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Journal Abstract Search


317 related items for PubMed ID: 33689753

  • 1. The cytotoxic effect of Clostridioides difficile pore-forming toxin CDTb.
    Landenberger M, Nieland J, Roeder M, Nørgaard K, Papatheodorou P, Ernst K, Barth H.
    Biochim Biophys Acta Biomembr; 2021 Jun 01; 1863(6):183603. PubMed ID: 33689753
    [Abstract] [Full Text] [Related]

  • 2. Characterization and Pharmacological Inhibition of the Pore-Forming Clostridioides difficile CDTb Toxin.
    Ernst K, Landenberger M, Nieland J, Nørgaard K, Frick M, Fois G, Benz R, Barth H.
    Toxins (Basel); 2021 May 28; 13(6):. PubMed ID: 34071730
    [Abstract] [Full Text] [Related]

  • 3. Membrane translocation of binary actin-ADP-ribosylating toxins from Clostridium difficile and Clostridium perfringens is facilitated by cyclophilin A and Hsp90.
    Kaiser E, Kroll C, Ernst K, Schwan C, Popoff M, Fischer G, Buchner J, Aktories K, Barth H.
    Infect Immun; 2011 Oct 28; 79(10):3913-21. PubMed ID: 21768281
    [Abstract] [Full Text] [Related]

  • 4. Clostridium difficile binary toxin CDT induces clustering of the lipolysis-stimulated lipoprotein receptor into lipid rafts.
    Papatheodorou P, Hornuss D, Nölke T, Hemmasi S, Castonguay J, Picchianti M, Aktories K.
    mBio; 2013 Apr 30; 4(3):e00244-13. PubMed ID: 23631918
    [Abstract] [Full Text] [Related]

  • 5. Tailored cyclodextrin pore blocker protects mammalian cells from clostridium difficile binary toxin CDT.
    Roeder M, Nestorovich EM, Karginov VA, Schwan C, Aktories K, Barth H.
    Toxins (Basel); 2014 Jul 15; 6(7):2097-114. PubMed ID: 25029374
    [Abstract] [Full Text] [Related]

  • 6. Human intestinal enteroids as a model of Clostridioides difficile-induced enteritis.
    Engevik MA, Danhof HA, Chang-Graham AL, Spinler JK, Engevik KA, Herrmann B, Endres BT, Garey KW, Hyser JM, Britton RA, Versalovic J.
    Am J Physiol Gastrointest Liver Physiol; 2020 May 01; 318(5):G870-G888. PubMed ID: 32223302
    [Abstract] [Full Text] [Related]

  • 7. Study of the frequency of Clostridium difficile tcdA, tcdB, cdtA and cdtB genes in feces of Calves in south west of Iran.
    Doosti A, Mokhtari-Farsani A.
    Ann Clin Microbiol Antimicrob; 2014 Jun 05; 13():21. PubMed ID: 24903619
    [Abstract] [Full Text] [Related]

  • 8. Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a di-heptamer macromolecular assembly.
    Xu X, Godoy-Ruiz R, Adipietro KA, Peralta C, Ben-Hail D, Varney KM, Cook ME, Roth BM, Wilder PT, Cleveland T, Grishaev A, Neu HM, Michel SLJ, Yu W, Beckett D, Rustandi RR, Lancaster C, Loughney JW, Kristopeit A, Christanti S, Olson JW, MacKerell AD, Georges AD, Pozharski E, Weber DJ.
    Proc Natl Acad Sci U S A; 2020 Jan 14; 117(2):1049-1058. PubMed ID: 31896582
    [Abstract] [Full Text] [Related]

  • 9. Clostridium difficile binary toxin CDT: mechanism, epidemiology, and potential clinical importance.
    Gerding DN, Johnson S, Rupnik M, Aktories K.
    Gut Microbes; 2014 Jan 14; 5(1):15-27. PubMed ID: 24253566
    [Abstract] [Full Text] [Related]

  • 10. Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin.
    Goldsmith JA, Dewar V, Hermand P, Blais N, McLellan JS.
    J Bacteriol; 2023 Apr 25; 205(4):e0045622. PubMed ID: 36951574
    [Abstract] [Full Text] [Related]

  • 11. The Importance of Therapeutically Targeting the Binary Toxin from Clostridioides difficile.
    Abeyawardhane DL, Godoy-Ruiz R, Adipietro KA, Varney KM, Rustandi RR, Pozharski E, Weber DJ.
    Int J Mol Sci; 2021 Mar 13; 22(6):. PubMed ID: 33805767
    [Abstract] [Full Text] [Related]

  • 12. 1HN, 13C, and 15N resonance assignments of the Clostridioides difficile receptor binding domain 2 (CDTb, residues 757-876).
    Cook ME, Varney KM, Godoy-Ruiz R, Weber DJ.
    Biomol NMR Assign; 2021 Apr 13; 15(1):35-39. PubMed ID: 33034833
    [Abstract] [Full Text] [Related]

  • 13. Interaction of the Clostridium difficile Binary Toxin CDT and Its Host Cell Receptor, Lipolysis-stimulated Lipoprotein Receptor (LSR).
    Hemmasi S, Czulkies BA, Schorch B, Veit A, Aktories K, Papatheodorou P.
    J Biol Chem; 2015 May 29; 290(22):14031-44. PubMed ID: 25882847
    [Abstract] [Full Text] [Related]

  • 14. (1)H(N), (13)C, and (15)N resonance assignments of the CDTb-interacting domain (CDTaBID) from the Clostridium difficile binary toxin catalytic component (CDTa, residues 1-221).
    Roth BM, Varney KM, Rustandi RR, Weber DJ.
    Biomol NMR Assign; 2016 Oct 29; 10(2):335-9. PubMed ID: 27351891
    [Abstract] [Full Text] [Related]

  • 15. Structural elucidation of the Clostridioides difficile transferase toxin reveals a single-site binding mode for the enzyme.
    Sheedlo MJ, Anderson DM, Thomas AK, Lacy DB.
    Proc Natl Acad Sci U S A; 2020 Mar 17; 117(11):6139-6144. PubMed ID: 32123082
    [Abstract] [Full Text] [Related]

  • 16. Human peptide α-defensin-1 interferes with Clostridioides difficile toxins TcdA, TcdB, and CDT.
    Fischer S, Ückert AK, Landenberger M, Papatheodorou P, Hoffmann-Richter C, Mittler AK, Ziener U, Hägele M, Schwan C, Müller M, Kleger A, Benz R, Popoff MR, Aktories K, Barth H.
    FASEB J; 2020 May 17; 34(5):6244-6261. PubMed ID: 32190927
    [Abstract] [Full Text] [Related]

  • 17. Human α-Defensin-5 Efficiently Neutralizes Clostridioides difficile Toxins TcdA, TcdB, and CDT.
    Korbmacher M, Fischer S, Landenberger M, Papatheodorou P, Aktories K, Barth H.
    Front Pharmacol; 2020 May 17; 11():1204. PubMed ID: 32903430
    [Abstract] [Full Text] [Related]

  • 18. Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile.
    Kawamoto A, Yamada T, Yoshida T, Sato Y, Kato T, Tsuge H.
    Nat Commun; 2022 Oct 17; 13(1):6119. PubMed ID: 36253419
    [Abstract] [Full Text] [Related]

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