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Journal Abstract Search

297 related items for PubMed ID: 33730937

  • 1. Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect.
    Ibrahim TS, Hawwas MM, Malebari AM, Taher ES, Omar AM, Neamatallah T, Abdel-Samii ZK, Safo MK, Elshaier YAMM.
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):802-818. PubMed ID: 33730937
    [Abstract] [Full Text] [Related]

  • 2. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
    Hagras M, El Deeb MA, Elzahabi HSA, Elkaeed EB, Mehany ABM, Eissa IH.
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):640-658. PubMed ID: 33588683
    [Abstract] [Full Text] [Related]

  • 3. A 2-step synthesis of Combretastatin A-4 and derivatives as potent tubulin assembly inhibitors.
    Barnes NG, Parker AW, Ahmed Mal Ullah AA, Ragazzon PA, Hadfield JA.
    Bioorg Med Chem; 2020 Oct 01; 28(19):115684. PubMed ID: 32912434
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T, Mikstacka R, Kurczab R, Dutkiewicz Z, Kucińska M, Murias M, Zielińska-Przyjemska M, Cichocki M, Teubert A, Kaczmarek M, Hogendorf A, Sobiak S.
    Eur J Med Chem; 2018 Jan 20; 144():797-816. PubMed ID: 29291446
    [Abstract] [Full Text] [Related]

  • 5. Synthesis of Combretastatin-A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization.
    Jadala C, Sathish M, Anchi P, Tokala R, Lakshmi UJ, Reddy VG, Shankaraiah N, Godugu C, Kamal A.
    ChemMedChem; 2019 Dec 17; 14(24):2052-2060. PubMed ID: 31674147
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis and biological evaluation of novel thiazole-naphthalene derivatives as potential anticancer agents and tubulin polymerisation inhibitors.
    Wang G, Liu W, Fan M, He M, Li Y, Peng Z.
    J Enzyme Inhib Med Chem; 2021 Dec 17; 36(1):1694-1702. PubMed ID: 34309466
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and biological evaluation of quinoline analogues of flavones as potential anticancer agents and tubulin polymerization inhibitors.
    Shobeiri N, Rashedi M, Mosaffa F, Zarghi A, Ghandadi M, Ghasemi A, Ghodsi R.
    Eur J Med Chem; 2016 May 23; 114():14-23. PubMed ID: 26974371
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and biological evaluation of novel acridine and quinoline derivatives as tubulin polymerization inhibitors with anticancer activities.
    Ren Y, Ruan Y, Cheng B, Li L, Liu J, Fang Y, Chen J.
    Bioorg Med Chem; 2021 Sep 15; 46():116376. PubMed ID: 34455231
    [Abstract] [Full Text] [Related]

  • 9. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 15; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 10. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and biological evaluation of 4-phenyl-5-quinolinyl substituted isoxazole analogues as potent cytotoxic and tubulin polymerization inhibitors against ESCC.
    Jia M, Pei Y, Li N, Zhang Y, Song J, Niu JB, Yang H, Zhang S, Sun M.
    Eur J Med Chem; 2024 Sep 05; 275():116611. PubMed ID: 38901104
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and bio-evaluation of novel quinolino-stilbene derivatives as potential anticancer agents.
    Srivastava V, Lee H.
    Bioorg Med Chem; 2015 Dec 15; 23(24):7629-40. PubMed ID: 26602827
    [Abstract] [Full Text] [Related]

  • 13. Potent combretastatin A-4 analogs containing 1,2,4-triazole: Synthesis, antiproliferative, anti-tubulin activity, and docking study.
    Mustafa M, Anwar S, Elgamal F, Ahmed ER, Aly OM.
    Eur J Med Chem; 2019 Dec 01; 183():111697. PubMed ID: 31536891
    [Abstract] [Full Text] [Related]

  • 14. Design, concise synthesis and evaluation of novel amide-based combretastatin A-4 analogues as potent tubulin inhibitors.
    Ma Y, Wang T, Cheng L, Ma X, Li R, Zhang M, Chen J, Zhao P.
    Bioorg Med Chem Lett; 2024 Aug 01; 108():129816. PubMed ID: 38806101
    [Abstract] [Full Text] [Related]

  • 15. Discovery of novel tubulin/HDAC dual-targeting inhibitors with strong antitumor and antiangiogenic potency.
    Wang Y, Sun M, Wang Y, Qin J, Zhang Y, Pang Y, Yao Y, Yang H, Duan Y.
    Eur J Med Chem; 2021 Dec 05; 225():113790. PubMed ID: 34454126
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis of combretastatin A-4 piperazine derivatives as potential antitumor agents by inhibiting tubulin polymerization and inducing autophagy in HCT116 cells.
    Zhang H, Li M, Zhou X, Tang L, Chen G, Zhang Y.
    Eur J Med Chem; 2024 Jun 05; 272():116497. PubMed ID: 38759453
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and biological evaluation of novel imidazole-chalcone derivatives as potential anticancer agents and tubulin polymerization inhibitors.
    Rahimzadeh Oskuei S, Mirzaei S, Reza Jafari-Nik M, Hadizadeh F, Eisvand F, Mosaffa F, Ghodsi R.
    Bioorg Chem; 2021 Jul 05; 112():104904. PubMed ID: 33933802
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and bioevaluation of 2,7-diaryl-pyrazolo[1,5-a]pyrimidines as tubulin polymerization inhibitors.
    Liu R, Zhang S, Huang M, Guo Z, Li L, Li M, Wu L, Guan Q, Zhang W.
    Bioorg Chem; 2021 Oct 05; 115():105220. PubMed ID: 34352709
    [Abstract] [Full Text] [Related]

  • 19. Design, Synthesis and Antitumor Activity of Novel link-bridge and B-Ring Modified Combretastatin A-4 (CA-4) Analogues as Potent Antitubulin Agents.
    Duan YT, Man RJ, Tang DJ, Yao YF, Tao XX, Yu C, Liang XY, Makawana JA, Zou MJ, Wang ZC, Zhu HL.
    Sci Rep; 2016 May 03; 6():25387. PubMed ID: 27138035
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
    Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y.
    Eur J Med Chem; 2018 Jan 20; 144():817-842. PubMed ID: 29306206
    [Abstract] [Full Text] [Related]

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