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Journal Abstract Search

329 related items for PubMed ID: 34360794

  • 1. Activation of Muscle-Specific Kinase (MuSK) Reduces Neuromuscular Defects in the Delta7 Mouse Model of Spinal Muscular Atrophy (SMA).
    Feng Z, Lam S, Tenn ES, Ghosh AS, Cantor S, Zhang W, Yen PF, Chen KS, Burden S, Paushkin S, Ayalon G, Ko CP.
    Int J Mol Sci; 2021 Jul 27; 22(15):. PubMed ID: 34360794
    [Abstract] [Full Text] [Related]

  • 2. Motor neuronal repletion of the NMJ organizer, Agrin, modulates the severity of the spinal muscular atrophy disease phenotype in model mice.
    Kim JK, Caine C, Awano T, Herbst R, Monani UR.
    Hum Mol Genet; 2017 Jul 01; 26(13):2377-2385. PubMed ID: 28379354
    [Abstract] [Full Text] [Related]

  • 3. Selective Neuromuscular Denervation in Taiwanese Severe SMA Mouse Can Be Reversed by Morpholino Antisense Oligonucleotides.
    Lin TL, Chen TH, Hsu YY, Cheng YH, Juang BT, Jong YJ.
    PLoS One; 2016 Jul 01; 11(4):e0154723. PubMed ID: 27124114
    [Abstract] [Full Text] [Related]

  • 4. At the "junction" of spinal muscular atrophy pathogenesis: the role of neuromuscular junction dysfunction in SMA disease progression.
    Goulet BB, Kothary R, Parks RJ.
    Curr Mol Med; 2013 Aug 01; 13(7):1160-74. PubMed ID: 23514457
    [Abstract] [Full Text] [Related]

  • 5. Motor transmission defects with sex differences in a new mouse model of mild spinal muscular atrophy.
    Deguise MO, De Repentigny Y, Tierney A, Beauvais A, Michaud J, Chehade L, Thabet M, Paul B, Reilly A, Gagnon S, Renaud JM, Kothary R.
    EBioMedicine; 2020 May 01; 55():102750. PubMed ID: 32339936
    [Abstract] [Full Text] [Related]

  • 6. A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology.
    Bowerman M, Murray LM, Beauvais A, Pinheiro B, Kothary R.
    Neuromuscul Disord; 2012 Mar 01; 22(3):263-76. PubMed ID: 22071333
    [Abstract] [Full Text] [Related]

  • 7. Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy.
    Ling KK, Gibbs RM, Feng Z, Ko CP.
    Hum Mol Genet; 2012 Jan 01; 21(1):185-95. PubMed ID: 21968514
    [Abstract] [Full Text] [Related]

  • 8. AAV9-DOK7 gene therapy reduces disease severity in Smn2B/- SMA model mice.
    Kaifer KA, Villalón E, Smith CE, Simon ME, Marquez J, Hopkins AE, Morcos TI, Lorson CL.
    Biochem Biophys Res Commun; 2020 Sep 10; 530(1):107-114. PubMed ID: 32828271
    [Abstract] [Full Text] [Related]

  • 9. Non-aggregating tau phosphorylation by cyclin-dependent kinase 5 contributes to motor neuron degeneration in spinal muscular atrophy.
    Miller N, Feng Z, Edens BM, Yang B, Shi H, Sze CC, Hong BT, Su SC, Cantu JA, Topczewski J, Crawford TO, Ko CP, Sumner CJ, Ma L, Ma YC.
    J Neurosci; 2015 Apr 15; 35(15):6038-50. PubMed ID: 25878277
    [Abstract] [Full Text] [Related]

  • 10. Survival motor neuron protein in motor neurons determines synaptic integrity in spinal muscular atrophy.
    Martinez TL, Kong L, Wang X, Osborne MA, Crowder ME, Van Meerbeke JP, Xu X, Davis C, Wooley J, Goldhamer DJ, Lutz CM, Rich MM, Sumner CJ.
    J Neurosci; 2012 Jun 20; 32(25):8703-15. PubMed ID: 22723710
    [Abstract] [Full Text] [Related]

