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164 related items for PubMed ID: 33854565

  • 1. ATR and p-ATR are emerging prognostic biomarkers and DNA damage response targets in ovarian cancer.
    Feng W, Dean DC, Hornicek FJ, Wang J, Jia Y, Duan Z, Shi H.
    Ther Adv Med Oncol; 2020; 12():1758835920982853. PubMed ID: 33854565
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  • 2. Inhibition of ATR-Chk1 signaling blocks DNA double-strand-break repair and induces cytoplasmic vacuolization in metastatic osteosarcoma.
    Li X, Dean DC, Cote GM, Zou L, Hornicek FJ, Yu S, Duan Z.
    Ther Adv Med Oncol; 2020; 12():1758835920956900. PubMed ID: 32973933
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  • 3. Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.
    Tyagi A, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R.
    Carcinogenesis; 2005 Nov; 26(11):1978-87. PubMed ID: 15975956
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  • 4. ATR inhibition sensitizes liposarcoma to doxorubicin by increasing DNA damage.
    Cui J, Dean D, Hornicek FJ, Pollock RE, Hoffman RM, Duan Z.
    Am J Cancer Res; 2022 Nov; 12(4):1577-1592. PubMed ID: 35530299
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  • 5. ATR Inhibition Potentiates PARP Inhibitor Cytotoxicity in High Risk Neuroblastoma Cell Lines by Multiple Mechanisms.
    Southgate HED, Chen L, Tweddle DA, Curtin NJ.
    Cancers (Basel); 2020 Apr 28; 12(5):. PubMed ID: 32354033
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  • 6. Ataxia-Telangiectasia and RAD3-Related and Ataxia-Telangiectasia-Mutated Proteins in Epithelial Ovarian Carcinoma: Their Expression and Clinical Significance.
    Lee B, Lee HJ, Cho HY, Suh DH, Kim K, No JH, Kim H, Kim YB.
    Anticancer Res; 2015 Jul 28; 35(7):3909-16. PubMed ID: 26124337
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  • 8. PARP Inhibition Increases the Reliance on ATR/CHK1 Checkpoint Signaling Leading to Synthetic Lethality-An Alternative Treatment Strategy for Epithelial Ovarian Cancer Cells Independent from HR Effectiveness.
    Gralewska P, Gajek A, Marczak A, Mikuła M, Ostrowski J, Śliwińska A, Rogalska A.
    Int J Mol Sci; 2020 Dec 19; 21(24):. PubMed ID: 33352723
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  • 9. Ultrasound activates ataxia telangiectasia mutated- and rad3-related (ATR)-checkpoint kinase 1 (Chk1) pathway in human leukemia Jurkat cells.
    Furusawa Y, Iizumi T, Fujiwara Y, Hassan MA, Tabuchi Y, Nomura T, Kondo T.
    Ultrason Sonochem; 2012 Nov 19; 19(6):1246-51. PubMed ID: 22571845
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  • 10. ZEB1 inhibition sensitizes cells to the ATR inhibitor VE-821 by abrogating epithelial-mesenchymal transition and enhancing DNA damage.
    Song N, Jing W, Li C, Bai M, Cheng Y, Li H, Hou K, Li Y, Wang K, Li Z, Liu Y, Qu X, Che X.
    Cell Cycle; 2018 Nov 19; 17(5):595-604. PubMed ID: 29157079
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  • 12. Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage.
    Ha K, Fiskus W, Rao R, Balusu R, Venkannagari S, Nalabothula NR, Bhalla KN.
    Mol Cancer Ther; 2011 Jul 19; 10(7):1194-206. PubMed ID: 21566061
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  • 13. Myc is a prognostic biomarker and potential therapeutic target in osteosarcoma.
    Feng W, Dean DC, Hornicek FJ, Spentzos D, Hoffman RM, Shi H, Duan Z.
    Ther Adv Med Oncol; 2020 Jul 19; 12():1758835920922055. PubMed ID: 32426053
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  • 17. 4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway.
    Chaudhary P, Sharma R, Sahu M, Vishwanatha JK, Awasthi S, Awasthi YC.
    J Biol Chem; 2013 Jul 12; 288(28):20532-46. PubMed ID: 23733185
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