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198 related items for PubMed ID: 34039628

  • 1. Mitochondrial Efflux of Citrate and Isocitrate Is Fully Dispensable for Glucose-Stimulated Insulin Secretion and Pancreatic Islet β-Cell Function.
    Bauchle CJ, Rohli KE, Boyer CK, Pal V, Rocheleau JV, Liu S, Imai Y, Taylor EB, Stephens SB.
    Diabetes; 2021 Aug; 70(8):1717-1728. PubMed ID: 34039628
    [Abstract] [Full Text] [Related]

  • 2. The dicarboxylate carrier plays a role in mitochondrial malate transport and in the regulation of glucose-stimulated insulin secretion from rat pancreatic beta cells.
    Huypens P, Pillai R, Sheinin T, Schaefer S, Huang M, Odegaard ML, Ronnebaum SM, Wettig SD, Joseph JW.
    Diabetologia; 2011 Jan; 54(1):135-45. PubMed ID: 20949348
    [Abstract] [Full Text] [Related]

  • 3. The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion.
    Joseph JW, Jensen MV, Ilkayeva O, Palmieri F, Alárcon C, Rhodes CJ, Newgard CB.
    J Biol Chem; 2006 Nov 24; 281(47):35624-32. PubMed ID: 17001083
    [Abstract] [Full Text] [Related]

  • 4. Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells.
    Ferdaoussi M, Dai X, Jensen MV, Wang R, Peterson BS, Huang C, Ilkayeva O, Smith N, Miller N, Hajmrle C, Spigelman AF, Wright RC, Plummer G, Suzuki K, Mackay JP, van de Bunt M, Gloyn AL, Ryan TE, Norquay LD, Brosnan MJ, Trimmer JK, Rolph TP, Kibbey RG, Manning Fox JE, Colmers WF, Shirihai OS, Neufer PD, Yeh ET, Newgard CB, MacDonald PE.
    J Clin Invest; 2015 Oct 01; 125(10):3847-60. PubMed ID: 26389676
    [Abstract] [Full Text] [Related]

  • 5. Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans.
    Bensellam M, Shi YC, Chan JY, Laybutt DR, Chae H, Abou-Samra M, Pappas EG, Thomas HE, Gilon P, Jonas JC.
    Diabetologia; 2019 Dec 01; 62(12):2273-2286. PubMed ID: 31624901
    [Abstract] [Full Text] [Related]

  • 6. Knockdown of both mitochondrial isocitrate dehydrogenase enzymes in pancreatic beta cells inhibits insulin secretion.
    MacDonald MJ, Brown LJ, Longacre MJ, Stoker SW, Kendrick MA, Hasan NM.
    Biochim Biophys Acta; 2013 Nov 01; 1830(11):5104-11. PubMed ID: 23876293
    [Abstract] [Full Text] [Related]

  • 7. Mitochondrial Superoxide Production Decreases on Glucose-Stimulated Insulin Secretion in Pancreatic β Cells Due to Decreasing Mitochondrial Matrix NADH/NAD+ Ratio.
    Plecitá-Hlavatá L, Engstová H, Holendová B, Tauber J, Špaček T, Petrásková L, Křen V, Špačková J, Gotvaldová K, Ježek J, Dlasková A, Smolková K, Ježek P.
    Antioxid Redox Signal; 2020 Oct 20; 33(12):789-815. PubMed ID: 32517485
    [Abstract] [Full Text] [Related]

  • 8. Control of voltage-gated potassium channel Kv2.2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion.
    Jensen MV, Haldeman JM, Zhang H, Lu D, Huising MO, Vale WW, Hohmeier HE, Rosenberg P, Newgard CB.
    J Biol Chem; 2013 Aug 09; 288(32):23128-40. PubMed ID: 23788641
    [Abstract] [Full Text] [Related]

  • 9. Feasibility of pathways for transfer of acyl groups from mitochondria to the cytosol to form short chain acyl-CoAs in the pancreatic beta cell.
    MacDonald MJ, Smith AD, Hasan NM, Sabat G, Fahien LA.
    J Biol Chem; 2007 Oct 19; 282(42):30596-606. PubMed ID: 17724028
    [Abstract] [Full Text] [Related]

  • 10. ATP synthase inhibitory factor subunit 1 regulates islet β-cell function via repression of mitochondrial homeostasis.
    Zhang K, Bao R, Huang F, Yang K, Ding Y, Lauterboeck L, Yoshida M, Long Q, Yang Q.
    Lab Invest; 2022 Jan 19; 102(1):69-79. PubMed ID: 34608240
    [Abstract] [Full Text] [Related]

