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240 related items for PubMed ID: 34093851

  • 1. A novel cell-penetrating peptide targeting calpain-cleavage of PSD-95 induced by excitotoxicity improves neurological outcome after stroke.
    Ayuso-Dolado S, Esteban-Ortega GM, Vidaurre ÓG, Díaz-Guerra M.
    Theranostics; 2021; 11(14):6746-6765. PubMed ID: 34093851
    [Abstract] [Full Text] [Related]

  • 2. PSD-95: An Effective Target for Stroke Therapy Using Neuroprotective Peptides.
    Ugalde-Triviño L, Díaz-Guerra M.
    Int J Mol Sci; 2021 Nov 22; 22(22):. PubMed ID: 34830481
    [Abstract] [Full Text] [Related]

  • 3. Development of a neuroprotective peptide that preserves survival pathways by preventing Kidins220/ARMS calpain processing induced by excitotoxicity.
    Gamir-Morralla A, López-Menéndez C, Ayuso-Dolado S, Tejeda GS, Montaner J, Rosell A, Iglesias T, Díaz-Guerra M.
    Cell Death Dis; 2015 Oct 22; 6(10):e1939. PubMed ID: 26492372
    [Abstract] [Full Text] [Related]

  • 4. Prevention of excitotoxicity-induced processing of BDNF receptor TrkB-FL leads to stroke neuroprotection.
    Tejeda GS, Esteban-Ortega GM, San Antonio E, Vidaurre ÓG, Díaz-Guerra M.
    EMBO Mol Med; 2019 Jul 22; 11(7):e9950. PubMed ID: 31273936
    [Abstract] [Full Text] [Related]

  • 5. Excitotoxicity and focal cerebral ischemia induce truncation of the NR2A and NR2B subunits of the NMDA receptor and cleavage of the scaffolding protein PSD-95.
    Gascón S, Sobrado M, Roda JM, Rodríguez-Peña A, Díaz-Guerra M.
    Mol Psychiatry; 2008 Jan 22; 13(1):99-114. PubMed ID: 17486105
    [Abstract] [Full Text] [Related]

  • 6. Memantine attenuates cell apoptosis by suppressing the calpain-caspase-3 pathway in an experimental model of ischemic stroke.
    Chen B, Wang G, Li W, Liu W, Lin R, Tao J, Jiang M, Chen L, Wang Y.
    Exp Cell Res; 2017 Feb 15; 351(2):163-172. PubMed ID: 28069373
    [Abstract] [Full Text] [Related]

  • 7. N-Terminomic Changes in Neurons During Excitotoxicity Reveal Proteolytic Events Associated With Synaptic Dysfunctions and Potential Targets for Neuroprotection.
    Ameen SS, Griem-Krey N, Dufour A, Hossain MI, Hoque A, Sturgeon S, Nandurkar H, Draxler DF, Medcalf RL, Kamaruddin MA, Lucet IS, Leeming MG, Liu D, Dhillon A, Lim JP, Basheer F, Zhu HJ, Bokhari L, Roulston CL, Paradkar PN, Kleifeld O, Clarkson AN, Wellendorph P, Ciccotosto GD, Williamson NA, Ang CS, Cheng HC.
    Mol Cell Proteomics; 2023 May 15; 22(5):100543. PubMed ID: 37030595
    [Abstract] [Full Text] [Related]

  • 8. Calpain-Mediated Degradation of Drebrin by Excitotoxicity In vitro and In vivo.
    Chimura T, Launey T, Yoshida N.
    PLoS One; 2015 May 15; 10(4):e0125119. PubMed ID: 25905636
    [Abstract] [Full Text] [Related]

  • 9. A truncated fragment of Src protein kinase generated by calpain-mediated cleavage is a mediator of neuronal death in excitotoxicity.
    Hossain MI, Roulston CL, Kamaruddin MA, Chu PWY, Ng DCH, Dusting GJ, Bjorge JD, Williamson NA, Fujita DJ, Cheung SN, Chan TO, Hill AF, Cheng HC.
    J Biol Chem; 2013 Apr 05; 288(14):9696-9709. PubMed ID: 23400779
    [Abstract] [Full Text] [Related]

  • 10. Interactions of postsynaptic density-95 and the NMDA receptor 2 subunit control calpain-mediated cleavage of the NMDA receptor.
    Dong YN, Waxman EA, Lynch DR.
    J Neurosci; 2004 Dec 08; 24(49):11035-45. PubMed ID: 15590920
    [Abstract] [Full Text] [Related]

