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157 related items for PubMed ID: 33753770

  • 1. LLL12B, a small molecule STAT3 inhibitor, induces growth arrest, apoptosis, and enhances cisplatin-mediated cytotoxicity in medulloblastoma cells.
    Chen X, Pan L, Wei J, Zhang R, Yang X, Song J, Bai RY, Fu S, Pierson CR, Finlay JL, Li C, Lin J.
    Sci Rep; 2021 Mar 22; 11(1):6517. PubMed ID: 33753770
    [Abstract] [Full Text] [Related]

  • 2. A novel small molecule LLL12B inhibits STAT3 signaling and sensitizes ovarian cancer cell to paclitaxel and cisplatin.
    Zhang R, Yang X, Roque DM, Li C, Lin J.
    PLoS One; 2021 Mar 22; 16(4):e0240145. PubMed ID: 33909625
    [Abstract] [Full Text] [Related]

  • 3. STAT3 inhibitor in combination with irradiation significantly inhibits cell viability, cell migration, invasion and tumorsphere growth of human medulloblastoma cells.
    Pan L, Zhang R, Ma L, Pierson CR, Finlay JL, Li C, Lin J.
    Cancer Biol Ther; 2021 Sep 02; 22(7-9):430-439. PubMed ID: 34254873
    [Abstract] [Full Text] [Related]

  • 4. A novel small molecular STAT3 inhibitor, LY5, inhibits cell viability, cell migration, and angiogenesis in medulloblastoma cells.
    Xiao H, Bid HK, Jou D, Wu X, Yu W, Li C, Houghton PJ, Lin J.
    J Biol Chem; 2015 Feb 06; 290(6):3418-29. PubMed ID: 25313399
    [Abstract] [Full Text] [Related]

  • 5. The small molecule, LLL12, inhibits STAT3 phosphorylation and induces apoptosis in medulloblastoma and glioblastoma cells.
    Ball S, Li C, Li PK, Lin J.
    PLoS One; 2011 Apr 19; 6(4):e18820. PubMed ID: 21526200
    [Abstract] [Full Text] [Related]

  • 6. A small molecule STAT3 inhibitor, LLL12, enhances cisplatin‑ and paclitaxel‑mediated inhibition of cell growth and migration in human ovarian cancer cells.
    Zhang R, Chen X, Fu S, Xu L, Lin J.
    Oncol Rep; 2020 Sep 19; 44(3):1224-1232. PubMed ID: 32705214
    [Abstract] [Full Text] [Related]

  • 7. Targeting Upstream Kinases of STAT3 in Human Medulloblastoma Cells.
    Wei J, Ma L, Li C, Pierson CR, Finlay JL, Lin J.
    Curr Cancer Drug Targets; 2019 Sep 19; 19(7):571-582. PubMed ID: 30332965
    [Abstract] [Full Text] [Related]

  • 8. LLL12B, a Novel Small-Molecule STAT3 Inhibitor, Induces Apoptosis and Suppresses Cell Migration and Tumor Growth in Triple-Negative Breast Cancer Cells.
    Pan L, Chen X, Rassool FV, Li C, Lin J.
    Biomedicines; 2022 Aug 18; 10(8):. PubMed ID: 36009550
    [Abstract] [Full Text] [Related]

  • 9. A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells.
    Lin L, Benson DM, DeAngelis S, Bakan CE, Li PK, Li C, Lin J.
    Int J Cancer; 2012 Mar 15; 130(6):1459-69. PubMed ID: 21520044
    [Abstract] [Full Text] [Related]

  • 10. Suppression of STAT3 NH2 -terminal domain chemosensitizes medulloblastoma cells by activation of protein inhibitor of activated STAT3 via de-repression by microRNA-21.
    Ray S, Coulter DW, Gray SD, Sughroue JA, Roychoudhury S, McIntyre EM, Chaturvedi NK, Bhakat KK, Joshi SS, McGuire TR, Sharp JG.
    Mol Carcinog; 2018 Apr 15; 57(4):536-548. PubMed ID: 29280516
    [Abstract] [Full Text] [Related]

