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233 related items for PubMed ID: 34054727

  • 1. GRK Inhibition Potentiates Glucagon-Like Peptide-1 Action.
    Lee SP, Qi J, Xu G, Rankin MM, Littrell J, Xu JZ, Bakaj I, Pocai A.
    Front Endocrinol (Lausanne); 2021; 12():652628. PubMed ID: 34054727
    [Abstract] [Full Text] [Related]

  • 2. The role of G protein-coupled receptor kinases in GLP-1R β-arrestin recruitment and internalisation.
    McNeill SM, Lu J, Marion C Carino C, Inoue A, Zhao P, Sexton PM, Wootten D.
    Biochem Pharmacol; 2024 Apr; 222():116119. PubMed ID: 38461904
    [Abstract] [Full Text] [Related]

  • 3. New screening strategy and analysis for identification of allosteric modulators for glucagon-like peptide-1 receptor using GLP-1 (9-36) amide.
    Nakane A, Gotoh Y, Ichihara J, Nagata H.
    Anal Biochem; 2015 Dec 15; 491():23-30. PubMed ID: 26341912
    [Abstract] [Full Text] [Related]

  • 4. Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells.
    Zhang M, Robitaille M, Showalter AD, Huang X, Liu Y, Bhattacharjee A, Willard FS, Han J, Froese S, Wei L, Gaisano HY, Angers S, Sloop KW, Dai FF, Wheeler MB.
    Mol Cell Proteomics; 2014 Nov 15; 13(11):3049-62. PubMed ID: 25044020
    [Abstract] [Full Text] [Related]

  • 5. The GIP receptor displays higher basal activity than the GLP-1 receptor but does not recruit GRK2 or arrestin3 effectively.
    Al-Sabah S, Al-Fulaij M, Shaaban G, Ahmed HA, Mann RJ, Donnelly D, Bünemann M, Krasel C.
    PLoS One; 2014 Nov 15; 9(9):e106890. PubMed ID: 25191754
    [Abstract] [Full Text] [Related]

  • 6. Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles.
    Bueno AB, Showalter AD, Wainscott DB, Stutsman C, Marín A, Ficorilli J, Cabrera O, Willard FS, Sloop KW.
    J Biol Chem; 2016 May 13; 291(20):10700-15. PubMed ID: 26975372
    [Abstract] [Full Text] [Related]

  • 7. GRK2 regulates GLP-1R-mediated early phase insulin secretion in vivo.
    Arcones AC, Vila-Bedmar R, Mirasierra M, Cruces-Sande M, Vallejo M, Jones B, Tomas A, Mayor F, Murga C.
    BMC Biol; 2021 Mar 03; 19(1):40. PubMed ID: 33658023
    [Abstract] [Full Text] [Related]

  • 8. Engineered beta-cells secreting dipeptidyl peptidase IV-resistant glucagon-like peptide-1 show enhanced glucose-responsiveness.
    Islam MS, Rahman SA, Mirzaei Z, Islam KB.
    Life Sci; 2005 Jan 28; 76(11):1239-48. PubMed ID: 15642594
    [Abstract] [Full Text] [Related]

  • 9. Effects of long-term dipeptidyl peptidase-IV inhibition on body composition and glucose tolerance in high fat diet-fed mice.
    Liu X, Harada N, Yamane S, Kitajima L, Uchida S, Hamasaki A, Mukai E, Toyoda K, Yamada C, Yamada Y, Seino Y, Inagaki N.
    Life Sci; 2009 Jun 19; 84(25-26):876-81. PubMed ID: 19358859
    [Abstract] [Full Text] [Related]

  • 10. Elimination of glucagon-like peptide 1R signaling does not modify weight gain and islet adaptation in mice with combined disruption of leptin and GLP-1 action.
    Scrocchi LA, Hill ME, Saleh J, Perkins B, Drucker DJ.
    Diabetes; 2000 Sep 19; 49(9):1552-60. PubMed ID: 10969840
    [Abstract] [Full Text] [Related]

