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Journal Abstract Search

238 related items for PubMed ID: 33832505

  • 1. The phospholipase D inhibitor FIPI potently blocks EGF-induced calcium signaling in human breast cancer cells.
    Stricker HM, Rommerswinkel N, Keil S, Gnoth SA, Niggemann B, Dittmar T.
    Cell Commun Signal; 2021 Apr 08; 19(1):43. PubMed ID: 33832505
    [Abstract] [Full Text] [Related]

  • 2. Serum deprivation confers the MDA-MB-231 breast cancer line with an EGFR/JAK3/PLD2 system that maximizes cancer cell invasion.
    Ye Q, Kantonen S, Gomez-Cambronero J.
    J Mol Biol; 2013 Feb 22; 425(4):755-66. PubMed ID: 23238254
    [Abstract] [Full Text] [Related]

  • 3. 5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis.
    Su W, Yeku O, Olepu S, Genna A, Park JS, Ren H, Du G, Gelb MH, Morris AJ, Frohman MA.
    Mol Pharmacol; 2009 Mar 22; 75(3):437-46. PubMed ID: 19064628
    [Abstract] [Full Text] [Related]

  • 4. β-Heregulin impairs EGF induced PLC-γ1 signalling in human breast cancer cells.
    Rommerswinkel N, Keil S, Adawy A, Hengstler JG, Niggemann B, Zänker KS, Dittmar T.
    Cell Signal; 2018 Dec 22; 52():23-34. PubMed ID: 30165102
    [Abstract] [Full Text] [Related]

  • 5. Novel lipid-soluble thiol-redox antioxidant and heavy metal chelator, N,N'-bis(2-mercaptoethyl)isophthalamide (NBMI) and phospholipase D-specific inhibitor, 5-fluoro-2-indolyl des-chlorohalopemide (FIPI) attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells.
    Secor JD, Kotha SR, Gurney TO, Patel RB, Kefauver NR, Gupta N, Morris AJ, Haley BE, Parinandi NL.
    Int J Toxicol; 2011 Dec 22; 30(6):619-38. PubMed ID: 21994240
    [Abstract] [Full Text] [Related]

  • 6. The interplay of HER2/HER3/PI3K and EGFR/HER2/PLC-γ1 signalling in breast cancer cell migration and dissemination.
    Balz LM, Bartkowiak K, Andreas A, Pantel K, Niggemann B, Zänker KS, Brandt BH, Dittmar T.
    J Pathol; 2012 Jun 22; 227(2):234-44. PubMed ID: 22262199
    [Abstract] [Full Text] [Related]

  • 7. A novel role for phospholipase D as an endogenous negative regulator of platelet sensitivity.
    Elvers M, Grenegård M, Khoshjabinzadeh H, Münzer P, Borst O, Tian H, Di Paolo G, Lang F, Gawaz M, Lindahl TL, Fälker K.
    Cell Signal; 2012 Sep 22; 24(9):1743-52. PubMed ID: 22579635
    [Abstract] [Full Text] [Related]

  • 8. Critical role for the catalytic activity of phospholipase C-gamma1 in epidermal growth factor-induced cell migration.
    Xie Z, Peng J, Pennypacker SD, Chen Y.
    Biochem Biophys Res Commun; 2010 Aug 27; 399(3):425-8. PubMed ID: 20674545
    [Abstract] [Full Text] [Related]

  • 9. Two sites of action for PLD2 inhibitors: The enzyme catalytic center and an allosteric, phosphoinositide biding pocket.
    Ganesan R, Mahankali M, Alter G, Gomez-Cambronero J.
    Biochim Biophys Acta; 2015 Mar 27; 1851(3):261-72. PubMed ID: 25532944
    [Abstract] [Full Text] [Related]

  • 10. Induction of cancer cell migration by epidermal growth factor is initiated by specific phosphorylation of tyrosine 1248 of c-erbB-2 receptor via EGFR.
    Dittmar T, Husemann A, Schewe Y, Nofer JR, Niggemann B, Zänker KS, Brandt BH.
    FASEB J; 2002 Nov 27; 16(13):1823-5. PubMed ID: 12354693
    [Abstract] [Full Text] [Related]

