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Journal Abstract Search

273 related items for PubMed ID: 34037423

  • 1. An Amino Acid Polymorphism within the HIV-1 Nef Dileucine Motif Functionally Uncouples Cell Surface CD4 and SERINC5 Downregulation.
    Mumby MJ, Johnson AL, Trothen SM, Edgar CR, Gibson R, Stathopulos PB, Arts EJ, Dikeakos JD.
    J Virol; 2021 Jul 26; 95(16):e0058821. PubMed ID: 34037423
    [Abstract] [Full Text] [Related]

  • 2. The Antagonism of HIV-1 Nef to SERINC5 Particle Infectivity Restriction Involves the Counteraction of Virion-Associated Pools of the Restriction Factor.
    Trautz B, Pierini V, Wombacher R, Stolp B, Chase AJ, Pizzato M, Fackler OT.
    J Virol; 2016 Dec 01; 90(23):10915-10927. PubMed ID: 27681140
    [Abstract] [Full Text] [Related]

  • 3. Natural HIV-1 Nef Polymorphisms Impair SERINC5 Downregulation Activity.
    Jin SW, Alsahafi N, Kuang XT, Swann SA, Toyoda M, Göttlinger H, Walker BD, Ueno T, Finzi A, Brumme ZL, Brockman MA.
    Cell Rep; 2019 Nov 05; 29(6):1449-1457.e5. PubMed ID: 31693887
    [Abstract] [Full Text] [Related]

  • 4. HIV-1 Nef Antagonizes SERINC5 Restriction by Downregulation of SERINC5 via the Endosome/Lysosome System.
    Shi J, Xiong R, Zhou T, Su P, Zhang X, Qiu X, Li H, Li S, Yu C, Wang B, Ding C, Smithgall TE, Zheng YH.
    J Virol; 2018 Jun 01; 92(11):. PubMed ID: 29514909
    [Abstract] [Full Text] [Related]

  • 5. A Conserved Acidic Residue in the C-Terminal Flexible Loop of HIV-1 Nef Contributes to the Activity of SERINC5 and CD4 Downregulation.
    Firrito C, Bertelli C, Rosa A, Chande A, Ananth S, van Dijk H, Fackler OT, Stoneham C, Singh R, Guatelli J, Pizzato M.
    Viruses; 2023 Feb 28; 15(3):. PubMed ID: 36992361
    [Abstract] [Full Text] [Related]

  • 6. AP-2 Adaptor Complex-Dependent Enhancement of HIV-1 Replication by Nef in the Absence of the Nef/AP-2 Targets SERINC5 and CD4.
    Olety B, Usami Y, Wu Y, Peters P, Göttlinger H.
    mBio; 2023 Feb 28; 14(1):e0338222. PubMed ID: 36622146
    [Abstract] [Full Text] [Related]

  • 7. Multifunctional Roles of the N-Terminal Region of HIV-1SF2Nef Are Mediated by Three Independent Protein Interaction Sites.
    Ananth S, Morath K, Trautz B, Tibroni N, Shytaj IL, Obermaier B, Stolp B, Lusic M, Fackler OT.
    J Virol; 2019 Dec 12; 94(1):. PubMed ID: 31597760
    [Abstract] [Full Text] [Related]

  • 8. Nef homodimers down-regulate SERINC5 by AP-2-mediated endocytosis to promote HIV-1 infectivity.
    Staudt RP, Smithgall TE.
    J Biol Chem; 2020 Nov 13; 295(46):15540-15552. PubMed ID: 32873704
    [Abstract] [Full Text] [Related]

  • 9. Impaired ability of Nef to counteract SERINC5 is associated with reduced plasma viremia in HIV-infected individuals.
    Toyoda M, Kamori D, Tan TS, Goebuchi K, Ohashi J, Carlson J, Kawana-Tachikawa A, Gatanaga H, Oka S, Pizzato M, Ueno T.
    Sci Rep; 2020 Nov 10; 10(1):19416. PubMed ID: 33173092
    [Abstract] [Full Text] [Related]

