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637 related items for PubMed ID: 33735711

  • 1. Development of adamantane scaffold containing 1,3,4-thiadiazole derivatives: Design, synthesis, anti-proliferative activity and molecular docking study targeting EGFR.
    Wassel MMS, Ammar YA, Elhag Ali GAM, Belal A, Mehany ABM, Ragab A.
    Bioorg Chem; 2021 May; 110():104794. PubMed ID: 33735711
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis and anticancer evaluation of 1H-pyrazolo[3,4-d]pyrimidine derivatives as potent EGFRWT and EGFRT790M inhibitors and apoptosis inducers.
    Gaber AA, Bayoumi AH, El-Morsy AM, Sherbiny FF, Mehany ABM, Eissa IH.
    Bioorg Chem; 2018 Oct; 80():375-395. PubMed ID: 29986185
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis and biological evaluation of new series of hexahydroquinoline and fused quinoline derivatives as potent inhibitors of wild-type EGFR and mutant EGFR (L858R and T790M).
    Shaheen MA, El-Emam AA, El-Gohary NS.
    Bioorg Chem; 2020 Dec; 105():104274. PubMed ID: 33339080
    [Abstract] [Full Text] [Related]

  • 4. Design, microwave assisted synthesis, and molecular modeling study of some new 1,3,4-thiadiazole derivatives as potent anticancer agents and potential VEGFR-2 inhibitors.
    Atta-Allah SR, AboulMagd AM, Farag PS.
    Bioorg Chem; 2021 Jul; 112():104923. PubMed ID: 33932767
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as dual EGFR/HER2 inhibitors and apoptosis inducers.
    Elmetwally SA, Saied KF, Eissa IH, Elkaeed EB.
    Bioorg Chem; 2019 Jul; 88():102944. PubMed ID: 31051400
    [Abstract] [Full Text] [Related]

  • 6. Design, Synthesis, biological Evaluation, and molecular docking studies of novel Pyrazolo[3,4-d]Pyrimidine derivative scaffolds as potent EGFR inhibitors and cell apoptosis inducers.
    Sherbiny FF, Bayoumi AH, El-Morsy AM, Sobhy M, Hagras M.
    Bioorg Chem; 2021 Nov; 116():105325. PubMed ID: 34507234
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis and biological evaluation of novel N-(3-amino-4-methoxyphenyl)acrylamide derivatives as selective EGFRL858R/T790M kinase inhibitors.
    Ding S, Dong X, Gao Z, Zheng X, Ji J, Zhang M, Liu F, Wu S, Li M, Song W, Shen J, Duan W, Liu J, Chen Y.
    Bioorg Chem; 2022 Jan; 118():105471. PubMed ID: 34798457
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and biological evaluation of novel 4-anlinoquinazoline derivatives as EGFR inhibitors with the potential to inhibit the gefitinib-resistant nonsmall cell lung cancers.
    Wang C, Xu S, Peng L, Zhang B, Zhang H, Hu Y, Zheng P, Zhu W.
    J Enzyme Inhib Med Chem; 2019 Dec; 34(1):203-217. PubMed ID: 30835140
    [Abstract] [Full Text] [Related]

  • 9. Discovery of new pyrimidine-5-carbonitrile derivatives as anticancer agents targeting EGFRWT and EGFRT790M.
    Nasser AA, Eissa IH, Oun MR, El-Zahabi MA, Taghour MS, Belal A, Saleh AM, Mehany ABM, Luesch H, Mostafa AE, Afifi WM, Rocca JR, Mahdy HA.
    Org Biomol Chem; 2020 Oct 07; 18(38):7608-7634. PubMed ID: 32959865
    [Abstract] [Full Text] [Related]

  • 10. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
    Hagras M, El Deeb MA, Elzahabi HSA, Elkaeed EB, Mehany ABM, Eissa IH.
    J Enzyme Inhib Med Chem; 2021 Dec 07; 36(1):640-658. PubMed ID: 33588683
    [Abstract] [Full Text] [Related]

