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Journal Abstract Search


198 related items for PubMed ID: 33884581

  • 1. The Antipsychotic Drug Clozapine Suppresses the RGS4 Polyubiquitylation and Proteasomal Degradation Mediated by the Arg/N-Degron Pathway.
    Jeon JH, Oh TR, Park S, Huh S, Kim JH, Mai BK, Lee JH, Kim SH, Lee MJ.
    Neurotherapeutics; 2021 Jul; 18(3):1768-1782. PubMed ID: 33884581
    [Abstract] [Full Text] [Related]

  • 2. A neurostimulant para-chloroamphetamine inhibits the arginylation branch of the N-end rule pathway.
    Jiang Y, Choi WH, Lee JH, Han DH, Kim JH, Chung YS, Kim SH, Lee MJ.
    Sci Rep; 2014 Sep 12; 4():6344. PubMed ID: 25212999
    [Abstract] [Full Text] [Related]

  • 3. N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis.
    Yoo YD, Mun SR, Ji CH, Sung KW, Kang KY, Heo AJ, Lee SH, An JY, Hwang J, Xie XQ, Ciechanover A, Kim BY, Kwon YT.
    Proc Natl Acad Sci U S A; 2018 Mar 20; 115(12):E2716-E2724. PubMed ID: 29507222
    [Abstract] [Full Text] [Related]

  • 4. Five enzymes of the Arg/N-degron pathway form a targeting complex: The concept of superchanneling.
    Oh JH, Hyun JY, Chen SJ, Varshavsky A.
    Proc Natl Acad Sci U S A; 2020 May 19; 117(20):10778-10788. PubMed ID: 32366662
    [Abstract] [Full Text] [Related]

  • 5. RGS4 is arginylated and degraded by the N-end rule pathway in vitro.
    Davydov IV, Varshavsky A.
    J Biol Chem; 2000 Jul 28; 275(30):22931-41. PubMed ID: 10783390
    [Abstract] [Full Text] [Related]

  • 6. The N-degron pathway: From basic science to therapeutic applications.
    Heo AJ, Kim SB, Kwon YT, Ji CH.
    Biochim Biophys Acta Gene Regul Mech; 2023 Jun 28; 1866(2):194934. PubMed ID: 36990317
    [Abstract] [Full Text] [Related]

  • 7. Monitoring the interactions between N-degrons and N-recognins of the Arg/N-degron pathway.
    Kwon SC, Lee J, Kwon YT, Heo AJ.
    Methods Enzymol; 2023 Jun 28; 686():165-203. PubMed ID: 37532399
    [Abstract] [Full Text] [Related]

  • 8. The arginylation branch of the N-end rule pathway positively regulates cellular autophagic flux and clearance of proteotoxic proteins.
    Jiang Y, Lee J, Lee JH, Lee JW, Kim JH, Choi WH, Yoo YD, Cha-Molstad H, Kim BY, Kwon YT, Noh SA, Kim KP, Lee MJ.
    Autophagy; 2016 Nov 28; 12(11):2197-2212. PubMed ID: 27560450
    [Abstract] [Full Text] [Related]

  • 9. The Arg/N-Degron Pathway-A Potential Running Back in Fine-Tuning the Inflammatory Response?
    Leboeuf D, Pyatkov M, Zatsepin TS, Piatkov K.
    Biomolecules; 2020 Jun 14; 10(6):. PubMed ID: 32545869
    [Abstract] [Full Text] [Related]

  • 10. RGS4 and RGS5 are in vivo substrates of the N-end rule pathway.
    Lee MJ, Tasaki T, Moroi K, An JY, Kimura S, Davydov IV, Kwon YT.
    Proc Natl Acad Sci U S A; 2005 Oct 18; 102(42):15030-5. PubMed ID: 16217033
    [Abstract] [Full Text] [Related]

  • 11. Characterization of arginylation branch of N-end rule pathway in G-protein-mediated proliferation and signaling of cardiomyocytes.
    Lee MJ, Kim DE, Zakrzewska A, Yoo YD, Kim SH, Kim ST, Seo JW, Lee YS, Dorn GW, Oh U, Kim BY, Kwon YT.
    J Biol Chem; 2012 Jul 06; 287(28):24043-52. PubMed ID: 22577142
    [Abstract] [Full Text] [Related]

  • 12. Molecular basis for ubiquitin ligase CRL2FEM1C-mediated recognition of C-degron.
    Yan X, Wang X, Li Y, Zhou M, Li Y, Song L, Mi W, Min J, Dong C.
    Nat Chem Biol; 2021 Mar 06; 17(3):263-271. PubMed ID: 33398170
    [Abstract] [Full Text] [Related]

  • 13.
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  • 14. Selectivity and anti-Parkinson's potential of thiadiazolidinone RGS4 inhibitors.
    Blazer LL, Storaska AJ, Jutkiewicz EM, Turner EM, Calcagno M, Wade SM, Wang Q, Huang XP, Traynor JR, Husbands SM, Morari M, Neubig RR.
    ACS Chem Neurosci; 2015 Jun 17; 6(6):911-9. PubMed ID: 25844489
    [Abstract] [Full Text] [Related]

  • 15. Breast cancer migration and invasion depend on proteasome degradation of regulator of G-protein signaling 4.
    Xie Y, Wolff DW, Wei T, Wang B, Deng C, Kirui JK, Jiang H, Qin J, Abel PW, Tu Y.
    Cancer Res; 2009 Jul 15; 69(14):5743-51. PubMed ID: 19549919
    [Abstract] [Full Text] [Related]

  • 16. Differential modulation of mu- and delta-opioid receptor agonists by endogenous RGS4 protein in SH-SY5Y cells.
    Wang Q, Liu-Chen LY, Traynor JR.
    J Biol Chem; 2009 Jul 03; 284(27):18357-67. PubMed ID: 19416973
    [Abstract] [Full Text] [Related]

  • 17. DHHC protein-dependent palmitoylation protects regulator of G-protein signaling 4 from proteasome degradation.
    Wang J, Xie Y, Wolff DW, Abel PW, Tu Y.
    FEBS Lett; 2010 Nov 19; 584(22):4570-4. PubMed ID: 21035448
    [Abstract] [Full Text] [Related]

  • 18. Molecular basis for arginine C-terminal degron recognition by Cul2FEM1 E3 ligase.
    Chen X, Liao S, Makaros Y, Guo Q, Zhu Z, Krizelman R, Dahan K, Tu X, Yao X, Koren I, Xu C.
    Nat Chem Biol; 2021 Mar 19; 17(3):254-262. PubMed ID: 33398168
    [Abstract] [Full Text] [Related]

  • 19. Crystal structure of the Ate1 arginyl-tRNA-protein transferase and arginylation of N-degron substrates.
    Kim BH, Kim MK, Oh SJ, Nguyen KT, Kim JH, Varshavsky A, Hwang CS, Song HK.
    Proc Natl Acad Sci U S A; 2022 Aug 02; 119(31):e2209597119. PubMed ID: 35878037
    [Abstract] [Full Text] [Related]

  • 20. N-Terminal Targeting of Regulator of G Protein Signaling Protein 2 for F-Box Only Protein 44-Mediated Proteasomal Degradation.
    McNabb HJ, Gonzalez S, Muli CS, Sjögren B.
    Mol Pharmacol; 2020 Dec 02; 98(6):677-685. PubMed ID: 33008920
    [Abstract] [Full Text] [Related]


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