  • 11. The plant product quinic acid activates Ca2+ -dependent mitochondrial function and promotes insulin secretion from pancreatic beta cells.
    Heikkilä E, Hermant A, Thevenet J, Bermont F, Kulkarni SS, Ratajczak J, Santo-Domingo J, Dioum EH, Canto C, Barron D, Wiederkehr A, De Marchi U.
    Br J Pharmacol; 2019 Sep 19; 176(17):3250-3263. PubMed ID: 31166006
    [Abstract] [Full Text] [Related]

  • 12. Acute metabolic amplification of insulin secretion in mouse islets is mediated by mitochondrial export of metabolites, but not by mitochondrial energy generation.
    Panten U, Willenborg M, Schumacher K, Hamada A, Ghaly H, Rustenbeck I.
    Metabolism; 2013 Oct 19; 62(10):1375-86. PubMed ID: 23790612
    [Abstract] [Full Text] [Related]

  • 13. Isoform-specific Roles of Prolyl Hydroxylases in the Regulation of Pancreatic β-Cell Function.
    Hoang M, Jentz E, Janssen SM, Nasteska D, Cuozzo F, Hodson DJ, Tupling AR, Fong GH, Joseph JW.
    Endocrinology; 2022 Jan 01; 163(1):. PubMed ID: 34718519
    [Abstract] [Full Text] [Related]

  • 14. Acetylation of human mitochondrial citrate carrier modulates mitochondrial citrate/malate exchange activity to sustain NADPH production during macrophage activation.
    Palmieri EM, Spera I, Menga A, Infantino V, Porcelli V, Iacobazzi V, Pierri CL, Hooper DC, Palmieri F, Castegna A.
    Biochim Biophys Acta; 2015 Aug 01; 1847(8):729-38. PubMed ID: 25917893
    [Abstract] [Full Text] [Related]

  • 15. NNT reverse mode of operation mediates glucose control of mitochondrial NADPH and glutathione redox state in mouse pancreatic β-cells.
    Santos LRB, Muller C, de Souza AH, Takahashi HK, Spégel P, Sweet IR, Chae H, Mulder H, Jonas JC.
    Mol Metab; 2017 Jun 01; 6(6):535-547. PubMed ID: 28580284
    [Abstract] [Full Text] [Related]

  • 16. Export of metabolites from pancreatic islet mitochondria as a means to study anaplerosis in insulin secretion.
    Macdonald MJ.
    Metabolism; 2003 Aug 01; 52(8):993-8. PubMed ID: 12898463
    [Abstract] [Full Text] [Related]

  • 17. Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion.
    Heart E, Cline GW, Collis LP, Pongratz RL, Gray JP, Smith PJ.
    Am J Physiol Endocrinol Metab; 2009 Jun 01; 296(6):E1354-62. PubMed ID: 19293334
    [Abstract] [Full Text] [Related]

  • 18. Regulation of glucose- and mitochondrial fuel-induced insulin secretion by a cytosolic protein histidine phosphatase in pancreatic beta-cells.
    Kamath V, Kyathanahalli CN, Jayaram B, Syed I, Olson LK, Ludwig K, Klumpp S, Krieglstein J, Kowluru A.
    Am J Physiol Endocrinol Metab; 2010 Aug 01; 299(2):E276-86. PubMed ID: 20501872
    [Abstract] [Full Text] [Related]

  • 19. The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion.
    Odegaard ML, Joseph JW, Jensen MV, Lu D, Ilkayeva O, Ronnebaum SM, Becker TC, Newgard CB.
    J Biol Chem; 2010 May 28; 285(22):16530-7. PubMed ID: 20356834
    [Abstract] [Full Text] [Related]

  • 20. Pancreatic β-cell-specific deletion of insulin-degrading enzyme leads to dysregulated insulin secretion and β-cell functional immaturity.
    Fernández-Díaz CM, Merino B, López-Acosta JF, Cidad P, de la Fuente MA, Lobatón CD, Moreno A, Leissring MA, Perdomo G, Cózar-Castellano I.
    Am J Physiol Endocrinol Metab; 2019 Nov 01; 317(5):E805-E819. PubMed ID: 31479304
    [Abstract] [Full Text] [Related]

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