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Journal Abstract Search

270 related items for PubMed ID: 34176786

  • 21. Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice.
    Liskiewicz A, Khalil A, Liskiewicz D, Novikoff A, Grandl G, Maity-Kumar G, Gutgesell RM, Bakhti M, Bastidas-Ponce A, Czarnecki O, Makris K, Lickert H, Feuchtinger A, Tost M, Coupland C, Ständer L, Akindehin S, Prakash S, Abrar F, Castelino RL, He Y, Knerr PJ, Yang B, Hogendorf WFJ, Zhang S, Hofmann SM, Finan B, DiMarchi RD, Tschöp MH, Douros JD, Müller TD.
    Nat Metab; 2023 Dec; 5(12):2075-2085. PubMed ID: 37946085
    [Abstract] [Full Text] [Related]

  • 22. An oral GLP-1 and GIP dual receptor agonist improves metabolic disorders in high fat-fed mice.
    Ma T, Lu W, Wang Y, Qian P, Tian H, Gao X, Yao W.
    Eur J Pharmacol; 2022 Jan 05; 914():174635. PubMed ID: 34800466
    [Abstract] [Full Text] [Related]

  • 23. Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models.
    Killion EA, Wang J, Yie J, Shi SD, Bates D, Min X, Komorowski R, Hager T, Deng L, Atangan L, Lu SC, Kurzeja RJM, Sivits G, Lin J, Chen Q, Wang Z, Thibault SA, Abbott CM, Meng T, Clavette B, Murawsky CM, Foltz IN, Rottman JB, Hale C, Véniant MM, Lloyd DJ.
    Sci Transl Med; 2018 Dec 19; 10(472):. PubMed ID: 30567927
    [Abstract] [Full Text] [Related]

  • 24. Differential effects of glucose-dependent insulinotropic polypeptide receptor/glucagon-like peptide-1 receptor heteromerization on cell signaling when expressed in HEK-293 cells.
    Al-Zaid B, Chacko S, Ezeamuzie CI, Bünemann M, Krasel C, Karimian T, Lanzerstorfer P, Al-Sabah S.
    Pharmacol Res Perspect; 2022 Oct 19; 10(5):e01013. PubMed ID: 36177761
    [Abstract] [Full Text] [Related]

  • 25. Design of novel therapeutics targeting the glucose-dependent insulinotropic polypeptide receptor (GIPR) to aid weight loss.
    Davies I, Tan TMM.
    Expert Opin Drug Discov; 2023 Jun 19; 18(6):659-669. PubMed ID: 37154171
    [Abstract] [Full Text] [Related]

  • 26. GIP-derived GIP receptor antagonists - a review of their role in GIP receptor pharmacology.
    Rosenkilde MM, Lindquist P, Kizilkaya HS, Gasbjerg LS.
    Peptides; 2024 Jul 19; 177():171212. PubMed ID: 38608836
    [Abstract] [Full Text] [Related]

  • 27. A Dual GLP-1/GIP Receptor Agonist Does Not Antagonize Glucagon at Its Receptor but May Act as a Biased Agonist at the GLP-1 Receptor.
    Al-Zamel N, Al-Sabah S, Luqmani Y, Adi L, Chacko S, Schneider TD, Krasel C.
    Int J Mol Sci; 2019 Jul 19; 20(14):. PubMed ID: 31330984
    [Abstract] [Full Text] [Related]

  • 28. Cardiovascular biology of the GIP receptor.
    Greenwell AA, Chahade JJ, Ussher JR.
    Peptides; 2020 Mar 19; 125():170228. PubMed ID: 31812593
    [Abstract] [Full Text] [Related]

  • 29. Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes.
    Kizilkaya HS, Sørensen KV, Madsen JS, Lindquist P, Douros JD, Bork-Jensen J, Berghella A, Gerlach PA, Gasbjerg LS, Mokrosiński J, Mowery SA, Knerr PJ, Finan B, Campbell JE, D'Alessio DA, Perez-Tilve D, Faas F, Mathiasen S, Rungby J, Sørensen HT, Vaag A, Nielsen JS, Holm JC, Lauenborg J, Damm P, Pedersen O, Linneberg A, Hartmann B, Holst JJ, Hansen T, Wright SC, Lauschke VM, Grarup N, Hauser AS, Rosenkilde MM.
    Nat Metab; 2024 Jul 19; 6(7):1268-1281. PubMed ID: 38871982
    [Abstract] [Full Text] [Related]

  • 30. Targeting glucose-dependent insulinotropic polypeptide receptor for neurodegenerative disorders.
    Verma MK, Goel R, Krishnadas N, Nemmani KVS.
    Expert Opin Ther Targets; 2018 Jul 19; 22(7):615-628. PubMed ID: 29911915
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  • 32. Tyr1 and Ile7 of glucose-dependent insulinotropic polypeptide (GIP) confer differential ligand selectivity toward GIP and glucagon-like peptide-1 receptors.
    Moon MJ, Kim HY, Kim SG, Park J, Choi DS, Hwang JI, Seong JY.
    Mol Cells; 2010 Aug 19; 30(2):149-54. PubMed ID: 20799012
    [Abstract] [Full Text] [Related]

  • 33. Chronic peptide-based GIP receptor inhibition exhibits modest glucose metabolic changes in mice when administered either alone or combined with GLP-1 agonism.
    West JA, Tsakmaki A, Ghosh SS, Parkes DG, Grønlund RV, Pedersen PJ, Maggs D, Rajagopalan H, Bewick GA.
    PLoS One; 2021 Aug 19; 16(3):e0249239. PubMed ID: 33788878
    [Abstract] [Full Text] [Related]

  • 34. LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept.
    Coskun T, Urva S, Roell WC, Qu H, Loghin C, Moyers JS, O'Farrell LS, Briere DA, Sloop KW, Thomas MK, Pirro V, Wainscott DB, Willard FS, Abernathy M, Morford L, Du Y, Benson C, Gimeno RE, Haupt A, Milicevic Z.
    Cell Metab; 2022 Sep 06; 34(9):1234-1247.e9. PubMed ID: 35985340
    [Abstract] [Full Text] [Related]

  • 35. Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors.
    Zhao F, Zhou Q, Cong Z, Hang K, Zou X, Zhang C, Chen Y, Dai A, Liang A, Ming Q, Wang M, Chen LN, Xu P, Chang R, Feng W, Xia T, Zhang Y, Wu B, Yang D, Zhao L, Xu HE, Wang MW.
    Nat Commun; 2022 Feb 25; 13(1):1057. PubMed ID: 35217653
    [Abstract] [Full Text] [Related]

  • 36. Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor.
    Regmi A, Aihara E, Christe ME, Varga G, Beyer TP, Ruan X, Beebe E, O'Farrell LS, Bellinger MA, Austin AK, Lin Y, Hu H, Konkol DL, Wojnicki S, Holland AK, Friedrich JL, Brown RA, Estelle AS, Badger HS, Gaidosh GS, Kooijman S, Rensen PCN, Coskun T, Thomas MK, Roell W.
    Cell Metab; 2024 Jul 02; 36(7):1534-1549.e7. PubMed ID: 38878772
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  • 40. Evidence for Involvement of GIP and GLP-1 Receptors and the Gut-Gonadal Axis in Regulating Female Reproductive Function in Mice.
    Khan D, Ojo OO, Woodward OR, Lewis JE, Sridhar A, Gribble FM, Reimann F, Flatt PR, Moffett RC.
    Biomolecules; 2022 Nov 23; 12(12):. PubMed ID: 36551163
    [Abstract] [Full Text] [Related]

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