  • 11. Calpain-mediated degradation of PSD-95 in developing and adult rat brain.
    Lu X, Rong Y, Baudry M.
    Neurosci Lett; 2000 Jun 02; 286(2):149-53. PubMed ID: 10825658
    [Abstract] [Full Text] [Related]

  • 12. The mechanism of taurine protection against endoplasmic reticulum stress in an animal stroke model of cerebral artery occlusion and stroke-related conditions in primary neuronal cell culture.
    Gharibani PM, Modi J, Pan C, Menzie J, Ma Z, Chen PC, Tao R, Prentice H, Wu JY.
    Adv Exp Med Biol; 2013 Jun 02; 776():241-58. PubMed ID: 23392887
    [Abstract] [Full Text] [Related]

  • 13. Melatonin improves neuroplasticity by upregulating the growth-associated protein-43 (GAP-43) and NMDAR postsynaptic density-95 (PSD-95) proteins in cultured neurons exposed to glutamate excitotoxicity and in rats subjected to transient focal cerebral ischemia even during a long-term recovery period.
    Juan WS, Huang SY, Chang CC, Hung YC, Lin YW, Chen TY, Lee AH, Lee AC, Wu TS, Lee EJ.
    J Pineal Res; 2014 Mar 02; 56(2):213-23. PubMed ID: 24350898
    [Abstract] [Full Text] [Related]

  • 14. Brain ischaemia induces shedding of a BDNF-scavenger ectodomain from TrkB receptors by excitotoxicity activation of metalloproteinases and γ-secretases.
    Tejeda GS, Ayuso-Dolado S, Arbeteta R, Esteban-Ortega GM, Vidaurre OG, Díaz-Guerra M.
    J Pathol; 2016 Apr 02; 238(5):627-40. PubMed ID: 26712630
    [Abstract] [Full Text] [Related]

  • 15. Protection of neuronal cells from excitotoxicity by disrupting nNOS-PSD95 interaction with a small molecule SCR-4026.
    Mo SF, Liao GY, Yang J, Wang MY, Hu Y, Lian GN, Kong LD, Zhao Y.
    Brain Res; 2016 Oct 01; 1648(Pt A):250-256. PubMed ID: 27421179
    [Abstract] [Full Text] [Related]

  • 16. P38 MAPK is involved in enhanced NMDA receptor-dependent excitotoxicity in YAC transgenic mouse model of Huntington disease.
    Fan J, Gladding CM, Wang L, Zhang LY, Kaufman AM, Milnerwood AJ, Raymond LA.
    Neurobiol Dis; 2012 Mar 01; 45(3):999-1009. PubMed ID: 22198502
    [Abstract] [Full Text] [Related]

  • 17. Neuronal Rho GTPase Rac1 elimination confers neuroprotection in a mouse model of permanent ischemic stroke.
    Karabiyik C, Fernandes R, Figueiredo FR, Socodato R, Brakebusch C, Lambertsen KL, Relvas JB, Santos SD.
    Brain Pathol; 2018 Jul 01; 28(4):569-580. PubMed ID: 28960571
    [Abstract] [Full Text] [Related]

  • 18. Imbalance of neurotrophin receptor isoforms TrkB-FL/TrkB-T1 induces neuronal death in excitotoxicity.
    Vidaurre OG, Gascón S, Deogracias R, Sobrado M, Cuadrado E, Montaner J, Rodríguez-Peña A, Díaz-Guerra M.
    Cell Death Dis; 2012 Jan 19; 3(1):e256. PubMed ID: 22258407
    [Abstract] [Full Text] [Related]

  • 19. Excitotoxic targeting of Kidins220 to the Golgi apparatus precedes calpain cleavage of Rap1-activation complexes.
    López-Menéndez C, Simón-García A, Gamir-Morralla A, Pose-Utrilla J, Luján R, Mochizuki N, Díaz-Guerra M, Iglesias T.
    Cell Death Dis; 2019 Jul 11; 10(7):535. PubMed ID: 31296845
    [Abstract] [Full Text] [Related]

  • 20. Calpain-cleaved collapsin response mediator protein-3 induces neuronal death after glutamate toxicity and cerebral ischemia.
    Hou ST, Jiang SX, Desbois A, Huang D, Kelly J, Tessier L, Karchewski L, Kappler J.
    J Neurosci; 2006 Feb 22; 26(8):2241-9. PubMed ID: 16495451
    [Abstract] [Full Text] [Related]

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