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Journal Abstract Search

237 related items for PubMed ID: 33811251

  • 21. The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2.
    Croy HE, Fuller CN, Giannotti J, Robinson P, Foley AVA, Yamulla RJ, Cosgriff S, Greaves BD, von Kleeck RA, An HH, Powers CM, Tran JK, Tocker AM, Jacob KD, Davis BK, Roberts DM.
    J Biol Chem; 2016 Jun 10; 291(24):12747-12760. PubMed ID: 27068743
    [Abstract] [Full Text] [Related]

  • 22. 5-Hydroxytryptamine promotes hepatocellular carcinoma proliferation by influencing β-catenin.
    Fatima S, Shi X, Lin Z, Chen GQ, Pan XH, Wu JC, Ho JW, Lee NP, Gao H, Zhang G, Lu A, Bian ZX.
    Mol Oncol; 2016 Feb 10; 10(2):195-212. PubMed ID: 26474915
    [Abstract] [Full Text] [Related]

  • 23. TRIM65 triggers β-catenin signaling via ubiquitylation of Axin1 to promote hepatocellular carcinoma.
    Yang YF, Zhang MF, Tian QH, Zhang CZ.
    J Cell Sci; 2017 Sep 15; 130(18):3108-3115. PubMed ID: 28754688
    [Abstract] [Full Text] [Related]

  • 24. Axis inhibition protein 1 (Axin1) Deletion-Induced Hepatocarcinogenesis Requires Intact β-Catenin but Not Notch Cascade in Mice.
    Qiao Y, Wang J, Karagoz E, Liang B, Song X, Shang R, Evert K, Xu M, Che L, Evert M, Calvisi DF, Tao J, Wang B, Monga SP, Chen X.
    Hepatology; 2019 Dec 15; 70(6):2003-2017. PubMed ID: 30737831
    [Abstract] [Full Text] [Related]

  • 25. Phosphorylation of axin within biomolecular condensates counteracts its tankyrase-mediated degradation.
    Klement K, Brückner M, Bernkopf DB.
    J Cell Sci; 2023 Oct 15; 136(20):. PubMed ID: 37721093
    [Abstract] [Full Text] [Related]

  • 26. Differential effects of inactivated Axin1 and activated beta-catenin mutations in human hepatocellular carcinomas.
    Zucman-Rossi J, Benhamouche S, Godard C, Boyault S, Grimber G, Balabaud C, Cunha AS, Bioulac-Sage P, Perret C.
    Oncogene; 2007 Feb 01; 26(5):774-80. PubMed ID: 16964294
    [Abstract] [Full Text] [Related]

  • 27. Differential requirement of Hippo cascade during CTNNB1 or AXIN1 mutation-driven hepatocarcinogenesis.
    Liang B, Wang H, Qiao Y, Wang X, Qian M, Song X, Zhou Y, Zhang Y, Shang R, Che L, Chen Y, Huang Z, Wu H, Monga SP, Zeng Y, Calvisi DF, Chen X, Chen X.
    Hepatology; 2023 Jun 01; 77(6):1929-1942. PubMed ID: 35921500
    [Abstract] [Full Text] [Related]

  • 28. AXIN1 bi-allelic variants disrupting the C-terminal DIX domain cause craniometadiaphyseal osteosclerosis with hip dysplasia.
    Terhal P, Venhuizen AJ, Lessel D, Tan WH, Alswaid A, Grün R, Alzaidan HI, von Kroge S, Ragab N, Hempel M, Kubisch C, Novais E, Cristobal A, Tripolszki K, Bauer P, Fischer-Zirnsak B, Nievelstein RAJ, van Dijk A, Nikkels P, Oheim R, Hahn H, Bertoli-Avella A, Maurice MM, Kornak U.
    Am J Hum Genet; 2023 Sep 07; 110(9):1470-1481. PubMed ID: 37582359
    [Abstract] [Full Text] [Related]

  • 29. Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex.
    Li VS, Ng SS, Boersema PJ, Low TY, Karthaus WR, Gerlach JP, Mohammed S, Heck AJ, Maurice MM, Mahmoudi T, Clevers H.
    Cell; 2012 Jun 08; 149(6):1245-56. PubMed ID: 22682247
    [Abstract] [Full Text] [Related]

  • 30. A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice.
    Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S.
    Cancer Res; 2012 Jun 01; 72(11):2822-32. PubMed ID: 22440753
    [Abstract] [Full Text] [Related]

