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Journal Abstract Search


109 related items for PubMed ID: 33721990

  • 1. Atomic-Resolution 1.3 Å Crystal Structure, Inhibition by Sulfate, and Molecular Dynamics of the Bacterial Enzyme DapE.
    Kochert M, Nocek BP, Habeeb Mohammad TS, Gild E, Lovato K, Heath TK, Holz RC, Olsen KW, Becker DP.
    Biochemistry; 2021 Mar 30; 60(12):908-917. PubMed ID: 33721990
    [Abstract] [Full Text] [Related]

  • 2. Structural Evidence of a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism.
    Nocek B, Reidl C, Starus A, Heath T, Bienvenue D, Osipiuk J, Jedrzejczak R, Joachimiak A, Becker DP, Holz RC.
    Biochemistry; 2018 Feb 06; 57(5):574-584. PubMed ID: 29272107
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril.
    Starus A, Nocek B, Bennett B, Larrabee JA, Shaw DL, Sae-Lee W, Russo MT, Gillner DM, Makowska-Grzyska M, Joachimiak A, Holz RC.
    Biochemistry; 2015 Aug 11; 54(31):4834-44. PubMed ID: 26186504
    [Abstract] [Full Text] [Related]

  • 4. Substrate specificity, metal binding properties, and spectroscopic characterization of the DapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase from Haemophilus influenzae.
    Bienvenue DL, Gilner DM, Davis RS, Bennett B, Holz RC.
    Biochemistry; 2003 Sep 16; 42(36):10756-63. PubMed ID: 12962500
    [Abstract] [Full Text] [Related]

  • 5. Structural basis for catalysis by the mono- and dimetalated forms of the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase.
    Nocek BP, Gillner DM, Fan Y, Holz RC, Joachimiak A.
    J Mol Biol; 2010 Apr 02; 397(3):617-26. PubMed ID: 20138056
    [Abstract] [Full Text] [Related]

  • 6. The dimerization domain in DapE enzymes is required for catalysis.
    Nocek B, Starus A, Makowska-Grzyska M, Gutierrez B, Sanchez S, Jedrzejczak R, Mack JC, Olsen KW, Joachimiak A, Holz RC.
    PLoS One; 2014 Apr 02; 9(5):e93593. PubMed ID: 24806882
    [Abstract] [Full Text] [Related]

  • 7. The dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase from Haemophilus influenzae contains two active-site histidine residues.
    Gillner DM, Bienvenue DL, Nocek BP, Joachimiak A, Zachary V, Bennett B, Holz RC.
    J Biol Inorg Chem; 2009 Jan 02; 14(1):1-10. PubMed ID: 18712420
    [Abstract] [Full Text] [Related]

  • 8. The structural and energetic aspects of substrate binding and the mechanism of action of the DapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) investigated using a hybrid QM/MM method.
    Dutta D, Mishra S.
    Phys Chem Chem Phys; 2014 Dec 21; 16(47):26348-58. PubMed ID: 25367594
    [Abstract] [Full Text] [Related]

  • 9. Practical spectrophotometric assay for the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase, a potential antibiotic target.
    Heath TK, Lutz MR, Reidl CT, Guzman ER, Herbert CA, Nocek BP, Holz RC, Olsen KW, Ballicora MA, Becker DP.
    PLoS One; 2018 Dec 21; 13(4):e0196010. PubMed ID: 29698518
    [Abstract] [Full Text] [Related]

  • 10. The dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase from Haemophilus influenzae is a dinuclear metallohydrolase.
    Cosper NJ, Bienvenue DL, Shokes JE, Gilner DM, Tsukamoto T, Scott RA, Holz RC.
    J Am Chem Soc; 2003 Dec 03; 125(48):14654-5. PubMed ID: 14640610
    [Abstract] [Full Text] [Related]

