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181 related items for PubMed ID: 33660934

  • 1. Impact of carboxylesterase 1 genetic polymorphism on trandolapril activation in human liver and the pharmacokinetics and pharmacodynamics in healthy volunteers.
    Wang X, Her L, Xiao J, Shi J, Wu AH, Bleske BE, Zhu HJ.
    Clin Transl Sci; 2021 Jul; 14(4):1380-1389. PubMed ID: 33660934
    [Abstract] [Full Text] [Related]

  • 2. Effect of CES1 genetic variation on enalapril steady-state pharmacokinetics and pharmacodynamics in healthy subjects.
    Her LH, Wang X, Shi J, Choi HJ, Jung SM, Smith LS, Wu AH, Bleske BE, Zhu HJ.
    Br J Clin Pharmacol; 2021 Dec; 87(12):4691-4700. PubMed ID: 33963573
    [Abstract] [Full Text] [Related]

  • 3. CES1P1 variant -816A>C is not associated with hepatic carboxylesterase 1 expression and activity or antihypertensive effect of trandolapril.
    Zhu HJ, Langaee TY, Gong Y, Wang X, Pepine CJ, Cooper-DeHoff RM, Johnson JA, Markowitz JS.
    Eur J Clin Pharmacol; 2016 Jun; 72(6):681-7. PubMed ID: 26915813
    [Abstract] [Full Text] [Related]

  • 4. Pharmacokinetics, Pharmacodynamics, and Tolerability of Single and Multiple Doses of Trandolapril, an Effective Angiotensin-Converting Enzyme Inhibitor, in Healthy Chinese Subjects.
    Li X, Liu C, Wu M, Zhang H, Sun Y, Cheng L, Chen H, Liu C, Yang L, Zhang Q, Cao Y, Gu J, Ding Y.
    Eur J Drug Metab Pharmacokinet; 2016 Aug; 41(4):373-84. PubMed ID: 25864194
    [Abstract] [Full Text] [Related]

  • 5. CES1 genetic variation affects the activation of angiotensin-converting enzyme inhibitors.
    Wang X, Wang G, Shi J, Aa J, Comas R, Liang Y, Zhu HJ.
    Pharmacogenomics J; 2016 Jun; 16(3):220-30. PubMed ID: 26076923
    [Abstract] [Full Text] [Related]

  • 6. Dabigatran etexilate activation is affected by the CES1 genetic polymorphism G143E (rs71647871) and gender.
    Shi J, Wang X, Nguyen JH, Bleske BE, Liang Y, Liu L, Zhu HJ.
    Biochem Pharmacol; 2016 Nov 01; 119():76-84. PubMed ID: 27614009
    [Abstract] [Full Text] [Related]

  • 7. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation.
    Shi J, Wang X, Nguyen J, Wu AH, Bleske BE, Zhu HJ.
    Drug Metab Dispos; 2016 Apr 01; 44(4):554-9. PubMed ID: 26817948
    [Abstract] [Full Text] [Related]

  • 8. Effect of carboxylesterase 1 c.428G > A single nucleotide variation on the pharmacokinetics of quinapril and enalapril.
    Tarkiainen EK, Tornio A, Holmberg MT, Launiainen T, Neuvonen PJ, Backman JT, Niemi M.
    Br J Clin Pharmacol; 2015 Nov 01; 80(5):1131-8. PubMed ID: 25919042
    [Abstract] [Full Text] [Related]

  • 9. Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril.
    Zhu HJ, Appel DI, Johnson JA, Chavin KD, Markowitz JS.
    Biochem Pharmacol; 2009 Apr 01; 77(7):1266-72. PubMed ID: 19185566
    [Abstract] [Full Text] [Related]

  • 10. Trandolapril: pharmacokinetics of single oral doses in healthy male volunteers.
    Lenfant B, Mouren M, Bryce T, De Lauture D, Strauch G.
    J Cardiovasc Pharmacol; 1994 Apr 01; 23 Suppl 4():S38-43. PubMed ID: 7527100
    [Abstract] [Full Text] [Related]

  • 11. Association of Oseltamivir Activation with Gender and Carboxylesterase 1 Genetic Polymorphisms.
    Shi J, Wang X, Eyler RF, Liang Y, Liu L, Mueller BA, Zhu HJ.
    Basic Clin Pharmacol Toxicol; 2016 Dec 01; 119(6):555-561. PubMed ID: 27228223
    [Abstract] [Full Text] [Related]

