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221 related items for PubMed ID: 33865867

  • 1. Degradation of Alzheimer's Amyloid-β by a Catalytically Inactive Insulin-Degrading Enzyme.
    Sahoo BR, Panda PK, Liang W, Tang WJ, Ahuja R, Ramamoorthy A.
    J Mol Biol; 2021 Jun 25; 433(13):166993. PubMed ID: 33865867
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  • 2. Toward Allosterically Increased Catalytic Activity of Insulin-Degrading Enzyme against Amyloid Peptides.
    Kurochkin IV, Guarnera E, Wong JH, Eisenhaber F, Berezovsky IN.
    Biochemistry; 2017 Jan 10; 56(1):228-239. PubMed ID: 27982586
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  • 4. Modulation of the Activity of the Insulin-Degrading Enzyme by Aβ Peptides.
    Kemeh MM, Lazo ND.
    ACS Chem Neurosci; 2023 Aug 16; 14(16):2935-2943. PubMed ID: 37498802
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  • 8. Copper(I) and copper(II) inhibit Aβ peptides proteolysis by insulin-degrading enzyme differently: implications for metallostasis alteration in Alzheimer's disease.
    Grasso G, Pietropaolo A, Spoto G, Pappalardo G, Tundo GR, Ciaccio C, Coletta M, Rizzarelli E.
    Chemistry; 2011 Feb 25; 17(9):2752-62. PubMed ID: 21274957
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  • 9. Elucidation of interactions of Alzheimer amyloid beta peptides (Abeta40 and Abeta42) with insulin degrading enzyme: a molecular dynamics study.
    Bora RP, Prabhakar R.
    Biochemistry; 2010 May 11; 49(18):3947-56. PubMed ID: 20380468
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  • 11. Insulin-degrading enzyme in brain microvessels: proteolysis of amyloid {beta} vasculotropic variants and reduced activity in cerebral amyloid angiopathy.
    Morelli L, Llovera RE, Mathov I, Lue LF, Frangione B, Ghiso J, Castaño EM.
    J Biol Chem; 2004 Dec 31; 279(53):56004-13. PubMed ID: 15489232
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  • 12. Purified recombinant insulin-degrading enzyme degrades amyloid beta-protein but does not promote its oligomerization.
    Chesneau V, Vekrellis K, Rosner MR, Selkoe DJ.
    Biochem J; 2000 Oct 15; 351 Pt 2(Pt 2):509-16. PubMed ID: 11023838
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  • 13. Quantitative NMR Study of Insulin-Degrading Enzyme Using Amyloid-β and HIV-1 p6 Elucidates Its Chaperone Activity.
    Ramaraju B, Nelson SL, Zheng W, Ghirlando R, Deshmukh L.
    Biochemistry; 2021 Aug 24; 60(33):2519-2523. PubMed ID: 34342986
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  • 14. Characterization of insulin-degrading enzyme-mediated cleavage of Aβ in distinct aggregation states.
    Hubin E, Cioffi F, Rozenski J, van Nuland NA, Broersen K.
    Biochim Biophys Acta; 2016 Jun 24; 1860(6):1281-90. PubMed ID: 26968463
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  • 15. Insulysin: an allosteric enzyme as a target for Alzheimer's disease.
    Song ES, Hersh LB.
    J Mol Neurosci; 2005 Jun 24; 25(3):201-6. PubMed ID: 15800373
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  • 16. Somatostatin: a novel substrate and a modulator of insulin-degrading enzyme activity.
    Ciaccio C, Tundo GR, Grasso G, Spoto G, Marasco D, Ruvo M, Gioia M, Rizzarelli E, Coletta M.
    J Mol Biol; 2009 Feb 06; 385(5):1556-67. PubMed ID: 19073193
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  • 17. Multiple allosteric sites are involved in the modulation of insulin-degrading-enzyme activity by somatostatin.
    Tundo GR, Di Muzio E, Ciaccio C, Sbardella D, Di Pierro D, Polticelli F, Coletta M, Marini S.
    FEBS J; 2016 Oct 06; 283(20):3755-3770. PubMed ID: 27579517
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  • 18. Reduced amyloid-β degradation in early Alzheimer's disease but not in the APPswePS1dE9 and 3xTg-AD mouse models.
    Stargardt A, Gillis J, Kamphuis W, Wiemhoefer A, Kooijman L, Raspe M, Benckhuijsen W, Drijfhout JW, Hol EM, Reits E.
    Aging Cell; 2013 Jun 06; 12(3):499-507. PubMed ID: 23534431
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  • 19. BRI2 protein regulates β-amyloid degradation by increasing levels of secreted insulin-degrading enzyme (IDE).
    Kilger E, Buehler A, Woelfing H, Kumar S, Kaeser SA, Nagarathinam A, Walter J, Jucker M, Coomaraswamy J.
    J Biol Chem; 2011 Oct 28; 286(43):37446-57. PubMed ID: 21873424
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  • 20. Design of Peptide Substrate for Sensitively and Specifically Detecting Two Aβ-Degrading Enzymes: Neprilysin and Angiotensin-Converting Enzyme.
    Chen PT, Chen CL, Lin LT, Lo CH, Hu CJ, Chen RP, Wang SS.
    PLoS One; 2016 Oct 28; 11(4):e0153360. PubMed ID: 27096746
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