  • 11. In silico approach towards identification of potential inhibitors of Helicobacter pylori DapE.
    Mandal RS, Das S.
    J Biomol Struct Dyn; 2015 Dec 03; 33(7):1460-73. PubMed ID: 25204745
    [Abstract] [Full Text] [Related]

  • 12. Zinc-selective inhibition of the promiscuous bacterial amide-hydrolase DapE: implications of metal heterogeneity for evolution and antibiotic drug design.
    Uda NR, Upert G, Angelici G, Nicolet S, Schmidt T, Schwede T, Creus M.
    Metallomics; 2014 Jan 03; 6(1):88-95. PubMed ID: 24057071
    [Abstract] [Full Text] [Related]

  • 13. Lysine biosynthesis in bacteria: a metallodesuccinylase as a potential antimicrobial target.
    Gillner DM, Becker DP, Holz RC.
    J Biol Inorg Chem; 2013 Feb 03; 18(2):155-163. PubMed ID: 23223968
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and characterization of the N-succinyl-l,l-diaminopimelic acid desuccinylase (DapE) alternate substrate analog N,N-dimethyl-l,l-SDAP.
    Liveris ZJ, Kelley EH, Simmons E, Konczak K, Lutz MR, Ballicora M, Olsen KW, Becker DP.
    Bioorg Med Chem; 2023 Aug 15; 91():117415. PubMed ID: 37459673
    [Abstract] [Full Text] [Related]

  • 15. Kinetic and spectroscopic characterization of the E134A- and E134D-altered dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase from Haemophilus influenzae.
    Davis R, Bienvenue D, Swierczek SI, Gilner DM, Rajagopal L, Bennett B, Holz RC.
    J Biol Inorg Chem; 2006 Mar 15; 11(2):206-16. PubMed ID: 16421726
    [Abstract] [Full Text] [Related]

  • 16. Loss of Catalytic Activity in the E134D, H67A, and H349A Mutants of DapE: Mechanistic Analysis with QM/MM Investigation.
    Dutta D, Mishra S.
    J Phys Chem B; 2016 Nov 17; 120(45):11654-11664. PubMed ID: 27783518
    [Abstract] [Full Text] [Related]

  • 17. The three-dimensional structure of DapE from Enterococcus faecium reveals new insights into DapE/ArgE subfamily ligand specificity.
    Terrazas-López M, González-Segura L, Díaz-Vilchis A, Aguirre-Mendez KA, Lobo-Galo N, Martínez-Martínez A, Díaz-Sánchez ÁG.
    Int J Biol Macromol; 2024 Jun 17; 270(Pt 2):132281. PubMed ID: 38740150
    [Abstract] [Full Text] [Related]

  • 18. Reconstruction of diaminopimelic acid biosynthesis allows characterisation of Mycobacterium tuberculosis N-succinyl-L,L-diaminopimelic acid desuccinylase.
    Usha V, Lloyd AJ, Roper DI, Dowson CG, Kozlov G, Gehring K, Chauhan S, Imam HT, Blindauer CA, Besra GS.
    Sci Rep; 2016 Mar 15; 6():23191. PubMed ID: 26976706
    [Abstract] [Full Text] [Related]

  • 19. Biochemical and Structural Analysis of the Bacterial Enzyme Succinyl-Diaminopimelate Desuccinylase (DapE) from Acinetobacter baumannii.
    Kelley EH, Minasov G, Konczak K, Shuvalova L, Brunzelle JS, Shukla S, Beulke M, Thabthimthong T, Olsen KW, Inniss NL, Satchell KJF, Becker DP.
    ACS Omega; 2024 Jan 23; 9(3):3905-3915. PubMed ID: 38284080
    [Abstract] [Full Text] [Related]

  • 20. Inhibitors of bacterial N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) and demonstration of in vitro antimicrobial activity.
    Gillner D, Armoush N, Holz RC, Becker DP.
    Bioorg Med Chem Lett; 2009 Nov 15; 19(22):6350-2. PubMed ID: 19822427
    [Abstract] [Full Text] [Related]


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