  • 12. In vitro drug metabolism by human carboxylesterase 1: focus on angiotensin-converting enzyme inhibitors.
    Thomsen R, Rasmussen HB, Linnet K, INDICES Consortium.
    Drug Metab Dispos; 2014 Jan 01; 42(1):126-33. PubMed ID: 24141856
    [Abstract] [Full Text] [Related]

  • 13. The Pharmacokinetics of Enalapril in Relation to CES1 Genotype in Healthy Danish Volunteers.
    Stage C, Jürgens G, Guski LS, Thomsen R, Bjerre D, Ferrero-Miliani L, Lyauk YK, Rasmussen HB, Dalhoff K, INDICES Consortium (for members of this consortium-see Supplementum).
    Basic Clin Pharmacol Toxicol; 2017 Dec 01; 121(6):487-492. PubMed ID: 28639420
    [Abstract] [Full Text] [Related]

  • 14. Pharmacokinetics and pharmacodynamics of trandolapril after repeated administration of 2 mg to patients with chronic renal failure and healthy control subjects.
    Danielson B, Querin S, LaRochelle P, Sultan E, Mouren M, Bryce T, Stepniewski JP, Lenfant B.
    J Cardiovasc Pharmacol; 1994 Dec 01; 23 Suppl 4():S50-9. PubMed ID: 7527102
    [Abstract] [Full Text] [Related]

  • 15. Carboxylesterase 1 and Precision Pharmacotherapy: Pharmacogenetics and Nongenetic Regulators.
    Her L, Zhu HJ.
    Drug Metab Dispos; 2020 Mar 01; 48(3):230-244. PubMed ID: 31871135
    [Abstract] [Full Text] [Related]

  • 16. Contributions of Cathepsin A and Carboxylesterase 1 to the Hydrolysis of Tenofovir Alafenamide in the Human Liver, and the Effect of CES1 Genetic Variation on Tenofovir Alafenamide Hydrolysis.
    Li J, Shi J, Xiao J, Tran L, Wang X, Zhu HJ.
    Drug Metab Dispos; 2022 Mar 01; 50(3):243-248. PubMed ID: 34933885
    [Abstract] [Full Text] [Related]

  • 17. Pharmacokinetics and pharmacodynamics of trandolapril after repeated administration of 2 mg to young and elderly patients with mild-to-moderate hypertension.
    Arner P, Wade A, Engfeldt P, Mouren M, Stepniewski JP, Sultan E, Bryce T, Lenfant B.
    J Cardiovasc Pharmacol; 1994 Mar 01; 23 Suppl 4():S44-9. PubMed ID: 7527101
    [Abstract] [Full Text] [Related]

  • 18. Physiologically-Based Pharmacokinetic Modeling to Predict Methylphenidate Exposure Affected by Interplay Among Carboxylesterase 1 Pharmacogenetics, Drug-Drug Interactions, and Sex.
    Xiao J, Shi J, Thompson BR, Smith DE, Zhang T, Zhu HJ.
    J Pharm Sci; 2022 Sep 01; 111(9):2606-2613. PubMed ID: 35526575
    [Abstract] [Full Text] [Related]

  • 19. Effect of renal function on the pharmacokinetics and pharmacodynamics of trandolapril.
    Bevan EG, McInnes GT, Aldigier JC, Conte JJ, Grunfeld JP, Harper SJ, Meyer BH, Pauly N, Wilkinson R.
    Br J Clin Pharmacol; 1993 Feb 01; 35(2):128-35. PubMed ID: 8443030
    [Abstract] [Full Text] [Related]

  • 20. Effects of Genetic Variants on Carboxylesterase 1 Gene Expression, and Clopidogrel Pharmacokinetics and Antiplatelet Effects.
    Neuvonen M, Tarkiainen EK, Tornio A, Hirvensalo P, Tapaninen T, Paile-Hyvärinen M, Itkonen MK, Holmberg MT, Kärjä V, Männistö VT, Neuvonen PJ, Pihlajamäki J, Backman JT, Niemi M.
    Basic Clin Pharmacol Toxicol; 2018 Mar 01; 122(3):341-345. PubMed ID: 28990360
    [Abstract] [Full Text] [Related]

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