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1126 related items for PubMed ID: 34365057

  • 1. New thieno[3,2-d]pyrimidine-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents, EGFR and ARO inhibitors inducing apoptosis in breast cancer cells.
    Farghaly AM, AboulWafa OM, Baghdadi HH, Abd El Razik HA, Sedra SMY, Shamaa MM.
    Bioorg Chem; 2021 Oct; 115():105208. PubMed ID: 34365057
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  • 3. Design, Synthesis, biological Evaluation, and molecular docking studies of novel Pyrazolo[3,4-d]Pyrimidine derivative scaffolds as potent EGFR inhibitors and cell apoptosis inducers.
    Sherbiny FF, Bayoumi AH, El-Morsy AM, Sobhy M, Hagras M.
    Bioorg Chem; 2021 Nov; 116():105325. PubMed ID: 34507234
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  • 4. Design, synthesis and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as dual EGFR/HER2 inhibitors and apoptosis inducers.
    Elmetwally SA, Saied KF, Eissa IH, Elkaeed EB.
    Bioorg Chem; 2019 Jul; 88():102944. PubMed ID: 31051400
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  • 5. Discovery of new pyrimidine-5-carbonitrile derivatives as anticancer agents targeting EGFRWT and EGFRT790M.
    Nasser AA, Eissa IH, Oun MR, El-Zahabi MA, Taghour MS, Belal A, Saleh AM, Mehany ABM, Luesch H, Mostafa AE, Afifi WM, Rocca JR, Mahdy HA.
    Org Biomol Chem; 2020 Oct 07; 18(38):7608-7634. PubMed ID: 32959865
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  • 10. Design, synthesis and molecular docking study of new pyrimidine-based hydrazones with selective anti-proliferative activity against MCF-7 and MDA-MB-231 human breast cancer cell lines.
    Badawi WA, Samir M, Fathy HM, Okda TM, Noureldin MH, Atwa GMK, AboulWafa OM.
    Bioorg Chem; 2023 Sep 07; 138():106610. PubMed ID: 37210828
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  • 13. Design and Synthesis of Novel Quinazolinone-Based Oxobutanenitrile Derivatives as Antiproliferative Agents Targeting Human Breast Cancer.
    AboulWafa OM, Daabees HMGE, Ezz-ElDien ES.
    Anticancer Agents Med Chem; 2022 Sep 07; 22(12):2310-2326. PubMed ID: 34906060
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  • 14. Pyrazolo[3,4-d]pyrimidine-based dual EGFR T790M/HER2 inhibitors: Design, synthesis, structure-activity relationship and biological activity as potential antitumor and anticonvulsant agents.
    Lamie PF, El-Kalaawy AM, Abdel Latif NS, Rashed LA, Philoppes JN.
    Eur J Med Chem; 2021 Mar 15; 214():113222. PubMed ID: 33545637
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  • 15. Novel thienopyrimidine derivatives as dual EGFR and VEGFR-2 inhibitors: design, synthesis, anticancer activity and effect on cell cycle profile.
    Mghwary AE, Gedawy EM, Kamal AM, Abuel-Maaty SM.
    J Enzyme Inhib Med Chem; 2019 Dec 15; 34(1):838-852. PubMed ID: 30919701
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  • 16. Novel imidazolone derivatives as potential dual inhibitors of checkpoint kinases 1 and 2: Design, synthesis, cytotoxicity evaluation, and mechanistic insights.
    Sheta YS, Sarg MT, Abdulrahman FG, Nossier ES, Husseiny EM.
    Bioorg Chem; 2024 Aug 15; 149():107471. PubMed ID: 38823311
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  • 17. Design, Synthesis, In Silico and In Vitro Evaluation of Novel Pyrimidine Derivatives as EGFR Inhibitors.
    Matada GSP, Abbas N, Dhiwar PS, Basu R, Devasahayam G.
    Anticancer Agents Med Chem; 2021 Aug 15; 21(4):451-461. PubMed ID: 32698735
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  • 20. Synthesis and in vitro antitumor evaluation of new thieno[2,3-d]pyrimidine derivatives as EGFR and DHFR inhibitors.
    Fouad MM, Ghabbour HA, Shehata IA, El-Ashmawy MB.
    Bioorg Chem; 2024 Jul 15; 148():107401. PubMed ID: 38749115
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