  • 11. Inhibitor of signal transducer and activator of transcription 3 (STAT3) suppresses ovarian cancer growth, migration and invasion and enhances the effect of cisplatin in vitro.
    Tang YJ, Sun ZL, Wu WG, Xing J, He YF, Xin DM, Han P.
    Genet Mol Res; 2015 Mar 30; 14(1):2450-60. PubMed ID: 25867391
    [Abstract] [Full Text] [Related]

  • 12. LLY17, a novel small molecule STAT3 inhibitor induces apoptosis and suppresses cell migration and tumor growth in triple-negative breast cancer.
    Pan L, Chen X, Fu S, Yu W, Li C, Wang T, Lo HW, Lin J.
    Breast Cancer Res Treat; 2020 May 30; 181(1):31-41. PubMed ID: 32240456
    [Abstract] [Full Text] [Related]

  • 13. LLL12, a novel small inhibitor targeting STAT3 for hepatocellular carcinoma therapy.
    Zuo M, Li C, Lin J, Javle M.
    Oncotarget; 2015 May 10; 6(13):10940-9. PubMed ID: 25883212
    [Abstract] [Full Text] [Related]

  • 14. PP2A inhibition with LB100 enhances cisplatin cytotoxicity and overcomes cisplatin resistance in medulloblastoma cells.
    Ho WS, Feldman MJ, Maric D, Amable L, Hall MD, Feldman GM, Ray-Chaudhury A, Lizak MJ, Vera JC, Robison RA, Zhuang Z, Heiss JD.
    Oncotarget; 2016 Mar 15; 7(11):12447-63. PubMed ID: 26799670
    [Abstract] [Full Text] [Related]

  • 15. Small molecules, LLL12 and FLLL32, inhibit STAT3 and exhibit potent growth suppressive activity in osteosarcoma cells and tumor growth in mice.
    Onimoe GI, Liu A, Lin L, Wei CC, Schwartz EB, Bhasin D, Li C, Fuchs JR, Li PK, Houghton P, Termuhlen A, Gross T, Lin J.
    Invest New Drugs; 2012 Jun 15; 30(3):916-26. PubMed ID: 21340507
    [Abstract] [Full Text] [Related]

  • 16. Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3).
    Kandala PK, Srivastava SK.
    BMC Med; 2012 Jan 26; 10():9. PubMed ID: 22280969
    [Abstract] [Full Text] [Related]

  • 17. Growth-suppressive activity of raloxifene on liver cancer cells by targeting IL-6/GP130 signaling.
    Wang Y, Ma H, Zhao C, Liu T, Yan D, Jou D, Li H, Zhang C, Lü J, Li C, Lin J, Li S, Lin L.
    Oncotarget; 2017 May 16; 8(20):33683-33693. PubMed ID: 28430601
    [Abstract] [Full Text] [Related]

  • 18. Curcumin-Mediated Apoptotic Cell Death in Papillary Thyroid Cancer and Cancer Stem-Like Cells through Targeting of the JAK/STAT3 Signaling Pathway.
    Khan AQ, Ahmed EI, Elareer N, Fathima H, Prabhu KS, Siveen KS, Kulinski M, Azizi F, Dermime S, Ahmad A, Steinhoff M, Uddin S.
    Int J Mol Sci; 2020 Jan 09; 21(2):. PubMed ID: 31936675
    [Abstract] [Full Text] [Related]

  • 19. Mild oxidative stress induces S-glutathionylation of STAT3 and enhances chemosensitivity of tumoural cells to chemotherapeutic drugs.
    Butturini E, Carcereri de Prati A, Chiavegato G, Rigo A, Cavalieri E, Darra E, Mariotto S.
    Free Radic Biol Med; 2013 Dec 09; 65():1322-1330. PubMed ID: 24095958
    [Abstract] [Full Text] [Related]

  • 20. A STAT3 inhibitor ameliorates CNS autoimmunity by restoring Teff:Treg balance.
    Aqel SI, Yang X, Kraus EE, Song J, Farinas MF, Zhao EY, Pei W, Lovett-Racke AE, Racke MK, Li C, Yang Y.
    JCI Insight; 2021 Feb 22; 6(4):. PubMed ID: 33411696
    [Abstract] [Full Text] [Related]

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