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Journal Abstract Search

197 related items for PubMed ID: 34303749

  • 1. Identification and evaluation of potential SARS-CoV-2 antiviral agents targeting mRNA cap guanine N7-Methyltransferase.
    Kasprzyk R, Spiewla TJ, Smietanski M, Golojuch S, Vangeel L, De Jonghe S, Jochmans D, Neyts J, Kowalska J, Jemielity J.
    Antiviral Res; 2021 Sep; 193():105142. PubMed ID: 34303749
    [Abstract] [Full Text] [Related]

  • 2. Development of a High-Throughput Screening Assay to Identify Inhibitors of the SARS-CoV-2 Guanine-N7-Methyltransferase Using RapidFire Mass Spectrometry.
    Pearson LA, Green CJ, Lin D, Petit AP, Gray DW, Cowling VH, Fordyce EAF.
    SLAS Discov; 2021 Jul; 26(6):749-756. PubMed ID: 33724070
    [Abstract] [Full Text] [Related]

  • 3. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase.
    Basu S, Mak T, Ulferts R, Wu M, Deegan T, Fujisawa R, Tan KW, Lim CT, Basier C, Canal B, Curran JF, Drury LS, McClure AW, Roberts EL, Weissmann F, Zeisner TU, Beale R, Cowling VH, Howell M, Labib K, Diffley JFX.
    Biochem J; 2021 Jul 16; 478(13):2481-2497. PubMed ID: 34198328
    [Abstract] [Full Text] [Related]

  • 4. Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase.
    Ahmed-Belkacem R, Sutto-Ortiz P, Guiraud M, Canard B, Vasseur JJ, Decroly E, Debart F.
    Eur J Med Chem; 2020 Sep 01; 201():112557. PubMed ID: 32563813
    [Abstract] [Full Text] [Related]

  • 5. Label-Free Screening of SARS-CoV-2 NSP14 Exonuclease Activity Using SAMDI Mass Spectrometry.
    Scholle MD, Liu C, Deval J, Gurard-Levin ZA.
    SLAS Discov; 2021 Jul 01; 26(6):766-774. PubMed ID: 33870746
    [Abstract] [Full Text] [Related]

  • 6. Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19.
    Selvaraj C, Dinesh DC, Panwar U, Abhirami R, Boura E, Singh SK.
    J Biomol Struct Dyn; 2021 Aug 01; 39(13):4582-4593. PubMed ID: 32567979
    [Abstract] [Full Text] [Related]

  • 7. A High-Throughput RNA Displacement Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex toward Developing Therapeutics for COVID-19.
    Perveen S, Khalili Yazdi A, Devkota K, Li F, Ghiabi P, Hajian T, Loppnau P, Bolotokova A, Vedadi M.
    SLAS Discov; 2021 Jun 01; 26(5):620-627. PubMed ID: 33423577
    [Abstract] [Full Text] [Related]

  • 8. Potent Inhibition of SARS-CoV-2 nsp14 N7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues.
    Ahmed-Belkacem R, Hausdorff M, Delpal A, Sutto-Ortiz P, Colmant AMG, Touret F, Ogando NS, Snijder EJ, Canard B, Coutard B, Vasseur JJ, Decroly E, Debart F.
    J Med Chem; 2022 Apr 28; 65(8):6231-6249. PubMed ID: 35439007
    [Abstract] [Full Text] [Related]

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  • 12. Crystal structures and fragment screening of SARS-CoV-2 NSP14 reveal details of exoribonuclease activation and mRNA capping and provide starting points for antiviral drug development.
    Imprachim N, Yosaatmadja Y, Newman JA.
    Nucleic Acids Res; 2023 Jan 11; 51(1):475-487. PubMed ID: 36546776
    [Abstract] [Full Text] [Related]

  • 13. Structure-guided optimization of adenosine mimetics as selective and potent inhibitors of coronavirus nsp14 N7-methyltransferases.
    Hausdorff M, Delpal A, Barelier S, Nicollet L, Canard B, Touret F, Colmant A, Coutard B, Vasseur JJ, Decroly E, Debart F.
    Eur J Med Chem; 2023 Aug 05; 256():115474. PubMed ID: 37192550
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  • 14. Yeast-based assays for the high-throughput screening of inhibitors of coronavirus RNA cap guanine-N7-methyltransferase.
    Sun Y, Wang Z, Tao J, Wang Y, Wu A, Yang Z, Wang K, Shi L, Chen Y, Guo D.
    Antiviral Res; 2014 Apr 05; 104():156-64. PubMed ID: 24530452
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  • 16. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease.
    Canal B, McClure AW, Curran JF, Wu M, Ulferts R, Weissmann F, Zeng J, Bertolin AP, Milligan JC, Basu S, Drury LS, Deegan TD, Fujisawa R, Roberts EL, Basier C, Labib K, Beale R, Howell M, Diffley JFX.
    Biochem J; 2021 Jul 16; 478(13):2445-2464. PubMed ID: 34198326
    [Abstract] [Full Text] [Related]

  • 17. Synthetic Platforms for Characterizing and Targeting of SARS-CoV-2 Genome Capping Enzymes.
    Ornelas MY, Thomas AY, Johnson Rosas LI, Scoville RO, Mehta AP.
    ACS Synth Biol; 2022 Nov 18; 11(11):3759-3771. PubMed ID: 36331143
    [Abstract] [Full Text] [Related]

  • 18. Development of specific dengue virus 2'-O- and N7-methyltransferase assays for antiviral drug screening.
    Barral K, Sallamand C, Petzold C, Coutard B, Collet A, Thillier Y, Zimmermann J, Vasseur JJ, Canard B, Rohayem J, Debart F, Decroly E.
    Antiviral Res; 2013 Sep 18; 99(3):292-300. PubMed ID: 23769894
    [Abstract] [Full Text] [Related]

  • 19. Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals.
    Kottur J, White KM, Rodriguez ML, Rechkoblit O, Quintana-Feliciano R, Nayar A, García-Sastre A, Aggarwal AK.
    PLoS Pathog; 2023 Jul 18; 19(7):e1011546. PubMed ID: 37523415
    [Abstract] [Full Text] [Related]

  • 20. Characterization of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification.
    Baddock HT, Brolih S, Yosaatmadja Y, Ratnaweera M, Bielinski M, Swift LP, Cruz-Migoni A, Fan H, Keown JR, Walker AP, Morris GM, Grimes JM, Fodor E, Schofield CJ, Gileadi O, McHugh PJ.
    Nucleic Acids Res; 2022 Feb 22; 50(3):1484-1500. PubMed ID: 35037045
    [Abstract] [Full Text] [Related]

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