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152 related items for PubMed ID: 33892370

  • 1. Testing for heterotopia formation in rats after developmental exposure to selected in vitro inhibitors of thyroperoxidase.
    Ramhøj L, Frädrich C, Svingen T, Scholze M, Wirth EK, Rijntjes E, Köhrle J, Kortenkamp A, Axelstad M.
    Environ Pollut; 2021 Aug 15; 283():117135. PubMed ID: 33892370
    [Abstract] [Full Text] [Related]

  • 2. Perinatal exposure to the thyroperoxidase inhibitors methimazole and amitrole perturbs thyroid hormone system signaling and alters motor activity in rat offspring.
    Ramhøj L, Svingen T, Frädrich C, Rijntjes E, Wirth EK, Pedersen K, Köhrle J, Axelstad M.
    Toxicol Lett; 2022 Jan 01; 354():44-55. PubMed ID: 34757178
    [Abstract] [Full Text] [Related]

  • 3. Extrapolating In Vitro Screening Assay Data for Thyroperoxidase Inhibition to Predict Serum Thyroid Hormones in the Rat.
    Hassan I, El-Masri H, Ford J, Brennan A, Handa S, Paul Friedman K, Gilbert ME.
    Toxicol Sci; 2020 Feb 01; 173(2):280-292. PubMed ID: 31697382
    [Abstract] [Full Text] [Related]

  • 4. Cross-species analysis of thyroperoxidase inhibition by xenobiotics demonstrates conservation of response between pig and rat.
    Paul KB, Hedge JM, Macherla C, Filer DL, Burgess E, Simmons SO, Crofton KM, Hornung MW.
    Toxicology; 2013 Oct 04; 312():97-107. PubMed ID: 23959146
    [Abstract] [Full Text] [Related]

  • 5. Distinct transcriptional profiles in rat thyroid glands after developmental exposure to three in vitro thyroperoxidase inhibiting chemicals.
    Rosenmai AK, Svingen T, Evrard B, Nguyen KH, Nielsen C, Axelstad M, Chalmel F, Ramhøj L.
    Genomics; 2024 Sep 04; 116(5):110938. PubMed ID: 39293535
    [Abstract] [Full Text] [Related]

  • 6. A comparison of potency differences among thyroid peroxidase (TPO) inhibitors to induce developmental toxicity and other thyroid gland-linked toxicities in humans and rats.
    Motonaga K, Ota M, Odawara K, Saito S, Welsch F.
    Regul Toxicol Pharmacol; 2016 Oct 04; 80():283-90. PubMed ID: 27350053
    [Abstract] [Full Text] [Related]

  • 7. Neurodevelopment and Thyroid Hormone Synthesis Inhibition in the Rat: Quantitative Understanding Within the Adverse Outcome Pathway Framework.
    Hassan I, El-Masri H, Kosian PA, Ford J, Degitz SJ, Gilbert ME.
    Toxicol Sci; 2017 Nov 01; 160(1):57-73. PubMed ID: 28973696
    [Abstract] [Full Text] [Related]

  • 8. Thyroid hormone-dependent formation of a subcortical band heterotopia (SBH) in the neonatal brain is not exacerbated under conditions of low dietary iron (FeD).
    Spring SR, Bastian TW, Wang Y, Kosian P, Anderson GW, Gilbert ME.
    Neurotoxicol Teratol; 2016 Nov 01; 56():41-46. PubMed ID: 27216871
    [Abstract] [Full Text] [Related]

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  • 10. Two thyroperoxidase-inhibiting chemicals induce shared transcriptional changes in hippocampus of developing rats.
    Ramhøj L, Svingen T, Evrard B, Chalmel F, Axelstad M.
    Toxicology; 2024 Jun 01; 505():153822. PubMed ID: 38685447
    [Abstract] [Full Text] [Related]

  • 11. Mechanistic Computational Model for Extrapolating In Vitro Thyroid Peroxidase (TPO) Inhibition Data to Predict Serum Thyroid Hormone Levels in Rats.
    Handa S, Hassan I, Gilbert M, El-Masri H.
    Toxicol Sci; 2021 Aug 30; 183(1):36-48. PubMed ID: 34117770
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of thyroid hormone release from cultured amphibian thyroid glands by methimazole, 6-propylthiouracil, and perchlorate.
    Hornung MW, Degitz SJ, Korte LM, Olson JM, Kosian PA, Linnum AL, Tietge JE.
    Toxicol Sci; 2010 Nov 30; 118(1):42-51. PubMed ID: 20530234
    [Abstract] [Full Text] [Related]

  • 13. The ultraviolet filter benzophenone 2 interferes with the thyroid hormone axis in rats and is a potent in vitro inhibitor of human recombinant thyroid peroxidase.
    Schmutzler C, Bacinski A, Gotthardt I, Huhne K, Ambrugger P, Klammer H, Schlecht C, Hoang-Vu C, Grüters A, Wuttke W, Jarry H, Köhrle J.
    Endocrinology; 2007 Jun 30; 148(6):2835-44. PubMed ID: 17379648
    [Abstract] [Full Text] [Related]

  • 14. Methimazole and propylthiouracil increase cellular thyroid peroxidase activity and thyroid peroxidase mRNA in cultured porcine thyroid follicles.
    Sugawara M, Sugawara Y, Wen K.
    Thyroid; 1999 May 30; 9(5):513-8. PubMed ID: 10365684
    [Abstract] [Full Text] [Related]

  • 15. Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries.
    Paul Friedman K, Watt ED, Hornung MW, Hedge JM, Judson RS, Crofton KM, Houck KA, Simmons SO.
    Toxicol Sci; 2016 May 30; 151(1):160-80. PubMed ID: 26884060
    [Abstract] [Full Text] [Related]

  • 16. Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling.
    Leonard JA, Tan YM, Gilbert M, Isaacs K, El-Masri H.
    Toxicol Sci; 2016 May 30; 151(1):57-70. PubMed ID: 26865668
    [Abstract] [Full Text] [Related]

  • 17. Coupling of iodotyrosine catalyzed by human thyroid peroxidase in vitro.
    Sugawara M.
    J Clin Endocrinol Metab; 1985 Jun 30; 60(6):1069-75. PubMed ID: 3838997
    [Abstract] [Full Text] [Related]

  • 18. Thyroid organotypic rat and human cultures used to investigate drug effects on thyroid function, hormone synthesis and release pathways.
    Vickers AE, Heale J, Sinclair JR, Morris S, Rowe JM, Fisher RL.
    Toxicol Appl Pharmacol; 2012 Apr 01; 260(1):81-8. PubMed ID: 22342233
    [Abstract] [Full Text] [Related]

  • 19. Progress towards development of an amphibian-based thyroid screening assay using Xenopus laevis. Organismal and thyroidal responses to the model compounds 6-propylthiouracil, methimazole, and thyroxine.
    Degitz SJ, Holcombe GW, Flynn KM, Kosian PA, Korte JJ, Tietge JE.
    Toxicol Sci; 2005 Oct 01; 87(2):353-64. PubMed ID: 16002479
    [Abstract] [Full Text] [Related]

  • 20. Is periventricular heterotopia a useful endpoint for developmental thyroid hormone system disruption in mouse toxicity studies?
    Ramhøj L, Guyot R, Svingen T, Kortenkamp A, Flamant F, Axelstad M.
    Regul Toxicol Pharmacol; 2023 Aug 01; 142():105445. PubMed ID: 37414127
    [Abstract] [Full Text] [Related]

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