetylcholine receptors: a key determinant of agonist efficacy.
    Mazzaferro S, Gasparri F, New K, Alcaino C, Faundez M, Iturriaga Vasquez P, Vijayan R, Biggin PC, Bermudez I.
    J Biol Chem; 2014 Aug 01; 289(31):21795-806. PubMed ID: 24936069
    [Abstract] [Full Text] [Related]

  • 16. A signal peptide missense mutation associated with nicotine dependence alters α2*-nicotinic acetylcholine receptor function.
    Dash B, Lukas RJ, Li MD.
    Neuropharmacology; 2014 Apr 01; 79():715-25. PubMed ID: 24467848
    [Abstract] [Full Text] [Related]

  • 17. alpha4beta2 nicotinic receptors with high and low acetylcholine sensitivity: pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine.
    Moroni M, Zwart R, Sher E, Cassels BK, Bermudez I.
    Mol Pharmacol; 2006 Aug 01; 70(2):755-68. PubMed ID: 16720757
    [Abstract] [Full Text] [Related]

  • 18. α4β2 Nicotinic Acetylcholine Receptors: RELATIONSHIPS BETWEEN SUBUNIT STOICHIOMETRY AND FUNCTION AT THE SINGLE CHANNEL LEVEL.
    Mazzaferro S, Bermudez I, Sine SM.
    J Biol Chem; 2017 Feb 17; 292(7):2729-2740. PubMed ID: 28031459
    [Abstract] [Full Text] [Related]

  • 19. Engineered α4β2 nicotinic acetylcholine receptors as models for measuring agonist binding and effect at the orthosteric low-affinity α4-α4 interface.
    Ahring PK, Olsen JA, Nielsen EØ, Peters D, Pedersen MH, Rohde LA, Kastrup JS, Shahsavar A, Indurthi DC, Chebib M, Gajhede M, Balle T.
    Neuropharmacology; 2015 May 17; 92():135-45. PubMed ID: 25595102
    [Abstract] [Full Text] [Related]

  • 20. Mutations linked to autosomal dominant nocturnal frontal lobe epilepsy affect allosteric Ca2+ activation of the alpha 4 beta 2 nicotinic acetylcholine receptor.
    Rodrigues-Pinguet NO, Pinguet TJ, Figl A, Lester HA, Cohen BN.
    Mol Pharmacol; 2005 Aug 17; 68(2):487-501. PubMed ID: 15901849
    [Abstract] [Full Text] [Related]

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