These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

234 related items for PubMed ID: 34201418

  • 1. Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening.
    Zhou Q, Guo W, Dai A, Cai X, Vass M, de Graaf C, Shui W, Zhao S, Yang D, Wang MW.
    Biomolecules; 2021 Jun 23; 11(7):. PubMed ID: 34201418
    [Abstract] [Full Text] [Related]

  • 2. Discovery of a potential positive allosteric modulator of glucagon-like peptide 1 receptor through virtual screening and experimental study.
    Redij T, Ma J, Li Z, Hua X, Li Z.
    J Comput Aided Mol Des; 2019 Nov 23; 33(11):973-981. PubMed ID: 31758355
    [Abstract] [Full Text] [Related]

  • 3. New screening strategy and analysis for identification of allosteric modulators for glucagon-like peptide-1 receptor using GLP-1 (9-36) amide.
    Nakane A, Gotoh Y, Ichihara J, Nagata H.
    Anal Biochem; 2015 Dec 15; 491():23-30. PubMed ID: 26341912
    [Abstract] [Full Text] [Related]

  • 4. Structural Determinants of Binding the Seven-transmembrane Domain of the Glucagon-like Peptide-1 Receptor (GLP-1R).
    Yang D, de Graaf C, Yang L, Song G, Dai A, Cai X, Feng Y, Reedtz-Runge S, Hanson MA, Yang H, Jiang H, Stevens RC, Wang MW.
    J Biol Chem; 2016 Jun 17; 291(25):12991-3004. PubMed ID: 27059958
    [Abstract] [Full Text] [Related]

  • 5. A Duplexed High-Throughput Screen to Identify Allosteric Modulators of the Glucagon-Like Peptide 1 and Glucagon Receptors.
    Morris LC, Days EL, Turney M, Mi D, Lindsley CW, Weaver CD, Niswender KD.
    J Biomol Screen; 2014 Jul 17; 19(6):847-58. PubMed ID: 24525870
    [Abstract] [Full Text] [Related]

  • 6. Discovery of small molecule positive allosteric modulators of the secretin receptor.
    Dengler DG, Harikumar KG, Pollari S, Sun Q, Brown BT, Shinoki-Iwaya A, Ardecky R, Miller LJ, Sergienko EA.
    Biochem Pharmacol; 2021 Mar 17; 185():114451. PubMed ID: 33545115
    [Abstract] [Full Text] [Related]

  • 7. Ligand-Receptor Interactions and Machine Learning in GCGR and GLP-1R Drug Discovery.
    Mizera M, Latek D.
    Int J Mol Sci; 2021 Apr 14; 22(8):. PubMed ID: 33920024
    [Abstract] [Full Text] [Related]

  • 8. Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles.
    Bueno AB, Showalter AD, Wainscott DB, Stutsman C, Marín A, Ficorilli J, Cabrera O, Willard FS, Sloop KW.
    J Biol Chem; 2016 May 13; 291(20):10700-15. PubMed ID: 26975372
    [Abstract] [Full Text] [Related]

  • 9. Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators.
    Song G, Yang D, Wang Y, de Graaf C, Zhou Q, Jiang S, Liu K, Cai X, Dai A, Lin G, Liu D, Wu F, Wu Y, Zhao S, Ye L, Han GW, Lau J, Wu B, Hanson MA, Liu ZJ, Wang MW, Stevens RC.
    Nature; 2017 Jun 08; 546(7657):312-315. PubMed ID: 28514449
    [Abstract] [Full Text] [Related]

  • 10.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 11. Structural insights into probe-dependent positive allosterism of the GLP-1 receptor.
    Bueno AB, Sun B, Willard FS, Feng D, Ho JD, Wainscott DB, Showalter AD, Vieth M, Chen Q, Stutsman C, Chau B, Ficorilli J, Agejas FJ, Cumming GR, Jiménez A, Rojo I, Kobilka TS, Kobilka BK, Sloop KW.
    Nat Chem Biol; 2020 Oct 08; 16(10):1105-1110. PubMed ID: 32690941
    [Abstract] [Full Text] [Related]