  • 11. Potentiation of insulin secretion and improvement of glucose intolerance by combining a novel G protein-coupled receptor 40 agonist DS-1558 with glucagon-like peptide-1 receptor agonists.
    Nakashima R, Yano T, Ogawa J, Tanaka N, Toda N, Yoshida M, Takano R, Inoue M, Honda T, Kume S, Matsumoto K.
    Eur J Pharmacol; 2014 Aug 15; 737():194-201. PubMed ID: 24858371
    [Abstract] [Full Text] [Related]

  • 12. Intestinal regulation of urinary sodium excretion and the pathophysiology of diabetic kidney disease: a focus on glucagon-like peptide 1 and dipeptidyl peptidase 4.
    Vallon V, Docherty NG.
    Exp Physiol; 2014 Sep 15; 99(9):1140-5. PubMed ID: 25085841
    [Abstract] [Full Text] [Related]

  • 13. Stapled, Long-Acting Xenopus GLP-1-Based Dual GLP-1/Glucagon Receptor Agonists with Potent Therapeutic Efficacy for Metabolic Disease.
    Han C, Sun Y, Yang Q, Zhou F, Chen X, Wu L, Sun L, Han J.
    Mol Pharm; 2021 Aug 02; 18(8):2906-2923. PubMed ID: 34240881
    [Abstract] [Full Text] [Related]

  • 14. Absence of the glucagon-like peptide-1 receptor does not affect the metabolic phenotype of mice with liver-specific G(s)α deficiency.
    Chen M, Mema E, Kelleher J, Nemechek N, Berger A, Wang J, Xie T, Gavrilova O, Drucker DJ, Weinstein LS.
    Endocrinology; 2011 Sep 02; 152(9):3343-50. PubMed ID: 21771891
    [Abstract] [Full Text] [Related]

  • 15. Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1.
    Hager MV, Clydesdale L, Gellman SH, Sexton PM, Wootten D.
    Biochem Pharmacol; 2017 Jul 15; 136():99-108. PubMed ID: 28363772
    [Abstract] [Full Text] [Related]

  • 16. Second extracellular loop of human glucagon-like peptide-1 receptor (GLP-1R) has a critical role in GLP-1 peptide binding and receptor activation.
    Koole C, Wootten D, Simms J, Miller LJ, Christopoulos A, Sexton PM.
    J Biol Chem; 2012 Feb 03; 287(6):3642-58. PubMed ID: 22147710
    [Abstract] [Full Text] [Related]

  • 17. Beta-arrestin2 as a competitor for GRK2 interaction with the GLP-1 receptor upon receptor activation.
    Jorgensen R, Norklit Roed S, Heding A, Elling CE.
    Pharmacology; 2011 Feb 03; 88(3-4):174-81. PubMed ID: 21952200
    [Abstract] [Full Text] [Related]

  • 18. Neprilysin inhibition in mouse islets enhances insulin secretion in a GLP-1 receptor dependent manner.
    Esser N, Barrow BM, Choung E, Shen NJ, Zraika S.
    Islets; 2018 Feb 03; 10(5):175-180. PubMed ID: 30142012
    [Abstract] [Full Text] [Related]

  • 19. Differential impact of amino acid substitutions on critical residues of the human glucagon-like peptide-1 receptor involved in peptide activity and small-molecule allostery.
    Koole C, Wootten D, Simms J, Miller LJ, Christopoulos A, Sexton PM.
    J Pharmacol Exp Ther; 2015 Apr 03; 353(1):52-63. PubMed ID: 25630467
    [Abstract] [Full Text] [Related]

  • 20. Glucagon-like peptide-1: regulation of insulin secretion and therapeutic potential.
    Gromada J, Brock B, Schmitz O, Rorsman P.
    Basic Clin Pharmacol Toxicol; 2004 Dec 03; 95(6):252-62. PubMed ID: 15569269
    [Abstract] [Full Text] [Related]


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