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Journal Abstract Search

442 related items for PubMed ID: 33770673

  • 1. Structure-activity relationships and antiproliferative effects of 1,2,3,4-4H-quinoxaline derivatives as tubulin polymerization inhibitors.
    Liang T, Zhou X, Lu L, Dong H, Zhang Y, Xu Y, Qi J, Zhang Y, Wang J.
    Bioorg Chem; 2021 May; 110():104793. PubMed ID: 33770673
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and biological evaluation of N-substituted 3-oxo-1,2,3,4-tetrahydro-quinoxaline-6-carboxylic acid derivatives as tubulin polymerization inhibitors.
    Qi J, Dong H, Huang J, Zhang S, Niu L, Zhang Y, Wang J.
    Eur J Med Chem; 2018 Jan 01; 143():8-20. PubMed ID: 29172084
    [Abstract] [Full Text] [Related]

  • 3. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 01; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 4. Design and synthesis of novel 5-(4-chlorophenyl)furan derivatives with inhibitory activity on tubulin polymerization.
    Moussa SA, A Osman EE, Eid NM, Abou-Seri SM, El Moghazy SM.
    Future Med Chem; 2018 Aug 01; 10(16):1907-1924. PubMed ID: 29966433
    [Abstract] [Full Text] [Related]

  • 5. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo.
    Cui YJ, Ma CC, Zhang CM, Tang LQ, Liu ZP.
    Eur J Med Chem; 2020 Feb 01; 187():111968. PubMed ID: 31865012
    [Abstract] [Full Text] [Related]

  • 6. Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors.
    Yang F, He CP, Diao PC, Hong KH, Rao JJ, Zhao PL.
    Bioorg Med Chem Lett; 2019 Jan 01; 29(1):22-27. PubMed ID: 30448234
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis and bioevaluation of 6-aryl-1-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazoles as tubulin polymerization inhibitors.
    Liu R, Huang M, Zhang S, Li L, Li M, Sun J, Wu L, Guan Q, Zhang W.
    Eur J Med Chem; 2021 Dec 15; 226():113826. PubMed ID: 34571171
    [Abstract] [Full Text] [Related]

  • 8. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
    Hagras M, El Deeb MA, Elzahabi HSA, Elkaeed EB, Mehany ABM, Eissa IH.
    J Enzyme Inhib Med Chem; 2021 Dec 15; 36(1):640-658. PubMed ID: 33588683
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis and bioevaluation of 2,7-diaryl-pyrazolo[1,5-a]pyrimidines as tubulin polymerization inhibitors.
    Liu R, Zhang S, Huang M, Guo Z, Li L, Li M, Wu L, Guan Q, Zhang W.
    Bioorg Chem; 2021 Oct 15; 115():105220. PubMed ID: 34352709
    [Abstract] [Full Text] [Related]

  • 10. Discovery of highly potent tubulin polymerization inhibitors: Design, synthesis, and structure-activity relationships of novel 2,7-diaryl-[1,2,4]triazolo[1,5-a]pyrimidines.
    Huo XS, Jian XE, Ou-Yang J, Chen L, Yang F, Lv DX, You WW, Rao JJ, Zhao PL.
    Eur J Med Chem; 2021 Aug 05; 220():113449. PubMed ID: 33895499
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S, An B, Li Y, Luo X, Li X, Jia X.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1769-1775. PubMed ID: 29673981
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.
    Li G, Wang Y, Li L, Ren Y, Deng X, Liu J, Wang W, Luo M, Liu S, Chen J.
    Eur J Med Chem; 2020 Sep 15; 202():112519. PubMed ID: 32650183
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis and evaluation of novel bis-substituted aromatic amide dithiocarbamate derivatives as colchicine site tubulin polymerization inhibitors with potent anticancer activities.
    Sun YX, Song J, Kong LJ, Sha BB, Tian XY, Liu XJ, Hu T, Chen P, Zhang SY.
    Eur J Med Chem; 2022 Feb 05; 229():114069. PubMed ID: 34971875
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis and biological evaluation of novel acridine and quinoline derivatives as tubulin polymerization inhibitors with anticancer activities.
    Ren Y, Ruan Y, Cheng B, Li L, Liu J, Fang Y, Chen J.
    Bioorg Med Chem; 2021 Sep 15; 46():116376. PubMed ID: 34455231
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and biological evaluation of novel thiazole-naphthalene derivatives as potential anticancer agents and tubulin polymerisation inhibitors.
    Wang G, Liu W, Fan M, He M, Li Y, Peng Z.
    J Enzyme Inhib Med Chem; 2021 Dec 15; 36(1):1694-1702. PubMed ID: 34309466
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis and biological evaluation of colchicine glycoconjugates as tubulin polymerization inhibitors.
    Wang Z, Liu R, Zhang X, Chang X, Gao M, Zhang S, Guan Q, Sun J, Zuo D, Zhang W.
    Bioorg Med Chem; 2022 Mar 15; 58():116671. PubMed ID: 35193066
    [Abstract] [Full Text] [Related]

  • 17. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents.
    Liu Y, Wei D, Zhao Y, Cheng W, Lu Y, Ma Y, Li X, Han C, Wei Y, Cao H, Zhao C.
    Bioorg Med Chem; 2012 Nov 01; 20(21):6285-95. PubMed ID: 23022053
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, biological evaluation, and structure-activity relationships of new tubulin polymerization inhibitors based on 5-amino-1,2,4-triazole scaffold.
    Yang F, Chen L, Lai JM, Jian XE, Lv DX, Yuan LL, Liu YX, Liang FT, Zheng XL, Li XL, Wei LY, You WW, Zhao PL.
    Bioorg Med Chem Lett; 2021 Apr 15; 38():127880. PubMed ID: 33636303
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and evaluation of antiproliferative and antitubulin activities of 5-methyl-4-aryl-3-(4-arylpiperazine-1-carbonyl)-4H-1,2,4-triazoles.
    Wang C, Li Y, Liu T, Wang Z, Zhang Y, Bao K, Wu Y, Guan Q, Zuo D, Zhang W.
    Bioorg Chem; 2020 Nov 15; 104():103909. PubMed ID: 33142419
    [Abstract] [Full Text] [Related]

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