  • 11. Reversible bleb formation in mast cells stimulated with antigen is Ca2+/calmodulin-dependent and bleb size is regulated by ARF6.
    Yanase Y, Carvou N, Frohman MA, Cockcroft S.
    Biochem J; 2009 Dec 14; 425(1):179-93. PubMed ID: 19845506
    [Abstract] [Full Text] [Related]

  • 12. Pharmacological inhibition of phospholipase D protects mice from occlusive thrombus formation and ischemic stroke--brief report.
    Stegner D, Thielmann I, Kraft P, Frohman MA, Stoll G, Nieswandt B.
    Arterioscler Thromb Vasc Biol; 2013 Sep 14; 33(9):2212-7. PubMed ID: 23868933
    [Abstract] [Full Text] [Related]

  • 13. Analysis of platelet-derived growth factor-induced phospholipase D activation in mouse embryo fibroblasts lacking phospholipase C-gamma1.
    Hess JA, Ji QS, Carpenter G, Exton JH.
    J Biol Chem; 1998 Aug 07; 273(32):20517-24. PubMed ID: 9685408
    [Abstract] [Full Text] [Related]

  • 14. EBP50 inhibits EGF-induced breast cancer cell proliferation by blocking EGFR phosphorylation.
    Yao W, Feng D, Bian W, Yang L, Li Y, Yang Z, Xiong Y, Zheng J, Zhai R, He J.
    Amino Acids; 2012 Nov 07; 43(5):2027-35. PubMed ID: 22476347
    [Abstract] [Full Text] [Related]

  • 15. Antitumour effects of PLC-gamma1-(SH2)2-TAT fusion proteins on EGFR/c-erbB-2-positive breast cancer cells.
    Katterle Y, Brandt BH, Dowdy SF, Niggemann B, Zänker KS, Dittmar T.
    Br J Cancer; 2004 Jan 12; 90(1):230-5. PubMed ID: 14710234
    [Abstract] [Full Text] [Related]

  • 16. Pulmonary fibrosis inducer, bleomycin, causes redox-sensitive activation of phospholipase D and cytotoxicity through formation of bioactive lipid signal mediator, phosphatidic acid, in lung microvascular endothelial cells.
    Patel RB, Kotha SR, Sherwani SI, Sliman SM, Gurney TO, Loar B, Butler SO, Morris AJ, Marsh CB, Parinandi NL.
    Int J Toxicol; 2011 Feb 12; 30(1):69-90. PubMed ID: 21131602
    [Abstract] [Full Text] [Related]

  • 17. Grb2 negatively regulates epidermal growth factor-induced phospholipase C-gamma1 activity through the direct interaction with tyrosine-phosphorylated phospholipase C-gamma1.
    Choi JH, Hong WP, Yun S, Kim HS, Lee JR, Park JB, Bae YS, Ryu SH, Suh PG.
    Cell Signal; 2005 Oct 12; 17(10):1289-99. PubMed ID: 16038803
    [Abstract] [Full Text] [Related]

  • 18. Structural Insights for Drugs Developed for Phospholipase D Enzymes.
    Stieglitz KA.
    Curr Drug Discov Technol; 2018 Oct 12; 15(2):81-93. PubMed ID: 28814238
    [Abstract] [Full Text] [Related]

  • 19. Chronic ethanol consumption disrupts complexation between EGF receptor and phospholipase C-gamma1: relevance to impaired hepatocyte proliferation.
    Zhang BH, Farrell GC.
    Biochem Biophys Res Commun; 1999 Apr 02; 257(1):89-94. PubMed ID: 10092515
    [Abstract] [Full Text] [Related]

  • 20. Signaling mechanisms of inhibition of phospholipase D activation by CHS-111 in formyl peptide-stimulated neutrophils.
    Chang LC, Huang TH, Chang CS, Tsai YR, Lin RH, Lee PW, Hsu MF, Huang LJ, Wang JP.
    Biochem Pharmacol; 2011 Jan 15; 81(2):269-78. PubMed ID: 20965153
    [Abstract] [Full Text] [Related]

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