  • 10. Loss of Nef-mediated CD3 down-regulation in the HIV-1 lineage increases viral infectivity and spread.
    Mesner D, Hotter D, Kirchhoff F, Jolly C.
    Proc Natl Acad Sci U S A; 2020 Mar 31; 117(13):7382-7391. PubMed ID: 32179688
    [Abstract] [Full Text] [Related]

  • 11. Longitudinal within-host evolution of HIV Nef-mediated CD4, HLA and SERINC5 downregulation activity: a case study.
    Sudderuddin H, Kinloch NN, Jin SW, Miller RL, Jones BR, Brumme CJ, Joy JB, Brockman MA, Brumme ZL.
    Retrovirology; 2020 Jan 09; 17(1):3. PubMed ID: 31918727
    [Abstract] [Full Text] [Related]

  • 12. Identification of a novel binding site between HIV type 1 Nef C-terminal flexible loop and AP2 required for Nef-mediated CD4 downregulation.
    Jin YJ, Cai CY, Mezei M, Ohlmeyer M, Sanchez R, Burakoff SJ.
    AIDS Res Hum Retroviruses; 2013 Apr 09; 29(4):725-31. PubMed ID: 23151229
    [Abstract] [Full Text] [Related]

  • 13. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor.
    Bresnahan PA, Yonemoto W, Ferrell S, Williams-Herman D, Geleziunas R, Greene WC.
    Curr Biol; 1998 Nov 05; 8(22):1235-8. PubMed ID: 9811606
    [Abstract] [Full Text] [Related]

  • 14. SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef.
    Usami Y, Wu Y, Göttlinger HG.
    Nature; 2015 Oct 08; 526(7572):218-23. PubMed ID: 26416733
    [Abstract] [Full Text] [Related]

  • 15. The HIV-1 accessory proteins Nef and Vpu downregulate total and cell surface CD28 in CD4+ T cells.
    Pawlak EN, Dirk BS, Jacob RA, Johnson AL, Dikeakos JD.
    Retrovirology; 2018 Jan 12; 15(1):6. PubMed ID: 29329537
    [Abstract] [Full Text] [Related]

  • 16. Potent Enhancement of HIV-1 Replication by Nef in the Absence of SERINC3 and SERINC5.
    Wu Y, Olety B, Weiss ER, Popova E, Yamanaka H, Göttlinger H.
    mBio; 2019 Jun 11; 10(3):. PubMed ID: 31186327
    [Abstract] [Full Text] [Related]

  • 17. Characterization of Endogenous SERINC5 Protein as Anti-HIV-1 Factor.
    Passos V, Zillinger T, Casartelli N, Wachs AS, Xu S, Malassa A, Steppich K, Schilling H, Franz S, Todt D, Steinmann E, Sutter K, Dittmer U, Bohne J, Schwartz O, Barchet W, Goffinet C.
    J Virol; 2019 Dec 15; 93(24):. PubMed ID: 31597782
    [Abstract] [Full Text] [Related]

  • 18. SERINC5 Can Enhance Proinflammatory Cytokine Production by Primary Human Myeloid Cells in Response to Challenge with HIV-1 Particles.
    Pierini V, Gallucci L, Stürzel CM, Kirchhoff F, Fackler OT.
    J Virol; 2021 Apr 12; 95(9):. PubMed ID: 33597208
    [Abstract] [Full Text] [Related]

  • 19. Flow Cytometry Analysis of HIV-1 Env Conformations at the Surface of Infected Cells and Virions: Role of Nef, CD4, and SERINC5.
    Staropoli I, Dufloo J, Ducher A, Commere PH, Sartori-Rupp A, Novault S, Bruel T, Lorin V, Mouquet H, Schwartz O, Casartelli N.
    J Virol; 2020 Feb 28; 94(6):. PubMed ID: 31852789
    [Abstract] [Full Text] [Related]

  • 20. The host-cell restriction factor SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles.
    Trautz B, Wiedemann H, Lüchtenborg C, Pierini V, Kranich J, Glass B, Kräusslich HG, Brocker T, Pizzato M, Ruggieri A, Brügger B, Fackler OT.
    J Biol Chem; 2017 Aug 18; 292(33):13702-13713. PubMed ID: 28659343
    [Abstract] [Full Text] [Related]

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