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187 related items for PubMed ID: 34242699
1. 24-Norursodeoxycholic acid reshapes immunometabolism in CD8+ T cells and alleviates hepatic inflammation. Zhu C, Boucheron N, Müller AC, Májek P, Claudel T, Halilbasic E, Baazim H, Lercher A, Viczenczova C, Hainberger D, Preglej T, Sandner L, Alteneder M, Gülich AF, Khan M, Hamminger P, Remetic J, Ohradanova-Repic A, Schatzlmaier P, Donner C, Fuchs CD, Stojakovic T, Scharnagl H, Sakaguchi S, Weichhart T, Bergthaler A, Stockinger H, Ellmeier W, Trauner M. J Hepatol; 2021 Nov; 75(5):1164-1176. PubMed ID: 34242699 [Abstract] [Full Text] [Related]
2. norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis. Fickert P, Hirschfield GM, Denk G, Marschall HU, Altorjay I, Färkkilä M, Schramm C, Spengler U, Chapman R, Bergquist A, Schrumpf E, Nevens F, Trivedi P, Reiter FP, Tornai I, Halilbasic E, Greinwald R, Pröls M, Manns MP, Trauner M, European PSC norUDCA Study Group. J Hepatol; 2017 Sep; 67(3):549-558. PubMed ID: 28529147 [Abstract] [Full Text] [Related]
3. Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice. Halilbasic E, Fiorotto R, Fickert P, Marschall HU, Moustafa T, Spirli C, Fuchsbichler A, Gumhold J, Silbert D, Zatloukal K, Langner C, Maitra U, Denk H, Hofmann AF, Strazzabosco M, Trauner M. Hepatology; 2009 Jun; 49(6):1972-81. PubMed ID: 19475687 [Abstract] [Full Text] [Related]
4. 24-nor-ursodeoxycholic acid ameliorates inflammatory response and liver fibrosis in a murine model of hepatic schistosomiasis. Sombetzki M, Fuchs CD, Fickert P, Österreicher CH, Mueller M, Claudel T, Loebermann M, Engelmann R, Langner C, Sahin E, Schwinge D, Guenther ND, Schramm C, Mueller-Hilke B, Reisinger EC, Trauner M. J Hepatol; 2015 Apr; 62(4):871-8. PubMed ID: 25463533 [Abstract] [Full Text] [Related]
5. Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver. Denk GU, Maitz S, Wimmer R, Rust C, Invernizzi P, Ferdinandusse S, Kulik W, Fuchsbichler A, Fickert P, Trauner M, Hofmann AF, Beuers U. Hepatology; 2010 Nov; 52(5):1758-68. PubMed ID: 21038414 [Abstract] [Full Text] [Related]
6. Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis. Reich M, Spomer L, Klindt C, Fuchs K, Stindt J, Deutschmann K, Höhne J, Liaskou E, Hov JR, Karlsen TH, Beuers U, Verheij J, Ferreira-Gonzalez S, Hirschfield G, Forbes SJ, Schramm C, Esposito I, Nierhoff D, Fickert P, Fuchs CD, Trauner M, García-Beccaria M, Gabernet G, Nahnsen S, Mallm JP, Vogel M, Schoonjans K, Lautwein T, Köhrer K, Häussinger D, Luedde T, Heikenwalder M, Keitel V. J Hepatol; 2021 Sep; 75(3):634-646. PubMed ID: 33872692 [Abstract] [Full Text] [Related]
8. Nor-Ursodeoxycholic Acid as a Novel Therapeutic Approach for Cholestatic and Metabolic Liver Diseases. Halilbasic E, Steinacher D, Trauner M. Dig Dis; 2017 Sep; 35(3):288-292. PubMed ID: 28249255 [Abstract] [Full Text] [Related]
9. 24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Fickert P, Wagner M, Marschall HU, Fuchsbichler A, Zollner G, Tsybrovskyy O, Zatloukal K, Liu J, Waalkes MP, Cover C, Denk H, Hofmann AF, Jaeschke H, Trauner M. Gastroenterology; 2006 Feb; 130(2):465-81. PubMed ID: 16472600 [Abstract] [Full Text] [Related]
10. Characterization of ursodeoxycholic and norursodeoxycholic acid as substrates of the hepatic uptake transporters OATP1B1, OATP1B3, OATP2B1 and NTCP. König J, Klatt S, Dilger K, Fromm MF. Basic Clin Pharmacol Toxicol; 2012 Aug; 111(2):81-6. PubMed ID: 22333292 [Abstract] [Full Text] [Related]
11. NorUrsodeoxycholic acid ameliorates cholemic nephropathy in bile duct ligated mice. Krones E, Eller K, Pollheimer MJ, Racedo S, Kirsch AH, Frauscher B, Wahlström A, Ståhlman M, Trauner M, Grahammer F, Huber TB, Wagner K, Rosenkranz AR, Marschall HU, Fickert P. J Hepatol; 2017 Jul; 67(1):110-119. PubMed ID: 28242240 [Abstract] [Full Text] [Related]
12. Macrophages in cholangiopathies. Bruneau A, Guillot A, Tacke F. Curr Opin Gastroenterol; 2022 Mar 01; 38(2):114-120. PubMed ID: 35098932 [Abstract] [Full Text] [Related]
13. Influence of 24-Nor-Ursodeoxycholic Acid on Hepatic Disposition of [(18)F]Ciprofloxacin, a Positron Emission Tomography Study in Mice. Wanek T, Halilbasic E, Visentin M, Mairinger S, Römermann K, Stieger B, Kuntner C, Müller M, Langer O, Trauner M. J Pharm Sci; 2016 Jan 01; 105(1):106-12. PubMed ID: 26852845 [Abstract] [Full Text] [Related]
15. Nor-ursodeoxycholic acid reverses hepatocyte-specific nemo-dependent steatohepatitis. Beraza N, Ofner-Ziegenfuss L, Ehedego H, Boekschoten M, Bischoff SC, Mueller M, Trauner M, Trautwein C. Gut; 2011 Mar 01; 60(3):387-96. PubMed ID: 21115542 [Abstract] [Full Text] [Related]
16. Antagonistic effects of the cytotoxic molecules granzyme B and TRAIL in the immunopathogenesis of sclerosing cholangitis. Kellerer M, Javed S, Casar C, Will N, Berkhout LK, Schwinge D, Krebs CF, Schramm C, Neumann K, Tiegs G. Hepatology; 2024 Oct 01; 80(4):844-858. PubMed ID: 38441998 [Abstract] [Full Text] [Related]
17. Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury. Moustafa T, Fickert P, Magnes C, Guelly C, Thueringer A, Frank S, Kratky D, Sattler W, Reicher H, Sinner F, Gumhold J, Silbert D, Fauler G, Höfler G, Lass A, Zechner R, Trauner M. Gastroenterology; 2012 Jan 01; 142(1):140-151.e12. PubMed ID: 22001865 [Abstract] [Full Text] [Related]