  • 11. The MuSK activator agrin has a separate role essential for postnatal maintenance of neuromuscular synapses.
    Tezuka T, Inoue A, Hoshi T, Weatherbee SD, Burgess RW, Ueta R, Yamanashi Y.
    Proc Natl Acad Sci U S A; 2014 Nov 18; 111(46):16556-61. PubMed ID: 25368159
    [Abstract] [Full Text] [Related]

  • 12. Loganin possesses neuroprotective properties, restores SMN protein and activates protein synthesis positive regulator Akt/mTOR in experimental models of spinal muscular atrophy.
    Tseng YT, Chen CS, Jong YJ, Chang FR, Lo YC.
    Pharmacol Res; 2016 Sep 18; 111():58-75. PubMed ID: 27241020
    [Abstract] [Full Text] [Related]

  • 13. Cross-disease comparison of amyotrophic lateral sclerosis and spinal muscular atrophy reveals conservation of selective vulnerability but differential neuromuscular junction pathology.
    Comley LH, Nijssen J, Frost-Nylen J, Hedlund E.
    J Comp Neurol; 2016 May 01; 524(7):1424-42. PubMed ID: 26502195
    [Abstract] [Full Text] [Related]

  • 14. Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy.
    Kariya S, Park GH, Maeno-Hikichi Y, Leykekhman O, Lutz C, Arkovitz MS, Landmesser LT, Monani UR.
    Hum Mol Genet; 2008 Aug 15; 17(16):2552-69. PubMed ID: 18492800
    [Abstract] [Full Text] [Related]

  • 15. Localization and regulation of MuSK at the neuromuscular junction.
    Bowen DC, Park JS, Bodine S, Stark JL, Valenzuela DM, Stitt TN, Yancopoulos GD, Lindsay RM, Glass DJ, DiStefano PS.
    Dev Biol; 1998 Jul 15; 199(2):309-19. PubMed ID: 9698449
    [Abstract] [Full Text] [Related]

  • 16. Limited phenotypic effects of selectively augmenting the SMN protein in the neurons of a mouse model of severe spinal muscular atrophy.
    Lee AJ, Awano T, Park GH, Monani UR.
    PLoS One; 2012 Jul 15; 7(9):e46353. PubMed ID: 23029491
    [Abstract] [Full Text] [Related]

  • 17. Spinal motor neuron loss occurs through a p53-and-p21-independent mechanism in the Smn2B/- mouse model of spinal muscular atrophy.
    Reedich EJ, Kalski M, Armijo N, Cox GA, DiDonato CJ.
    Exp Neurol; 2021 Mar 15; 337():113587. PubMed ID: 33382987
    [Abstract] [Full Text] [Related]

  • 18. Defects in neuromuscular junction remodelling in the Smn(2B/-) mouse model of spinal muscular atrophy.
    Murray LM, Beauvais A, Bhanot K, Kothary R.
    Neurobiol Dis; 2013 Jan 15; 49():57-67. PubMed ID: 22960106
    [Abstract] [Full Text] [Related]

  • 19. Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy.
    Murray LM, Comley LH, Thomson D, Parkinson N, Talbot K, Gillingwater TH.
    Hum Mol Genet; 2008 Apr 01; 17(7):949-62. PubMed ID: 18065780
    [Abstract] [Full Text] [Related]

  • 20. A link between agrin signalling and Cav3.2 at the neuromuscular junction in spinal muscular atrophy.
    Delers P, Sapaly D, Salman B, De Waard S, De Waard M, Lefebvre S.
    Sci Rep; 2022 Nov 08; 12(1):18960. PubMed ID: 36347955
    [Abstract] [Full Text] [Related]

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