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Journal Abstract Search

338 related items for PubMed ID: 33820450

  • 1. Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor.
    Li J, Zou W, Yu K, Liu B, Liang W, Wang L, Lu Y, Jiang Z, Wang A, Zhu J.
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):903-913. PubMed ID: 33820450
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  • 2. Discovery of indole-2-one derivatives as BRD4 (BD1) selective inhibitors.
    Qiao XP, Wang XT, Wang S, Mu HX, Wang QS, Chen SW.
    Bioorg Med Chem; 2024 May 15; 106():117752. PubMed ID: 38749341
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  • 3. Binding pocket-based design, synthesis and biological evaluation of novel selective BRD4-BD1 inhibitors.
    Ma J, Chen H, Yang J, Yu Z, Huang P, Yang H, Zheng B, Liu R, Li Q, Hu G, Chen Z.
    Bioorg Med Chem; 2019 May 01; 27(9):1871-1881. PubMed ID: 30926312
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  • 4. Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor.
    Hu J, Wang Y, Li Y, Xu L, Cao D, Song S, Damaneh MS, Wang X, Meng T, Chen YL, Shen J, Miao Z, Xiong B.
    Eur J Med Chem; 2017 Sep 08; 137():176-195. PubMed ID: 28586718
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  • 8. Discovery of N-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744), a BET Bromodomain Inhibitor with Selectivity for the Second Bromodomain.
    Sheppard GS, Wang L, Fidanze SD, Hasvold LA, Liu D, Pratt JK, Park CH, Longenecker K, Qiu W, Torrent M, Kovar PJ, Bui M, Faivre E, Huang X, Lin X, Wilcox D, Zhang L, Shen Y, Albert DH, Magoc TJ, Rajaraman G, Kati WM, McDaniel KF.
    J Med Chem; 2020 May 28; 63(10):5585-5623. PubMed ID: 32324999
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  • 9. Computational study on the selective inhibition mechanism of MS402 to the first and second bromodomains of BRD4.
    Wang Q, Li Y, Xu J, Wang Y, Shi D, Liu L, Leung EL, Yao X.
    Proteins; 2019 Jan 28; 87(1):3-11. PubMed ID: 30260047
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  • 13. Design, synthesis and biological evaluation of indole-2-one derivatives as potent BRD4 inhibitors.
    Xu Y, Zhang XJ, Li WB, Wang XR, Wang S, Qiao XP, Chen SW.
    Eur J Med Chem; 2020 Dec 15; 208():112780. PubMed ID: 32883643
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  • 14. Synthesis and biological evaluation of indazole-4,7-dione derivatives as novel BRD4 inhibitors.
    Yoo M, Yoo M, Kim JE, Lee HK, Lee CO, Park CH, Jung KY.
    Arch Pharm Res; 2018 Jan 15; 41(1):46-56. PubMed ID: 29103140
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  • 15. Discovery of 3,5-dimethylisoxazole derivatives as novel, potent inhibitors for bromodomain and extraterminal domain (BET) family.
    Fang L, Hu Z, Yang Y, Chen P, Zhou J, Zhang H.
    Bioorg Med Chem; 2021 Jun 01; 39():116133. PubMed ID: 33862375
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