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Journal Abstract Search

216 related items for PubMed ID: 34175541

  • 1. Design, synthesis and biological evaluation of indole-based [1,2,4]triazolo[4,3-a] pyridine derivatives as novel microtubule polymerization inhibitors.
    Wu CJ, Wu JQ, Hu Y, Pu S, Lin Y, Zeng Z, Hu J, Chen WH.
    Eur J Med Chem; 2021 Nov 05; 223():113629. PubMed ID: 34175541
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V, Pindiprolu SKSS, Sana S, Ramamurty DSVNM, Madasi JRK, Vadlamani S.
    Anticancer Agents Med Chem; 2021 Nov 05; 21(8):1047-1055. PubMed ID: 32981511
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis and anticancer properties of isocombretapyridines as potent colchicine binding site inhibitors.
    Shuai W, Li X, Li W, Xu F, Lu L, Yao H, Yang L, Zhu H, Xu S, Zhu Z, Xu J.
    Eur J Med Chem; 2020 Jul 01; 197():112308. PubMed ID: 32339853
    [Abstract] [Full Text] [Related]

  • 4. Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities.
    Yang F, Yu LZ, Diao PC, Jian XE, Zhou MF, Jiang CS, You WW, Ma WF, Zhao PL.
    Bioorg Chem; 2019 Nov 01; 92():103260. PubMed ID: 31525523
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and biological evaluation of 1-benzyl-N-(2-(phenylamino)pyridin-3-yl)-1H-1,2,3-triazole-4-carboxamides as antimitotic agents.
    Prasad B, Lakshma Nayak V, Srikanth PS, Baig MF, Subba Reddy NV, Babu KS, Kamal A.
    Bioorg Chem; 2019 Mar 01; 83():535-548. PubMed ID: 30472555
    [Abstract] [Full Text] [Related]

  • 6. 3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization.
    Romagnoli R, Prencipe F, Oliva P, Baraldi S, Baraldi PG, Brancale A, Ferla S, Hamel E, Bortolozzi R, Viola G.
    Bioorg Chem; 2018 Oct 01; 80():361-374. PubMed ID: 29986184
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and Biological Evaluation of 1-Methyl-1H-indole-Pyrazoline Hybrids as Potential Tubulin Polymerization Inhibitors.
    Zhang YL, Qin YJ, Tang DJ, Yang MR, Li BY, Wang YT, Cai HY, Wang BZ, Zhu HL.
    ChemMedChem; 2016 Jul 05; 11(13):1446-58. PubMed ID: 27159418
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and biological evaluation of novel indole-pyrimidine hybrids bearing morpholine and thiomorpholine moieties.
    Diao PC, Li Q, Hu MJ, Ma YF, You WW, Hong KH, Zhao PL.
    Eur J Med Chem; 2017 Jul 07; 134():110-118. PubMed ID: 28410492
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and biological evaluation of novel shikonin-benzo[b]furan derivatives as tubulin polymerization inhibitors targeting the colchicine binding site.
    Shao YY, Yin Y, Lian BP, Leng JF, Xia YZ, Kong LY.
    Eur J Med Chem; 2020 Mar 15; 190():112105. PubMed ID: 32035399
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and structure-activity relationships of 5-phenyloxazole-2-carboxylic acid derivatives as novel inhibitors of tubulin polymerization.
    Zhang R, Mo H, Ma YY, Zhao DG, Zhang K, Zhang T, Chen X, Zheng X.
    Bioorg Med Chem Lett; 2021 May 15; 40():127968. PubMed ID: 33753264
    [Abstract] [Full Text] [Related]

  • 11. Development of triazolothiadiazine derivatives as highly potent tubulin polymerization inhibitors: Structure-activity relationship, in vitro and in vivo study.
    Ma W, Chen P, Huo X, Ma Y, Li Y, Diao P, Yang F, Zheng S, Hu M, You W, Zhao P.
    Eur J Med Chem; 2020 Dec 15; 208():112847. PubMed ID: 33022479
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis, and biological evaluation of new series of pyrrol-2(3H)-one and pyridazin-3(2H)-one derivatives as tubulin polymerization inhibitors.
    Abdelbaset MS, Abdelrahman MH, Bukhari SNA, Gouda AM, Youssif BGM, Abdel-Aziz M, Abuo-Rahma GEA.
    Bioorg Chem; 2021 Feb 15; 107():104522. PubMed ID: 33317838
    [Abstract] [Full Text] [Related]

  • 13. Synthesis, Anticancer Activity and Molecular Modeling Studies of Novel Chalcone Derivatives Containing Indole and Naphthalene Moieties as Tubulin Polymerization Inhibitors.
    Wang G, Peng Z, Li Y.
    Chem Pharm Bull (Tokyo); 2019 Jul 01; 67(7):725-728. PubMed ID: 30982797
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis and bioevaluation of 2,7-diaryl-pyrazolo[1,5-a]pyrimidines as tubulin polymerization inhibitors.
    Liu R, Zhang S, Huang M, Guo Z, Li L, Li M, Wu L, Guan Q, Zhang W.
    Bioorg Chem; 2021 Oct 01; 115():105220. PubMed ID: 34352709
    [Abstract] [Full Text] [Related]

  • 15. Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.
    Alswah M, Bayoumi AH, Elgamal K, Elmorsy A, Ihmaid S, Ahmed HEA.
    Molecules; 2017 Dec 27; 23(1):. PubMed ID: 29280968
    [Abstract] [Full Text] [Related]

  • 16. Design and synthesis of imidazo[2,1-b]thiazole-chalcone conjugates: microtubule-destabilizing agents.
    Kamal A, Balakrishna M, Nayak VL, Shaik TB, Faazil S, Nimbarte VD.
    ChemMedChem; 2014 Dec 27; 9(12):2766-80. PubMed ID: 25313981
    [Abstract] [Full Text] [Related]

  • 17. Synthesis, biological evaluation, and molecular docking studies of novel 1-benzene acyl-2-(1-methylindol-3-yl)-benzimidazole derivatives as potential tubulin polymerization inhibitors.
    Wang YT, Qin YJ, Yang N, Zhang YL, Liu CH, Zhu HL.
    Eur J Med Chem; 2015 Jun 24; 99():125-37. PubMed ID: 26070164
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
    Qin YJ, Li YJ, Jiang AQ, Yang MR, Zhu QZ, Dong H, Zhu HL.
    Eur J Med Chem; 2015 Apr 13; 94():447-57. PubMed ID: 25828827
    [Abstract] [Full Text] [Related]

  • 19. Design and synthesis of substituted dihydropyrimidinone derivatives as cytotoxic and tubulin polymerization inhibitors.
    Sana S, Tokala R, Bajaj DM, Nagesh N, Bokara KK, Kiranmai G, Lakshmi UJ, Vadlamani S, Talla V, Shankaraiah N.
    Bioorg Chem; 2019 Dec 13; 93():103317. PubMed ID: 31586714
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and biological evaluation of indole-2-carbohydrazides and thiazolidinyl-indole-2-carboxamides as potent tubulin polymerization inhibitors.
    Kazan F, Yagci ZB, Bai R, Ozkirimli E, Hamel E, Ozkirimli S.
    Comput Biol Chem; 2019 Jun 13; 80():512-523. PubMed ID: 31185422
    [Abstract] [Full Text] [Related]

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