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209 related items for PubMed ID: 34166557

  • 1. Active Rap1-mediated inhibition of choroidal neovascularization requires interactions with IQGAP1 in choroidal endothelial cells.
    Ramshekar A, Wang H, Kunz E, Pappas C, Hageman GS, Chaqour B, Sacks DB, Hartnett ME.
    FASEB J; 2021 Jul; 35(7):e21642. PubMed ID: 34166557
    [Abstract] [Full Text] [Related]

  • 2. IQGAP1 causes choroidal neovascularization by sustaining VEGFR2-mediated Rac1 activation.
    Wang H, Ramshekar A, Kunz E, Sacks DB, Hartnett ME.
    Angiogenesis; 2020 Nov; 23(4):685-698. PubMed ID: 32783108
    [Abstract] [Full Text] [Related]

  • 3. Rap1 GTPase Inhibits Tumor Necrosis Factor-α-Induced Choroidal Endothelial Migration via NADPH Oxidase- and NF-κB-Dependent Activation of Rac1.
    Wang H, Fotheringham L, Wittchen ES, Hartnett ME.
    Am J Pathol; 2015 Dec; 185(12):3316-25. PubMed ID: 26476350
    [Abstract] [Full Text] [Related]

  • 4. Thy-1 Regulates VEGF-Mediated Choroidal Endothelial Cell Activation and Migration: Implications in Neovascular Age-Related Macular Degeneration.
    Wang H, Han X, Kunz E, Hartnett ME.
    Invest Ophthalmol Vis Sci; 2016 Oct 01; 57(13):5525-5534. PubMed ID: 27768790
    [Abstract] [Full Text] [Related]

  • 5. Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo.
    Wittchen ES, Nishimura E, McCloskey M, Wang H, Quilliam LA, Chrzanowska-Wodnicka M, Hartnett ME.
    PLoS One; 2013 Oct 01; 8(9):e73070. PubMed ID: 24039860
    [Abstract] [Full Text] [Related]

  • 6. Activation of Rap1 inhibits NADPH oxidase-dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization.
    Wang H, Jiang Y, Shi D, Quilliam LA, Chrzanowska-Wodnicka M, Wittchen ES, Li DY, Hartnett ME.
    FASEB J; 2014 Jan 01; 28(1):265-74. PubMed ID: 24043260
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  • 8. Regulation of signaling events involved in the pathophysiology of neovascular AMD.
    Wang H, Hartnett ME.
    Mol Vis; 2016 Jan 01; 22():189-202. PubMed ID: 27013848
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  • 11. IQGAP1 binds Rap1 and modulates its activity.
    Jeong HW, Li Z, Brown MD, Sacks DB.
    J Biol Chem; 2007 Jul 13; 282(28):20752-62. PubMed ID: 17517894
    [Abstract] [Full Text] [Related]

  • 12. Optimal Inhibition of Choroidal Neovascularization by scAAV2 with VMD2 Promoter-driven Active Rap1a in the RPE.
    Wang H, Kunz E, Stoddard GJ, Hauswirth WW, Hartnett ME.
    Sci Rep; 2019 Oct 31; 9(1):15732. PubMed ID: 31673119
    [Abstract] [Full Text] [Related]

  • 13. Crosstalk Between RPE Cells and Choroidal Endothelial Cells via the ANXA1/FPR2/SHP2/NLRP3 Inflammasome/Pyroptosis Axis Promotes Choroidal Neovascularization.
    Zhu M, Wang Y, Zhu L, Du S, Wang Z, Zhang Y, Guo Y, Tu Y, Song E.
    Inflammation; 2022 Feb 31; 45(1):414-427. PubMed ID: 34595678
    [Abstract] [Full Text] [Related]

  • 14. Decorin inhibits angiogenic potential of choroid-retinal endothelial cells by downregulating hypoxia-induced Met, Rac1, HIF-1α and VEGF expression in cocultured retinal pigment epithelial cells.
    Du S, Wang S, Wu Q, Hu J, Li T.
    Exp Eye Res; 2013 Nov 31; 116():151-60. PubMed ID: 24016866
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  • 16. Inhibition of YAP ameliorates choroidal neovascularization via inhibiting endothelial cell proliferation.
    Yan Z, Shi H, Zhu R, Li L, Qin B, Kang L, Chen H, Guan H.
    Mol Vis; 2018 Nov 31; 24():83-93. PubMed ID: 29422766
    [Abstract] [Full Text] [Related]

  • 17. 7-ketocholesterol induces endothelial-mesenchymal transition and promotes fibrosis: implications in neovascular age-related macular degeneration and treatment.
    Wang H, Ramshekar A, Kunz E, Hartnett ME.
    Angiogenesis; 2021 Aug 31; 24(3):583-595. PubMed ID: 33646466
    [Abstract] [Full Text] [Related]

  • 18. Choroidal endothelial cells transmigrate across the retinal pigment epithelium but do not proliferate in response to soluble vascular endothelial growth factor.
    Geisen P, McColm JR, Hartnett ME.
    Exp Eye Res; 2006 Apr 31; 82(4):608-19. PubMed ID: 16259980
    [Abstract] [Full Text] [Related]

  • 19. The role of vascular endothelial growth factor-induced activation of NADPH oxidase in choroidal endothelial cells and choroidal neovascularization.
    Monaghan-Benson E, Hartmann J, Vendrov AE, Budd S, Byfield G, Parker A, Ahmad F, Huang W, Runge M, Burridge K, Madamanchi N, Hartnett ME.
    Am J Pathol; 2010 Oct 31; 177(4):2091-102. PubMed ID: 20802176
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  • 20. Heterotypic RPE-choroidal endothelial cell contact increases choroidal endothelial cell transmigration via PI 3-kinase and Rac1.
    Peterson LJ, Wittchen ES, Geisen P, Burridge K, Hartnett ME.
    Exp Eye Res; 2007 Apr 31; 84(4):737-44. PubMed ID: 17292356
    [Abstract] [Full Text] [Related]

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