These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

136 related items for PubMed ID: 34030114

  • 21. Exploring the drug resistance of V32I and M46L mutant HIV-1 protease to inhibitor TMC114: flap dynamics and binding mechanism.
    Meher BR, Wang Y.
    J Mol Graph Model; 2015 Mar; 56():60-73. PubMed ID: 25562662
    [Abstract] [Full Text] [Related]

  • 22. Defective hydrophobic sliding mechanism and active site expansion in HIV-1 protease drug resistant variant Gly48Thr/Leu89Met: mechanisms for the loss of saquinavir binding potency.
    Goldfarb NE, Ohanessian M, Biswas S, McGee TD, Mahon BP, Ostrov DA, Garcia J, Tang Y, McKenna R, Roitberg A, Dunn BM.
    Biochemistry; 2015 Jan 20; 54(2):422-33. PubMed ID: 25513833
    [Abstract] [Full Text] [Related]

  • 23. Exploring molecular mechanism of allosteric inhibitor to relieve drug resistance of multiple mutations in HIV-1 protease by enhanced conformational sampling.
    Chen J, Peng C, Wang J, Zhu W.
    Proteins; 2018 Dec 20; 86(12):1294-1305. PubMed ID: 30260044
    [Abstract] [Full Text] [Related]

  • 24. A major role for a set of non-active site mutations in the development of HIV-1 protease drug resistance.
    Muzammil S, Ross P, Freire E.
    Biochemistry; 2003 Jan 28; 42(3):631-8. PubMed ID: 12534275
    [Abstract] [Full Text] [Related]

  • 25. Effects of drug-resistant mutations on the dynamic properties of HIV-1 protease and inhibition by Amprenavir and Darunavir.
    Yu Y, Wang J, Shao Q, Shi J, Zhu W.
    Sci Rep; 2015 May 27; 5():10517. PubMed ID: 26012849
    [Abstract] [Full Text] [Related]

  • 26. HIV-1 protease with 10 lopinavir and darunavir resistance mutations exhibits altered inhibition, structural rearrangements and extreme dynamics.
    Wong-Sam A, Wang YF, Kneller DW, Kovalevsky AY, Ghosh AK, Harrison RW, Weber IT.
    J Mol Graph Model; 2022 Dec 27; 117():108315. PubMed ID: 36108568
    [Abstract] [Full Text] [Related]

  • 27. I36T↑T mutation in South African subtype C (C-SA) HIV-1 protease significantly alters protease-drug interactions.
    Maseko SB, Padayachee E, Govender T, Sayed Y, Kruger G, Maguire GEM, Lin J.
    Biol Chem; 2017 Sep 26; 398(10):1109-1117. PubMed ID: 28525359
    [Abstract] [Full Text] [Related]

  • 28. Prediction of drug-resistance in HIV-1 subtype C based on protease sequences from ART naive and first-line treatment failures in North India using genotypic and docking analysis.
    Toor JS, Sharma A, Kumar R, Gupta P, Garg P, Arora SK.
    Antiviral Res; 2011 Nov 26; 92(2):213-8. PubMed ID: 21875619
    [Abstract] [Full Text] [Related]

  • 29. Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.
    Henes M, Lockbaum GJ, Kosovrasti K, Leidner F, Nachum GS, Nalivaika EA, Lee SK, Spielvogel E, Zhou S, Swanstrom R, Bolon DNA, Kurt Yilmaz N, Schiffer CA.
    ACS Chem Biol; 2019 Nov 15; 14(11):2441-2452. PubMed ID: 31361460
    [Abstract] [Full Text] [Related]

  • 30. Non-active site mutants of HIV-1 protease influence resistance and sensitisation towards protease inhibitors.
    Bastys T, Gapsys V, Walter H, Heger E, Doncheva NT, Kaiser R, de Groot BL, Kalinina OV.
    Retrovirology; 2020 May 19; 17(1):13. PubMed ID: 32430025
    [Abstract] [Full Text] [Related]

  • 31. Revertant mutation V48G alters conformational dynamics of highly drug resistant HIV protease PRS17.
    Burnaman SH, Kneller DW, Wang YF, Kovalevsky A, Weber IT.
    J Mol Graph Model; 2021 Nov 19; 108():108005. PubMed ID: 34419931
    [Abstract] [Full Text] [Related]

  • 32. Insights into a mutation-assisted lateral drug escape mechanism from the HIV-1 protease active site.
    Sadiq SK, Wan S, Coveney PV.
    Biochemistry; 2007 Dec 25; 46(51):14865-77. PubMed ID: 18052195
    [Abstract] [Full Text] [Related]

  • 33. Non-active site mutations in the HIV protease: Diminished drug binding affinity is achieved through modulating the hydrophobic sliding mechanism.
    Sherry D, Pandian R, Sayed Y.
    Int J Biol Macromol; 2022 Sep 30; 217():27-41. PubMed ID: 35817239
    [Abstract] [Full Text] [Related]

  • 34. Resilience to resistance of HIV-1 protease inhibitors: profile of darunavir.
    Lefebvre E, Schiffer CA.
    AIDS Rev; 2008 Sep 30; 10(3):131-42. PubMed ID: 18820715
    [Abstract] [Full Text] [Related]

  • 35. Structural and thermodynamic basis of resistance to HIV-1 protease inhibition: implications for inhibitor design.
    Velazquez-Campoy A, Muzammil S, Ohtaka H, Schön A, Vega S, Freire E.
    Curr Drug Targets Infect Disord; 2003 Dec 30; 3(4):311-28. PubMed ID: 14754432
    [Abstract] [Full Text] [Related]

  • 36. Multi-drug resistance profile of PR20 HIV-1 protease is attributed to distorted conformational and drug binding landscape: molecular dynamics insights.
    Chetty S, Bhakat S, Martin AJ, Soliman ME.
    J Biomol Struct Dyn; 2016 Dec 30; 34(1):135-51. PubMed ID: 25671669
    [Abstract] [Full Text] [Related]

  • 37. Importance of polar solvation and configurational entropy for design of antiretroviral drugs targeting HIV-1 protease.
    Kar P, Lipowsky R, Knecht V.
    J Phys Chem B; 2013 May 16; 117(19):5793-805. PubMed ID: 23614718
    [Abstract] [Full Text] [Related]

  • 38. Multidrug resistance to HIV-1 protease inhibition requires cooperative coupling between distal mutations.
    Ohtaka H, Schön A, Freire E.
    Biochemistry; 2003 Nov 25; 42(46):13659-66. PubMed ID: 14622012
    [Abstract] [Full Text] [Related]

  • 39. How Mutations Can Resist Drug Binding yet Keep HIV-1 Protease Functional.
    Appadurai R, Senapati S.
    Biochemistry; 2017 Jun 13; 56(23):2907-2920. PubMed ID: 28505418
    [Abstract] [Full Text] [Related]

  • 40. Understanding Drug Resistance of Wild-Type and L38HL Insertion Mutant of HIV-1 C Protease to Saquinavir.
    Venkatachalam S, Murlidharan N, Krishnan SR, Ramakrishnan C, Setshedi M, Pandian R, Barh D, Tiwari S, Azevedo V, Sayed Y, Gromiha MM.
    Genes (Basel); 2023 Feb 20; 14(2):. PubMed ID: 36833460
    [Abstract] [Full Text] [Related]

    Page: [Previous] [Next] [New Search]
    of 7.