  • 11. Novel benzothiazole-based dual VEGFR-2/EGFR inhibitors targeting breast and liver cancers: Synthesis, cytotoxic activity, QSAR and molecular docking studies.
    Abd El-Meguid EA, Naglah AM, Moustafa GO, Awad HM, El Kerdawy AM.
    Bioorg Med Chem Lett; 2022 Feb 15; 58():128529. PubMed ID: 35007724
    [Abstract] [Full Text] [Related]

  • 12. Discovery of new thieno[3,2-d]pyrimidine derivatives targeting EGFRL858R/T790M NSCLCs by the conformation constrained strategy.
    Chen Y, Yang L, Qiao H, Cheng Z, Xie J, Zhou W, Huang X, Jiang Y, Yu B, Zhao W.
    Eur J Med Chem; 2020 Aug 01; 199():112388. PubMed ID: 32402937
    [Abstract] [Full Text] [Related]

  • 13. Design and synthesis of novel Thiazolo[5,4-b]pyridine derivatives as potent and selective EGFR-TK inhibitors targeting resistance Mutations in non-small cell lung cancer.
    Borude AS, Deshmukh SR, Tiwari SV, Kumar SH, Thopate SR.
    Eur J Med Chem; 2024 Oct 05; 276():116727. PubMed ID: 39094428
    [Abstract] [Full Text] [Related]

  • 14. Synthesis, biological evaluation, and molecular docking studies of cinnamic acyl 1,3,4-thiadiazole amide derivatives as novel antitubulin agents.
    Yang XH, Wen Q, Zhao TT, Sun J, Li X, Xing M, Lu X, Zhu HL.
    Bioorg Med Chem; 2012 Feb 01; 20(3):1181-7. PubMed ID: 22261027
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and evaluation of anti-proliferative activity of 2-aryl-4-aminoquinazoline derivatives as EGFR inhibitors.
    Zhou Z, He J, Yang F, Pan Q, Yang Z, Zheng P, Xu S, Zhu W.
    Bioorg Chem; 2021 Jul 01; 112():104848. PubMed ID: 33819737
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis and biological evaluation of potent EGFR kinase inhibitors against 19D/T790M/C797S mutation.
    Su Z, Yang T, Wang J, Lai M, Tong L, Wumaier G, Chen Z, Li S, Li H, Xie H, Zhao Z.
    Bioorg Med Chem Lett; 2020 Aug 15; 30(16):127327. PubMed ID: 32631532
    [Abstract] [Full Text] [Related]

  • 17. Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.
    Alswah M, Bayoumi AH, Elgamal K, Elmorsy A, Ihmaid S, Ahmed HEA.
    Molecules; 2017 Dec 27; 23(1):. PubMed ID: 29280968
    [Abstract] [Full Text] [Related]

  • 18. Discovery of novel pyrazole based Urea/Thiourea derivatives as multiple targeting VEGFR-2, EGFRWT, EGFRT790M tyrosine kinases and COX-2 Inhibitors, with anti-cancer and anti-inflammatory activities.
    Fadaly WAA, Nemr MTM, Kahk NM.
    Bioorg Chem; 2024 Jun 27; 147():107403. PubMed ID: 38691909
    [Abstract] [Full Text] [Related]

  • 19. Targeting EGFR tyrosine kinase: Synthesis, in vitro antitumor evaluation, and molecular modeling studies of benzothiazole-based derivatives.
    Mokhtar AM, El-Messery SM, Ghaly MA, Hassan GS.
    Bioorg Chem; 2020 Nov 27; 104():104259. PubMed ID: 32919134
    [Abstract] [Full Text] [Related]

  • 20. New antiproliferative 3-substituted oxindoles inhibiting EGFR/VEGFR-2 and tubulin polymerization.
    Ezelarab HAA, Ali TFS, Abbas SH, Sayed AM, Beshr EAM, Hassan HA.
    Mol Divers; 2024 Apr 27; 28(2):563-580. PubMed ID: 36790582
    [Abstract] [Full Text] [Related]

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