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Journal Abstract Search

274 related items for PubMed ID: 33768249

  • 1. Kcnq2/Kv7.2 controls the threshold and bi-hemispheric symmetry of cortical spreading depolarization.
    Aiba I, Noebels JL.
    Brain; 2021 Oct 22; 144(9):2863-2878. PubMed ID: 33768249
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  • 2. Effects of KCNQ2 gene truncation on M-type Kv7 potassium currents.
    Robbins J, Passmore GM, Abogadie FC, Reilly JM, Brown DA.
    PLoS One; 2013 Oct 22; 8(8):e71809. PubMed ID: 23977150
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  • 3. Retigabine, a Kv7.2/Kv7.3-Channel Opener, Attenuates Drug-Induced Seizures in Knock-In Mice Harboring Kcnq2 Mutations.
    Ihara Y, Tomonoh Y, Deshimaru M, Zhang B, Uchida T, Ishii A, Hirose S.
    PLoS One; 2016 Oct 22; 11(2):e0150095. PubMed ID: 26910900
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  • 4. Functional and behavioral signatures of Kv7 activator drug subtypes.
    Kanyo R, Wang CK, Locskai LF, Li J, Allison WT, Kurata HT.
    Epilepsia; 2020 Aug 22; 61(8):1678-1690. PubMed ID: 32652600
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  • 5. Kv7/M channel dysfunction produces hyperexcitability in hippocampal CA1 pyramidal cells of Fmr1 knockout mice.
    Luque MA, Morcuende S, Torres B, Herrero L.
    J Physiol; 2024 Aug 22; 602(15):3769-3791. PubMed ID: 38976504
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  • 6. Potent KCNQ2/3-specific channel activator suppresses in vivo epileptic activity and prevents the development of tinnitus.
    Kalappa BI, Soh H, Duignan KM, Furuya T, Edwards S, Tzingounis AV, Tzounopoulos T.
    J Neurosci; 2015 Jun 10; 35(23):8829-42. PubMed ID: 26063916
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  • 7. Removal of KCNQ2 from parvalbumin-expressing interneurons improves anti-seizure efficacy of retigabine.
    Jing J, Dunbar C, Sonesra A, Chavez A, Park S, Yang R, Soh H, Lee M, Tzingounis AV, Cooper EC, Jiang X, Maheshwari A.
    Exp Neurol; 2022 Sep 10; 355():114141. PubMed ID: 35691372
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  • 8. Persistent Na + current couples spreading depolarization to seizures in Scn8a gain of function mice.
    Aiba I, Ning Y, Noebels JL.
    bioRxiv; 2024 Oct 13. PubMed ID: 39416109
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  • 11. Attenuating M-current suppression in vivo by a mutant Kcnq2 gene knock-in reduces seizure burden and prevents status epilepticus-induced neuronal death and epileptogenesis.
    Greene DL, Kosenko A, Hoshi N.
    Epilepsia; 2018 Oct 13; 59(10):1908-1918. PubMed ID: 30146722
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  • 12. In vitro and in vivo characterization of Lu AA41178: A novel, brain penetrant, pan-selective Kv7 potassium channel opener with efficacy in preclinical models of epileptic seizures and psychiatric disorders.
    Grupe M, Bentzen BH, Benned-Jensen T, Nielsen V, Frederiksen K, Jensen HS, Jacobsen AM, Skibsbye L, Sams AG, Grunnet M, Rottländer M, Bastlund JF.
    Eur J Pharmacol; 2020 Nov 15; 887():173440. PubMed ID: 32745603
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  • 15. Functional analysis of potassium channels in Kv7.2 G271V mutant causing early onset familial epilepsy.
    Wang J, Li Y, Hui Z, Cao M, Shi R, Zhang W, Geng L, Zhou X.
    Brain Res; 2015 Aug 07; 1616():112-22. PubMed ID: 25960349
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  • 19. The Sensorless Pore Module of Voltage-gated K+ Channel Family 7 Embodies the Target Site for the Anticonvulsant Retigabine.
    Syeda R, Santos JS, Montal M.
    J Biol Chem; 2016 Feb 05; 291(6):2931-7. PubMed ID: 26627826
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  • 20. A knock-in mouse model for KCNQ2-related epileptic encephalopathy displays spontaneous generalized seizures and cognitive impairment.
    Milh M, Roubertoux P, Biba N, Chavany J, Spiga Ghata A, Fulachier C, Collins SC, Wagner C, Roux JC, Yalcin B, Félix MS, Molinari F, Lenck-Santini PP, Villard L.
    Epilepsia; 2020 May 05; 61(5):868-878. PubMed ID: 32239694
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