These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

286 related items for PubMed ID: 34044345

  • 1. Bifunctional chiral selenium-containing 1,4-diarylazetidin-2-ones with potent antitumor activities by disrupting tubulin polymerization and inducing reactive oxygen species production.
    Tang H, Liang Y, Cheng J, Ding K, Wang Y.
    Eur J Med Chem; 2021 Oct 05; 221():113531. PubMed ID: 34044345
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors.
    Liang Y, Zhang M, Zhou P, Liu M, Li J, Wang Y.
    Bioorg Chem; 2021 Oct 05; 115():105239. PubMed ID: 34399321
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis, and biological evaluation of novel benzodiazepine derivatives as anticancer agents through inhibition of tubulin polymerization in vitro and in vivo.
    Pang Y, Lin H, Ou C, Cao Y, An B, Yan J, Li X.
    Eur J Med Chem; 2019 Nov 15; 182():111670. PubMed ID: 31499359
    [Abstract] [Full Text] [Related]

  • 4. Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect.
    Ibrahim TS, Hawwas MM, Malebari AM, Taher ES, Omar AM, Neamatallah T, Abdel-Samii ZK, Safo MK, Elshaier YAMM.
    J Enzyme Inhib Med Chem; 2021 Dec 15; 36(1):802-818. PubMed ID: 33730937
    [Abstract] [Full Text] [Related]

  • 5. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 6. Discovery of a chiral fluorinated azetidin-2-one as a tubulin polymerisation inhibitor with potent antitumour efficacy.
    Tang H, Cheng J, Liang Y, Wang Y.
    Eur J Med Chem; 2020 Jul 01; 197():112323. PubMed ID: 32339854
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and Biochemical Evaluation of 3-Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents.
    Greene TF, Wang S, Greene LM, Nathwani SM, Pollock JK, Malebari AM, McCabe T, Twamley B, O'Boyle NM, Zisterer DM, Meegan MJ.
    J Med Chem; 2016 Jan 14; 59(1):90-113. PubMed ID: 26680364
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
    Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y.
    Eur J Med Chem; 2018 Jan 20; 144():817-842. PubMed ID: 29306206
    [Abstract] [Full Text] [Related]

  • 9. Discovery of novel tubulin/HDAC dual-targeting inhibitors with strong antitumor and antiangiogenic potency.
    Wang Y, Sun M, Wang Y, Qin J, Zhang Y, Pang Y, Yao Y, Yang H, Duan Y.
    Eur J Med Chem; 2021 Dec 05; 225():113790. PubMed ID: 34454126
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S, An B, Li Y, Luo X, Li X, Jia X.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1769-1775. PubMed ID: 29673981
    [Abstract] [Full Text] [Related]

  • 11. Novel diaryl-2H-azirines: Antitumor hybrids for dual-targeting tubulin and DNA.
    Lin S, Liang Y, Cheng J, Pan F, Wang Y.
    Eur J Med Chem; 2021 Mar 15; 214():113256. PubMed ID: 33581556
    [Abstract] [Full Text] [Related]

  • 12. Synthesis, anticancer activity and molecular docking studies on 1,2-diarylbenzimidazole analogues as anti-tubulin agents.
    Zhang YL, Yang R, Xia LY, Man RJ, Chu YC, Jiang AQ, Wang ZC, Zhu HL.
    Bioorg Chem; 2019 Nov 15; 92():103219. PubMed ID: 31476616
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis and biological evaluation of vinyl selenone derivatives as novel microtubule polymerization inhibitors.
    Zhu H, Sun H, Liu Y, Duan Y, Liu J, Yang X, Li W, Qin S, Xu S, Zhu Z, Xu J.
    Eur J Med Chem; 2020 Dec 01; 207():112716. PubMed ID: 32853870
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.
    Li G, Wang Y, Li L, Ren Y, Deng X, Liu J, Wang W, Luo M, Liu S, Chen J.
    Eur J Med Chem; 2020 Sep 15; 202():112519. PubMed ID: 32650183
    [Abstract] [Full Text] [Related]

  • 15. Identification of gallic acid based glycoconjugates as a novel tubulin polymerization inhibitors.
    Upadhyaya K, Hamidullah, Singh K, Arun A, Shukla M, Srivastava N, Ashraf R, Sharma A, Mahar R, Shukla SK, Sarkar J, Ramachandran R, Lal J, Konwar R, Tripathi RP.
    Org Biomol Chem; 2016 Jan 28; 14(4):1338-58. PubMed ID: 26659548
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis of combretastatin A-4 piperazine derivatives as potential antitumor agents by inhibiting tubulin polymerization and inducing autophagy in HCT116 cells.
    Zhang H, Li M, Zhou X, Tang L, Chen G, Zhang Y.
    Eur J Med Chem; 2024 Jun 05; 272():116497. PubMed ID: 38759453
    [Abstract] [Full Text] [Related]

  • 17. Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors.
    Cao D, Liu Y, Yan W, Wang C, Bai P, Wang T, Tang M, Wang X, Yang Z, Ma B, Ma L, Lei L, Wang F, Xu B, Zhou Y, Yang T, Chen L.
    J Med Chem; 2016 Jun 23; 59(12):5721-39. PubMed ID: 27213819
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
    [Abstract] [Full Text] [Related]

  • 19. Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors.
    Yang F, He CP, Diao PC, Hong KH, Rao JJ, Zhao PL.
    Bioorg Med Chem Lett; 2019 Jan 01; 29(1):22-27. PubMed ID: 30448234
    [Abstract] [Full Text] [Related]

  • 20. Discovery of novel amide derivatives against VEGFR-2/tubulin with potent antitumor and antiangiogenic activity.
    Liu Z, Mao S, Li H, Liu W, Tao J, Lu Y, Dong H, Zhang J, Song C, Duan Y, Yao Y.
    Bioorg Chem; 2024 Oct 01; 151():107679. PubMed ID: 39094510
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 15.