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Journal Abstract Search

398 related items for PubMed ID: 33668611

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  • 2. Alpha 1-Antitrypsin Deficiency: A Disorder of Proteostasis-Mediated Protein Folding and Trafficking Pathways.
    Karatas E, Bouchecareilh M.
    Int J Mol Sci; 2020 Feb 21; 21(4):. PubMed ID: 32098273
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  • 5. Multiple Genes Core to ERAD, Macroautophagy and Lysosomal Degradation Pathways Participate in the Proteostasis Response in α1-Antitrypsin Deficiency.
    Li J, Moretti F, Hidvegi T, Sviben S, Fitzpatrick JAJ, Sundaramoorthi H, Pak SC, Silverman GA, Knapp B, Filipuzzi I, Alford J, Reece-Hoyes J, Nigsch F, Murphy LO, Nyfeler B, Perlmutter DH.
    Cell Mol Gastroenterol Hepatol; 2024 Feb 21; 17(6):1007-1024. PubMed ID: 38336172
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  • 8. Sirtuin3 promotes the degradation of hepatic Z alpha-1 antitrypsin through lipophagy.
    Poole B, Oshins R, Huo Z, Aranyos A, West J, Duarte S, Clark VC, Beduschi T, Zarrinpar A, Brantly M, Khodayari N.
    Hepatol Commun; 2024 Feb 01; 8(2):. PubMed ID: 38285890
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  • 9. Modulation of calreticulin expression reveals a novel exosome-mediated mechanism of Z variant α1-antitrypsin disposal.
    Khodayari N, Oshins R, Alli AA, Tuna KM, Holliday LS, Krotova K, Brantly M.
    J Biol Chem; 2019 Apr 19; 294(16):6240-6252. PubMed ID: 30833329
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  • 10. Liver disease in alpha-1 antitrypsin deficiency: current understanding and future therapy.
    Teckman JH.
    COPD; 2013 Mar 19; 10 Suppl 1():35-43. PubMed ID: 23527737
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  • 11. Protein Misfolding and Aggregation: The Relatedness between Parkinson's Disease and Hepatic Endoplasmic Reticulum Storage Disorders.
    Padilla-Godínez FJ, Ramos-Acevedo R, Martínez-Becerril HA, Bernal-Conde LD, Garrido-Figueroa JF, Hiriart M, Hernández-López A, Argüero-Sánchez R, Callea F, Guerra-Crespo M.
    Int J Mol Sci; 2021 Nov 18; 22(22):. PubMed ID: 34830348
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  • 12. Heteropolymerization of α-1-antitrypsin mutants in cell models mimicking heterozygosity.
    Laffranchi M, Berardelli R, Ronzoni R, Lomas DA, Fra A.
    Hum Mol Genet; 2018 May 15; 27(10):1785-1793. PubMed ID: 29538751
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  • 13. Quantitative measurement of the histological features of alpha-1 antitrypsin deficiency-associated liver disease in biopsy specimens.
    Marek G, Collinsworth A, Liu C, Brantly M, Clark V.
    PLoS One; 2021 May 15; 16(8):e0256117. PubMed ID: 34398915
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  • 14. Alpha-1-antitrypsin deficiency: importance of proteasomal and autophagic degradative pathways in disposal of liver disease-associated protein aggregates.
    Perlmutter DH.
    Annu Rev Med; 2011 May 15; 62():333-45. PubMed ID: 20707674
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  • 15. Clinical and histologic features of adults with alpha-1 antitrypsin deficiency in a non-cirrhotic cohort.
    Clark VC, Marek G, Liu C, Collinsworth A, Shuster J, Kurtz T, Nolte J, Brantly M.
    J Hepatol; 2018 Dec 15; 69(6):1357-1364. PubMed ID: 30138687
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  • 16. Bone marrow stem cell therapy partially ameliorates pathological consequences in livers of mice expressing mutant human α1-antitrypsin.
    Baligar P, Kochat V, Arindkar SK, Equbal Z, Mukherjee S, Patel S, Nagarajan P, Mohanty S, Teckman JH, Mukhopadhyay A.
    Hepatology; 2017 Apr 15; 65(4):1319-1335. PubMed ID: 28056498
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  • 17. NFκB mitigates the pathological effects of misfolded α1-antitrypsin by activating autophagy and an integrated program of proteostasis mechanisms.
    Mukherjee A, Hidvegi T, Araya P, Ewing M, Stolz DB, Perlmutter DH.
    Cell Death Differ; 2019 Mar 15; 26(3):455-469. PubMed ID: 29795336
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  • 18. Alpha-1 Antitrypsin Deficiency and Accelerated Aging: A New Model for an Old Disease?
    Crossley D, Stockley R, Sapey E.
    Drugs Aging; 2019 Sep 15; 36(9):823-840. PubMed ID: 31179525
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  • 19. The pathological Trento variant of alpha-1-antitrypsin (E75V) shows nonclassical behaviour during polymerization.
    Miranda E, Ferrarotti I, Berardelli R, Laffranchi M, Cerea M, Gangemi F, Haq I, Ottaviani S, Lomas DA, Irving JA, Fra A.
    FEBS J; 2017 Jul 15; 284(13):2110-2126. PubMed ID: 28504839
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  • 20. Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of α-1 Antitrypsin Deficiency.
    Borel F, Tang Q, Gernoux G, Greer C, Wang Z, Barzel A, Kay MA, Shultz LD, Greiner DL, Flotte TR, Brehm MA, Mueller C.
    Mol Ther; 2017 Nov 01; 25(11):2477-2489. PubMed ID: 29032169
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