  • 31. Cripto-1 contributes to stemness in hepatocellular carcinoma by stabilizing Dishevelled-3 and activating Wnt/β-catenin pathway.
    Lo RC, Leung CO, Chan KK, Ho DW, Wong CM, Lee TK, Ng IO.
    Cell Death Differ; 2018 Aug 01; 25(8):1426-1441. PubMed ID: 29445127
    [Abstract] [Full Text] [Related]

  • 32. Blocking Wnt Secretion Reduces Growth of Hepatocellular Carcinoma Cell Lines Mostly Independent of β-Catenin Signaling.
    Wang W, Xu L, Liu P, Jairam K, Yin Y, Chen K, Sprengers D, Peppelenbosch MP, Pan Q, Smits R.
    Neoplasia; 2016 Dec 01; 18(12):711-723. PubMed ID: 27851986
    [Abstract] [Full Text] [Related]

  • 33. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.
    Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F, Michaud GA, Charlat O, Wiellette E, Zhang Y, Wiessner S, Hild M, Shi X, Wilson CJ, Mickanin C, Myer V, Fazal A, Tomlinson R, Serluca F, Shao W, Cheng H, Shultz M, Rau C, Schirle M, Schlegl J, Ghidelli S, Fawell S, Lu C, Curtis D, Kirschner MW, Lengauer C, Finan PM, Tallarico JA, Bouwmeester T, Porter JA, Bauer A, Cong F.
    Nature; 2009 Oct 01; 461(7264):614-20. PubMed ID: 19759537
    [Abstract] [Full Text] [Related]

  • 34. Tankyrase Inhibitors Target Colorectal Cancer Stem Cells via AXIN-Dependent Downregulation of c-KIT Tyrosine Kinase.
    Jang MK, Mashima T, Seimiya H.
    Mol Cancer Ther; 2020 Mar 01; 19(3):765-776. PubMed ID: 31907221
    [Abstract] [Full Text] [Related]

  • 35. Genetic alterations of Wnt signaling pathway-associated genes in hepatocellular carcinoma.
    Kim YD, Park CH, Kim HS, Choi SK, Rew JS, Kim DY, Koh YS, Jeung KW, Lee KH, Lee JS, Juhng SW, Lee JH.
    J Gastroenterol Hepatol; 2008 Jan 01; 23(1):110-8. PubMed ID: 18171349
    [Abstract] [Full Text] [Related]

  • 36. Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.
    Koirala S, Klein J, Zheng Y, Glenn NO, Eisemann T, Fon Tacer K, Miller DJ, Kulak O, Lu M, Finkelstein DB, Neale G, Tillman H, Vogel P, Strand DW, Lum L, Brautigam CA, Pascal JM, Clements WK, Potts PR.
    Cell Rep; 2020 Jul 21; 32(3):107922. PubMed ID: 32698014
    [Abstract] [Full Text] [Related]

  • 37. Conditional disruption of Axin1 leads to development of liver tumors in mice.
    Feng GJ, Cotta W, Wei XQ, Poetz O, Evans R, Jardé T, Reed K, Meniel V, Williams GT, Clarke AR, Dale TC.
    Gastroenterology; 2012 Dec 21; 143(6):1650-9. PubMed ID: 22960659
    [Abstract] [Full Text] [Related]

  • 38. Wnt signalling induces accumulation of phosphorylated β-catenin in two distinct cytosolic complexes.
    Gerlach JP, Emmink BL, Nojima H, Kranenburg O, Maurice MM.
    Open Biol; 2014 Nov 21; 4(11):140120. PubMed ID: 25392450
    [Abstract] [Full Text] [Related]

  • 39. Thr160 of Axin1 is critical for the formation and function of the β-catenin destruction complex.
    Koyama-Nasu R, Hayashi T, Nasu-Nishimura Y, Akiyama T, Yamanaka R.
    Biochem Biophys Res Commun; 2015 Apr 10; 459(3):411-5. PubMed ID: 25735981
    [Abstract] [Full Text] [Related]

  • 40. Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling.
    Zhang R, Li S, Schippers K, Li Y, Eimers B, Lavrijsen M, Wang L, Cui G, Chen X, Peppelenbosch MP, Lebbink JHG, Smits R.
    Cancer Res; 2024 May 02; 84(9):1443-1459. PubMed ID: 38359148
    [Abstract] [Full Text] [Related]

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