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Journal Abstract Search

285 related items for PubMed ID: 34217977

  • 1. Cyanobiphenyls: Novel H3 receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease.
    Godyń J, Zaręba P, Łażewska D, Stary D, Reiner-Link D, Frank A, Latacz G, Mogilski S, Kaleta M, Doroz-Płonka A, Lubelska A, Honkisz-Orzechowska E, Olejarz-Maciej A, Handzlik J, Stark H, Kieć-Kononowicz K, Malawska B, Bajda M.
    Bioorg Chem; 2021 Sep; 114():105129. PubMed ID: 34217977
    [Abstract] [Full Text] [Related]

  • 2. Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of Alzheimer's disease.
    Łażewska D, Bajda M, Kaleta M, Zaręba P, Doroz-Płonka A, Siwek A, Alachkar A, Mogilski S, Saad A, Kuder K, Olejarz-Maciej A, Godyń J, Stary D, Sudoł S, Więcek M, Latacz G, Walczak M, Handzlik J, Sadek B, Malawska B, Kieć-Kononowicz K.
    Eur J Med Chem; 2020 Dec 01; 207():112743. PubMed ID: 32882609
    [Abstract] [Full Text] [Related]

  • 3. Biphenylalkoxyamine Derivatives-Histamine H3 Receptor Ligands with Butyrylcholinesterase Inhibitory Activity.
    Łażewska D, Zaręba P, Godyń J, Doroz-Płonka A, Frank A, Reiner-Link D, Bajda M, Stary D, Mogilski S, Olejarz-Maciej A, Kaleta M, Stark H, Malawska B, Kieć-Kononowicz K.
    Molecules; 2021 Jun 11; 26(12):. PubMed ID: 34208297
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and pharmacological evaluation of donepezil-based agents as new cholinesterase/monoamine oxidase inhibitors for the potential application against Alzheimer's disease.
    Li F, Wang ZM, Wu JJ, Wang J, Xie SS, Lan JS, Xu W, Kong LY, Wang XB.
    J Enzyme Inhib Med Chem; 2016 Jun 11; 31(sup3):41-53. PubMed ID: 27384289
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and biological evaluation of 3,4-dihydro-2(1H)-quinoline-O-alkylamine derivatives as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
    Sang Z, Pan W, Wang K, Ma Q, Yu L, Liu W.
    Bioorg Med Chem; 2017 Jun 15; 25(12):3006-3017. PubMed ID: 28487125
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis, in-silico and biological evaluation of novel chalcone-O-carbamate derivatives as multifunctional agents for the treatment of Alzheimer's disease.
    Sang Z, Wang K, Shi J, Liu W, Tan Z.
    Eur J Med Chem; 2019 Sep 15; 178():726-739. PubMed ID: 31229875
    [Abstract] [Full Text] [Related]

  • 7. Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands.
    Bajda M, Łażewska D, Godyń J, Zaręba P, Kuder K, Hagenow S, Łątka K, Stawarska E, Stark H, Kieć-Kononowicz K, Malawska B.
    Eur J Med Chem; 2020 Jan 01; 185():111785. PubMed ID: 31669851
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil-indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease.
    Bautista-Aguilera OM, Esteban G, Bolea I, Nikolic K, Agbaba D, Moraleda I, Iriepa I, Samadi A, Soriano E, Unzeta M, Marco-Contelles J.
    Eur J Med Chem; 2014 Mar 21; 75():82-95. PubMed ID: 24530494
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis, and evaluation of chalcone-Vitamin E-donepezil hybrids as multi-target-directed ligands for the treatment of Alzheimer's disease.
    Sang Z, Song Q, Cao Z, Deng Y, Zhang L.
    J Enzyme Inhib Med Chem; 2022 Dec 21; 37(1):69-85. PubMed ID: 34894968
    [Abstract] [Full Text] [Related]

  • 10. Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents.
    Pisani L, Farina R, Catto M, Iacobazzi RM, Nicolotti O, Cellamare S, Mangiatordi GF, Denora N, Soto-Otero R, Siragusa L, Altomare CD, Carotti A.
    J Med Chem; 2016 Jul 28; 59(14):6791-806. PubMed ID: 27347731
    [Abstract] [Full Text] [Related]

  • 11. Novel pyridazinone derivatives as butyrylcholinesterase inhibitors.
    Dundar Y, Kuyrukcu O, Eren G, Senol Deniz FS, Onkol T, Orhan IE.
    Bioorg Chem; 2019 Nov 28; 92():103304. PubMed ID: 31561108
    [Abstract] [Full Text] [Related]

  • 12. Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids.
    Bautista-Aguilera OM, Esteban G, Chioua M, Nikolic K, Agbaba D, Moraleda I, Iriepa I, Soriano E, Samadi A, Unzeta M, Marco-Contelles J.
    Drug Des Devel Ther; 2014 Nov 28; 8():1893-910. PubMed ID: 25378907
    [Abstract] [Full Text] [Related]

  • 13. Isoquinoline alkaloids from the roots of Zanthoxylum rigidum as multi-target inhibitors of cholinesterase, monoamine oxidase A and Aβ1-42 aggregation.
    Plazas E, Hagenow S, Avila Murillo M, Stark H, Cuca LE.
    Bioorg Chem; 2020 May 28; 98():103722. PubMed ID: 32155491
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis and biological evaluation of novel coumarin-N-benzyl pyridinium hybrids as multi-target agents for the treatment of Alzheimer's disease.
    Lan JS, Ding Y, Liu Y, Kang P, Hou JW, Zhang XY, Xie SS, Zhang T.
    Eur J Med Chem; 2017 Oct 20; 139():48-59. PubMed ID: 28797883
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease.
    Joubert J, Foka GB, Repsold BP, Oliver DW, Kapp E, Malan SF.
    Eur J Med Chem; 2017 Jan 05; 125():853-864. PubMed ID: 27744252
    [Abstract] [Full Text] [Related]

  • 16. Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine.
    Samadi A, de los Ríos C, Bolea I, Chioua M, Iriepa I, Moraleda I, Bartolini M, Andrisano V, Gálvez E, Valderas C, Unzeta M, Marco-Contelles J.
    Eur J Med Chem; 2012 Jun 05; 52():251-62. PubMed ID: 22503231
    [Abstract] [Full Text] [Related]

  • 17. Discovery of novel 3-butyl-6-benzyloxyphthalide Mannich base derivatives as multifunctional agents against Alzheimer's disease.
    Liu Z, Shi Y, Zhang X, Yu G, Li J, Cong S, Deng Y.
    Bioorg Med Chem; 2022 Mar 15; 58():116660. PubMed ID: 35183029
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis, and in vitro evaluation of 4-aminoalkyl-1(2H)-phthalazinones as potential multifunctional anti-Alzheimer's disease agents.
    Ye C, Xu R, Cao Z, Song Q, Yu G, Shi Y, Liu Z, Liu X, Deng Y.
    Bioorg Chem; 2021 Jun 15; 111():104895. PubMed ID: 33887586
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.
    Zhu J, Yang H, Chen Y, Lin H, Li Q, Mo J, Bian Y, Pei Y, Sun H.
    J Enzyme Inhib Med Chem; 2018 Dec 15; 33(1):496-506. PubMed ID: 29405075
    [Abstract] [Full Text] [Related]

  • 20. Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
    Bolea I, Juárez-Jiménez J, de Los Ríos C, Chioua M, Pouplana R, Luque FJ, Unzeta M, Marco-Contelles J, Samadi A.
    J Med Chem; 2011 Dec 22; 54(24):8251-70. PubMed ID: 22023459
    [Abstract] [Full Text] [Related]

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