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Journal Abstract Search

321 related items for PubMed ID: 34000483

  • 1. Structure-based discovery of potent and selective small-molecule inhibitors targeting signal transducer and activator of transcription 3 (STAT3).
    Huang Q, Zhong Y, Li B, Ouyang S, Deng L, Mo J, Shi S, Lv N, Wu R, Liu P, Hu W, Zhang X, Wang Y.
    Eur J Med Chem; 2021 Oct 05; 221():113525. PubMed ID: 34000483
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  • 2. Design, synthesis and activity of novel 2,6-disubstituted purine derivatives, potential small molecule inhibitors of signal transducer and activator of transcription 3.
    Wang X, He Q, Wu K, Guo T, Du X, Zhang H, Fang L, Zheng N, Zhang Q, Ye F.
    Eur J Med Chem; 2019 Oct 01; 179():218-232. PubMed ID: 31254923
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  • 8. Discovery, synthesis, and evaluation of small-molecule signal transducer and activator of transcription 3 inhibitors.
    Shi ZB, Zhao D, Huang YY, Du Y, Cao XR, Gong ZN, Zhao R, Li JX.
    Chem Pharm Bull (Tokyo); 2012 Oct 01; 60(12):1574-80. PubMed ID: 23207637
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  • 9. Structure-Based Discovery of SD-36 as a Potent, Selective, and Efficacious PROTAC Degrader of STAT3 Protein.
    Zhou H, Bai L, Xu R, Zhao Y, Chen J, McEachern D, Chinnaswamy K, Wen B, Dai L, Kumar P, Yang CY, Liu Z, Wang M, Liu L, Meagher JL, Yi H, Sun D, Stuckey JA, Wang S.
    J Med Chem; 2019 Dec 26; 62(24):11280-11300. PubMed ID: 31747516
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  • 12. Novel imidazopyridine suppresses STAT3 activation by targeting SHP-1.
    Su JC, Chang CH, Wu SH, Shiau CW.
    J Enzyme Inhib Med Chem; 2018 Dec 26; 33(1):1248-1255. PubMed ID: 30261753
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  • 13. Identification and characterization of small molecule inhibitors of signal transducer and activator of transcription 3 (STAT3) signaling pathway by virtual screening.
    Zhang M, Zhu W, Ding N, Zhang W, Li Y.
    Bioorg Med Chem Lett; 2013 Apr 01; 23(7):2225-9. PubMed ID: 23434226
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  • 14. Discovery of P3971 an orally efficacious novel anticancer agent targeting HIF-1α and STAT3 pathways.
    Godse P, Kumar P, Yewalkar N, Deore V, Lohar M, Mundada R, Padgaonkar A, Manohar S, Joshi A, Bhatia D, Desai N, Damre A, Bhonde M, Joshi K, Sharma R, Kumar S.
    Anticancer Agents Med Chem; 2013 Nov 01; 13(9):1460-6. PubMed ID: 24102269
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  • 16. LL1, a novel and highly selective STAT3 inhibitor, displays anti-colorectal cancer activities in vitro and in vivo.
    Liu Z, Wang H, Guan L, Lai C, Yu W, Lai M.
    Br J Pharmacol; 2020 Jan 01; 177(2):298-313. PubMed ID: 31499589
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  • 17. Pyrimethamine conjugated histone deacetylase inhibitors: Design, synthesis and evidence for triple negative breast cancer selective cytotoxicity.
    Wu B, Fathi S, Mortley S, Mohiuddin M, Jang YC, Oyelere AK.
    Bioorg Med Chem; 2020 Mar 15; 28(6):115345. PubMed ID: 32061484
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  • 18. A novel small molecule STAT3 inhibitor SLSI-1216 suppresses proliferation and tumor growth of triple-negative breast cancer cells through apoptotic induction.
    Park SK, Byun WS, Lee S, Han YT, Jeong YS, Jang K, Chung SJ, Lee J, Suh YG, Lee SK.
    Biochem Pharmacol; 2020 Aug 15; 178():114053. PubMed ID: 32450253
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  • 19. Signal Transducer and Activator of Transcription Protein 3 (STAT3): An Update on its Direct Inhibitors as Promising Anticancer Agents.
    Gelain A, Mori M, Meneghetti F, Villa S.
    Curr Med Chem; 2019 Aug 15; 26(27):5165-5206. PubMed ID: 30027840
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  • 20. Preclinical characterization of signal transducer and activator of transcription 3 small molecule inhibitors for primary and metastatic brain cancer therapy.
    Assi HH, Paran C, VanderVeen N, Savakus J, Doherty R, Petruzzella E, Hoeschele JD, Appelman H, Raptis L, Mikkelsen T, Lowenstein PR, Castro MG.
    J Pharmacol Exp Ther; 2014 Jun 15; 349(3):458-69. PubMed ID: 24696041
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