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Journal Abstract Search

382 related items for PubMed ID: 34119830

  • 1. Design, synthesis and evaluation of new quinazolin-4-one derivatives as apoptotic enhancers and autophagy inhibitors with potent antitumor activity.
    ElZahabi HSA, Nafie MS, Osman D, Elghazawy NH, Soliman DH, El-Helby AAH, Arafa RK.
    Eur J Med Chem; 2021 Oct 15; 222():113609. PubMed ID: 34119830
    [Abstract] [Full Text] [Related]

  • 2. New thieno[3,2-d]pyrimidine-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents, EGFR and ARO inhibitors inducing apoptosis in breast cancer cells.
    Farghaly AM, AboulWafa OM, Baghdadi HH, Abd El Razik HA, Sedra SMY, Shamaa MM.
    Bioorg Chem; 2021 Oct 15; 115():105208. PubMed ID: 34365057
    [Abstract] [Full Text] [Related]

  • 3. Quinazolin-4(3H)-one based potential multiple tyrosine kinase inhibitors with excellent cytotoxicity.
    Mirgany TO, Abdalla AN, Arifuzzaman M, Motiur Rahman AFM, Al-Salem HS.
    J Enzyme Inhib Med Chem; 2021 Dec 15; 36(1):2055-2067. PubMed ID: 34551654
    [Abstract] [Full Text] [Related]

  • 4. Quinazoline Based HSP90 Inhibitors: Synthesis, Modeling Study and ADME Calculations Towards Breast Cancer Targeting.
    El-Shafey HW, Gomaa RM, El-Messery SM, Goda FE.
    Bioorg Med Chem Lett; 2020 Aug 01; 30(15):127281. PubMed ID: 32527460
    [Abstract] [Full Text] [Related]

  • 5. Design and synthesis of thienopyrimidine urea derivatives with potential cytotoxic and pro-apoptotic activity against breast cancer cell line MCF-7.
    Abdelhaleem EF, Abdelhameid MK, Kassab AE, Kandeel MM.
    Eur J Med Chem; 2018 Jan 01; 143():1807-1825. PubMed ID: 29133058
    [Abstract] [Full Text] [Related]

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  • 7. Design, synthesis, and biological evaluation of novel 6-(pyridin-3-yl) quinazolin-4(3H)-one derivatives as potential anticancer agents via PI3K inhibition.
    Yang H, Li Q, Su M, Luo F, Liu Y, Wang D, Fan Y.
    Bioorg Med Chem; 2021 Sep 15; 46():116346. PubMed ID: 34403956
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  • 9. Design, synthesis and assessment of new series of quinazolinone derivatives as EGFR inhibitors along with their cytotoxic evaluation against MCF7 and A549 cancer cell lines.
    Aziz MW, Kamal AM, Mohamed KO, Elgendy AA.
    Bioorg Med Chem Lett; 2021 Jun 01; 41():127987. PubMed ID: 33771586
    [Abstract] [Full Text] [Related]

  • 10. EGFR/VEGFR-2 dual inhibitor and apoptotic inducer: Design, synthesis, anticancer activity and docking study of new 2-thioxoimidazolidin-4one derivatives.
    Mourad AAE, Farouk NA, El-Sayed EH, Mahdy ARE.
    Life Sci; 2021 Jul 15; 277():119531. PubMed ID: 33887348
    [Abstract] [Full Text] [Related]

  • 11. Novel pyrazole-based COX-2 inhibitors as potential anticancer agents: Design, synthesis, cytotoxic effect against resistant cancer cells, cell cycle arrest, apoptosis induction and dual EGFR/Topo-1 inhibition.
    Halim PA, Sharkawi SMZ, Labib MB.
    Bioorg Chem; 2023 Feb 15; 131():106273. PubMed ID: 36444790
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and anticancer activity of N-substituted 2-arylquinazolinones bearing trans-stilbene scaffold.
    Mahdavi M, Pedrood K, Safavi M, Saeedi M, Pordeli M, Ardestani SK, Emami S, Adib M, Foroumadi A, Shafiee A.
    Eur J Med Chem; 2015 May 05; 95():492-9. PubMed ID: 25847767
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis and in vitro biological evaluation of quinazolinone derivatives as EGFR inhibitors for antitumor treatment.
    Le Y, Gan Y, Fu Y, Liu J, Li W, Zou X, Zhou Z, Wang Z, Ouyang G, Yan L.
    J Enzyme Inhib Med Chem; 2020 Dec 05; 35(1):555-564. PubMed ID: 31967481
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis, and molecular docking studies of 2-(furan-2-yl)quinazolin-4-one derivatives as potential antiproliferative agents.
    Ahmed MF, Belal A.
    Arch Pharm (Weinheim); 2015 Jul 05; 348(7):487-97. PubMed ID: 25921702
    [Abstract] [Full Text] [Related]

  • 15. Pyridazino[1,6-b]quinazolinones as new anticancer scaffold: Synthesis, DNA intercalation, topoisomerase I inhibition and antitumor evaluation in vitro and in vivo.
    Huang WY, Zhang XR, Lyu L, Wang SQ, Zhang XT.
    Bioorg Chem; 2020 Jun 05; 99():103814. PubMed ID: 32278208
    [Abstract] [Full Text] [Related]

  • 16. Discovery of new quinazolin-4(3H)-ones as VEGFR-2 inhibitors: Design, synthesis, and anti-proliferative evaluation.
    Eissa IH, El-Helby AA, Mahdy HA, Khalifa MM, Elnagar HA, Mehany ABM, Metwaly AM, Elhendawy MA, Radwan MM, ElSohly MA, El-Adl K.
    Bioorg Chem; 2020 Dec 05; 105():104380. PubMed ID: 33128967
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and molecular docking studies of thymol based 1,2,3-triazole hybrids as thymidylate synthase inhibitors and apoptosis inducers against breast cancer cells.
    Alam MM, Malebari AM, Syed N, Neamatallah T, Almalki ASA, Elhenawy AA, Obaid RJ, Alsharif MA.
    Bioorg Med Chem; 2021 May 15; 38():116136. PubMed ID: 33894490
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and molecular docking study of new pyrimidine-based hydrazones with selective anti-proliferative activity against MCF-7 and MDA-MB-231 human breast cancer cell lines.
    Badawi WA, Samir M, Fathy HM, Okda TM, Noureldin MH, Atwa GMK, AboulWafa OM.
    Bioorg Chem; 2023 Sep 15; 138():106610. PubMed ID: 37210828
    [Abstract] [Full Text] [Related]

  • 19. EGFR inhibitors and apoptotic inducers: Design, synthesis, anticancer activity and docking studies of novel xanthine derivatives carrying chalcone moiety as hybrid molecules.
    Abou-Zied HA, Youssif BGM, Mohamed MFA, Hayallah AM, Abdel-Aziz M.
    Bioorg Chem; 2019 Aug 15; 89():102997. PubMed ID: 31136902
    [Abstract] [Full Text] [Related]

  • 20. Novel thienopyrimidine derivatives as dual EGFR and VEGFR-2 inhibitors: design, synthesis, anticancer activity and effect on cell cycle profile.
    Mghwary AE, Gedawy EM, Kamal AM, Abuel-Maaty SM.
    J Enzyme Inhib Med Chem; 2019 Dec 15; 34(1):838-852. PubMed ID: 30919701
    [Abstract] [Full Text] [Related]

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