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130 related items for PubMed ID: 33824974

  • 1. Hepatocyte neogenin is required for hemojuvelin-mediated hepcidin expression and iron homeostasis in mice.
    Enns CA, Jue S, Zhang AS.
    Blood; 2021 Aug 12; 138(6):486-499. PubMed ID: 33824974
    [Abstract] [Full Text] [Related]

  • 2. Hemojuvelin-mediated hepcidin induction requires both bone morphogenetic protein type I receptors ALK2 and ALK3.
    Dogan DY, Urzica EI, Hornung I, Kastl P, Oguama D, Fette FM, Nguyen LH, Rosenbauer F, Zacharowski K, Klingmüller U, Gradhand E, von Knethen A, Popp R, Fleming I, Schrader L, Steinbicker AU.
    Blood Adv; 2024 Jun 11; 8(11):2870-2879. PubMed ID: 38588481
    [Abstract] [Full Text] [Related]

  • 3. Neogenin Facilitates the Induction of Hepcidin Expression by Hemojuvelin in the Liver.
    Zhao N, Maxson JE, Zhang RH, Wahedi M, Enns CA, Zhang AS.
    J Biol Chem; 2016 Jun 03; 291(23):12322-35. PubMed ID: 27072365
    [Abstract] [Full Text] [Related]

  • 4. Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis.
    Lee DH, Zhou LJ, Zhou Z, Xie JX, Jung JU, Liu Y, Xi CX, Mei L, Xiong WC.
    Blood; 2010 Apr 15; 115(15):3136-45. PubMed ID: 20065295
    [Abstract] [Full Text] [Related]

  • 5. Matriptase-2 suppresses hepcidin expression by cleaving multiple components of the hepcidin induction pathway.
    Wahedi M, Wortham AM, Kleven MD, Zhao N, Jue S, Enns CA, Zhang AS.
    J Biol Chem; 2017 Nov 03; 292(44):18354-18371. PubMed ID: 28924039
    [Abstract] [Full Text] [Related]

  • 6. Regulation of iron homeostasis by hepatocyte TfR1 requires HFE and contributes to hepcidin suppression in β-thalassemia.
    Xiao X, Moschetta GA, Xu Y, Fisher AL, Alfaro-Magallanes VM, Dev S, Wang CY, Babitt JL.
    Blood; 2023 Jan 26; 141(4):422-432. PubMed ID: 36322932
    [Abstract] [Full Text] [Related]

  • 7. Hemojuvelin-neogenin interaction is required for bone morphogenic protein-4-induced hepcidin expression.
    Zhang AS, Yang F, Wang J, Tsukamoto H, Enns CA.
    J Biol Chem; 2009 Aug 21; 284(34):22580-9. PubMed ID: 19564337
    [Abstract] [Full Text] [Related]

  • 8. The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo.
    Zhang AS, Gao J, Koeberl DD, Enns CA.
    J Biol Chem; 2010 May 28; 285(22):16416-23. PubMed ID: 20363739
    [Abstract] [Full Text] [Related]

  • 9. Hepcidin-mediated hypoferremic response to acute inflammation requires a threshold of Bmp6/Hjv/Smad signaling.
    Fillebeen C, Wilkinson N, Charlebois E, Katsarou A, Wagner J, Pantopoulos K.
    Blood; 2018 Oct 25; 132(17):1829-1841. PubMed ID: 30213871
    [Abstract] [Full Text] [Related]

  • 10. Matriptase-2 and Hemojuvelin in Hepcidin Regulation: In Vivo Immunoblot Studies in Mask Mice.
    Krijt J, Frýdlová J, Gurieva I, Přikryl P, Báječný M, Steinbicker AU, Vokurka M, Truksa J.
    Int J Mol Sci; 2021 Mar 06; 22(5):. PubMed ID: 33800732
    [Abstract] [Full Text] [Related]

  • 11. Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin.
    Zhang AS, Anderson SA, Meyers KR, Hernandez C, Eisenstein RS, Enns CA.
    J Biol Chem; 2007 Apr 27; 282(17):12547-56. PubMed ID: 17331953
    [Abstract] [Full Text] [Related]

  • 12. Hfe and Hjv exhibit overlapping functions for iron signaling to hepcidin.
    Kent P, Wilkinson N, Constante M, Fillebeen C, Gkouvatsos K, Wagner J, Buffler M, Becker C, Schümann K, Santos MM, Pantopoulos K.
    J Mol Med (Berl); 2015 May 27; 93(5):489-98. PubMed ID: 25609138
    [Abstract] [Full Text] [Related]

  • 13. Iron-dependent regulation of hepcidin in Hjv-/- mice: evidence that hemojuvelin is dispensable for sensing body iron levels.
    Gkouvatsos K, Fillebeen C, Daba A, Wagner J, Sebastiani G, Pantopoulos K.
    PLoS One; 2014 May 27; 9(1):e85530. PubMed ID: 24409331
    [Abstract] [Full Text] [Related]

  • 14. Hemojuvelin is essential for transferrin-dependent and transferrin-independent hepcidin expression in mice.
    Bartnikas TB, Fleming MD.
    Haematologica; 2012 Feb 27; 97(2):189-92. PubMed ID: 21993681
    [Abstract] [Full Text] [Related]

  • 15. Hepcidin downregulation by repeated bleeding is not mediated by soluble hemojuvelin.
    Krijt J, Fujikura Y, Sefc L, Vokurka M, Hlobenová T, Necas E.
    Physiol Res; 2010 Feb 27; 59(1):53-59. PubMed ID: 19249912
    [Abstract] [Full Text] [Related]

  • 16. Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis.
    Silvestri L, Pagani A, Camaschella C.
    Blood; 2008 Jan 15; 111(2):924-31. PubMed ID: 17938254
    [Abstract] [Full Text] [Related]

  • 17. Neogenin interacts with matriptase-2 to facilitate hemojuvelin cleavage.
    Enns CA, Ahmed R, Zhang AS.
    J Biol Chem; 2012 Oct 12; 287(42):35104-35117. PubMed ID: 22893705
    [Abstract] [Full Text] [Related]

  • 18. Conditional disruption of mouse HFE2 gene: maintenance of systemic iron homeostasis requires hepatic but not skeletal muscle hemojuvelin.
    Gkouvatsos K, Wagner J, Papanikolaou G, Sebastiani G, Pantopoulos K.
    Hepatology; 2011 Nov 12; 54(5):1800-7. PubMed ID: 21748766
    [Abstract] [Full Text] [Related]

  • 19. Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells.
    Zhang AS, West AP, Wyman AE, Bjorkman PJ, Enns CA.
    J Biol Chem; 2005 Oct 07; 280(40):33885-94. PubMed ID: 16103117
    [Abstract] [Full Text] [Related]

  • 20. Impaired hepcidin expression in alpha-1-antitrypsin deficiency associated with iron overload and progressive liver disease.
    Schaefer B, Haschka D, Finkenstedt A, Petersen BS, Theurl I, Henninger B, Janecke AR, Wang CY, Lin HY, Veits L, Vogel W, Weiss G, Franke A, Zoller H.
    Hum Mol Genet; 2015 Nov 01; 24(21):6254-63. PubMed ID: 26310624
    [Abstract] [Full Text] [Related]

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