  • 12. An Overview, Advantages and Therapeutic Potential of Nonpeptide Positive Allosteric Modulators of Glucagon-Like Peptide-1 Receptor.
    Smelcerovic A, Lazarevic J, Tomovic K, Anastasijevic M, Jukic M, Kocic G, Anderluh M.
    ChemMedChem; 2019 Mar 05; 14(5):514-521. PubMed ID: 30609277
    [Abstract] [Full Text] [Related]

  • 13. Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site.
    Wang J, Yang D, Cheng X, Yang L, Wang Z, Dai A, Cai X, Zhang C, Yuliantie E, Liu Q, Jiang H, Liu H, Wang MW, Yang H.
    ACS Chem Biol; 2021 Nov 19; 16(11):2444-2452. PubMed ID: 34570476
    [Abstract] [Full Text] [Related]

  • 14. Strategies for the identification of allosteric modulators of G-protein-coupled receptors.
    Burford NT, Watson J, Bertekap R, Alt A.
    Biochem Pharmacol; 2011 Mar 15; 81(6):691-702. PubMed ID: 21184747
    [Abstract] [Full Text] [Related]

  • 15. Repositioning Dequalinium as Potent Muscarinic Allosteric Ligand by Combining Virtual Screening Campaigns and Experimental Binding Assays.
    Mazzolari A, Gervasoni S, Pedretti A, Fumagalli L, Matucci R, Vistoli G.
    Int J Mol Sci; 2020 Aug 19; 21(17):. PubMed ID: 32825082
    [Abstract] [Full Text] [Related]

  • 16. Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor.
    Cong Z, Chen LN, Ma H, Zhou Q, Zou X, Ye C, Dai A, Liu Q, Huang W, Sun X, Wang X, Xu P, Zhao L, Xia T, Zhong W, Yang D, Eric Xu H, Zhang Y, Wang MW.
    Nat Commun; 2021 Jun 18; 12(1):3763. PubMed ID: 34145245
    [Abstract] [Full Text] [Related]

  • 17. Accelerated structure-based design of chemically diverse allosteric modulators of a muscarinic G protein-coupled receptor.
    Miao Y, Goldfeld DA, Moo EV, Sexton PM, Christopoulos A, McCammon JA, Valant C.
    Proc Natl Acad Sci U S A; 2016 Sep 20; 113(38):E5675-84. PubMed ID: 27601651
    [Abstract] [Full Text] [Related]

  • 18. Identification of a novel allosteric GLP-1R antagonist HTL26119 using structure- based drug design.
    O'Brien A, Andrews SP, Baig AH, Bortolato A, Brown AJH, Brown GA, Brown SH, Christopher JA, Congreve M, Cooke RM, De Graaf C, Errey JC, Fieldhouse C, Jazayeri A, Marshall FH, Mason JS, Mobarec JC, Okrasa K, Steele KN, Southall SM, Teobald I, Watson SP, Weir M.
    Bioorg Med Chem Lett; 2019 Oct 15; 29(20):126611. PubMed ID: 31447084
    [Abstract] [Full Text] [Related]

  • 19. Design and preparation of the class B G protein-coupled receptors GLP-1R and GCGR for 19 F-NMR studies in solution.
    Wang H, Hu W, Liu D, Wüthrich K.
    FEBS J; 2021 Jul 15; 288(13):4053-4063. PubMed ID: 33369025
    [Abstract] [Full Text] [Related]

  • 20. Role of the Second Extracellular Loop of the Adenosine A1 Receptor on Allosteric Modulator Binding, Signaling, and Cooperativity.
    Nguyen AT, Vecchio EA, Thomas T, Nguyen TD, Aurelio L, Scammells PJ, White PJ, Sexton PM, Gregory KJ, May LT, Christopoulos A.
    Mol Pharmacol; 2016 Dec 15; 90(6):715-725. PubMed ID: 27683013
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 12.