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936 related items for PubMed ID: 34365904

  • 1. Live attenuated coronavirus vaccines deficient in N7-Methyltransferase activity induce both humoral and cellular immune responses in mice.
    Zhang Z, Liu Q, Sun Y, Li J, Liu J, Pan R, Cao L, Chen X, Li Y, Zhang Y, Xu K, Guo D, Zhou L, Lan K, Chen Y.
    Emerg Microbes Infect; 2021 Dec; 10(1):1626-1637. PubMed ID: 34365904
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  • 2. N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition.
    Pan R, Kindler E, Cao L, Zhou Y, Zhang Z, Liu Q, Ebert N, Züst R, Sun Y, Gorbalenya AE, Perlman S, Thiel V, Chen Y, Guo D.
    mBio; 2022 Feb 22; 13(1):e0366221. PubMed ID: 35073761
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  • 4. Porcine Epidemic Diarrhea Virus Deficient in RNA Cap Guanine-N-7 Methylation Is Attenuated and Induces Higher Type I and III Interferon Responses.
    Lu Y, Cai H, Lu M, Ma Y, Li A, Gao Y, Zhou J, Gu H, Li J, Gu J.
    J Virol; 2020 Jul 30; 94(16):. PubMed ID: 32461321
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  • 5. The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2.
    Ogando NS, Zevenhoven-Dobbe JC, van der Meer Y, Bredenbeek PJ, Posthuma CC, Snijder EJ.
    J Virol; 2020 Nov 09; 94(23):. PubMed ID: 32938769
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  • 7. Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines.
    Menachery VD, Gralinski LE, Mitchell HD, Dinnon KH, Leist SR, Yount BL, McAnarney ET, Graham RL, Waters KM, Baric RS.
    J Virol; 2018 Sep 01; 92(17):. PubMed ID: 29976657
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  • 10. Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication.
    Ogando NS, El Kazzi P, Zevenhoven-Dobbe JC, Bontes BW, Decombe A, Posthuma CC, Thiel V, Canard B, Ferron F, Decroly E, Snijder EJ.
    Proc Natl Acad Sci U S A; 2021 Dec 07; 118(49):. PubMed ID: 34845015
    [Abstract] [Full Text] [Related]

  • 11. Structure-function analysis of severe acute respiratory syndrome coronavirus RNA cap guanine-N7-methyltransferase.
    Chen Y, Tao J, Sun Y, Wu A, Su C, Gao G, Cai H, Qiu S, Wu Y, Ahola T, Guo D.
    J Virol; 2013 Jun 07; 87(11):6296-305. PubMed ID: 23536667
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  • 12. Synthetic Platforms for Characterizing and Targeting of SARS-CoV-2 Genome Capping Enzymes.
    Ornelas MY, Thomas AY, Johnson Rosas LI, Scoville RO, Mehta AP.
    ACS Synth Biol; 2022 Nov 18; 11(11):3759-3771. PubMed ID: 36331143
    [Abstract] [Full Text] [Related]

  • 13. Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase.
    Ahmed-Belkacem R, Sutto-Ortiz P, Guiraud M, Canard B, Vasseur JJ, Decroly E, Debart F.
    Eur J Med Chem; 2020 Sep 01; 201():112557. PubMed ID: 32563813
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  • 14. Translational shutdown and evasion of the innate immune response by SARS-CoV-2 NSP14 protein.
    Hsu JC, Laurent-Rolle M, Pawlak JB, Wilen CB, Cresswell P.
    Proc Natl Acad Sci U S A; 2021 Jun 15; 118(24):. PubMed ID: 34045361
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  • 15. A novel live attenuated duck Tembusu virus vaccine targeting N7 methyltransferase protects ducklings against pathogenic strains.
    Wu X, Huang S, Wang M, Chen S, Liu M, Zhu D, Zhao X, Wu Y, Yang Q, Zhang S, Huang J, Ou X, Zhang L, Liu Y, Yu Y, Gao Q, Mao S, Sun D, Tian B, Yin Z, Jing B, Cheng A, Jia R.
    Vet Res; 2023 Jun 12; 54(1):47. PubMed ID: 37308988
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  • 16. Coronavirus nsp10/nsp16 Methyltransferase Can Be Targeted by nsp10-Derived Peptide In Vitro and In Vivo To Reduce Replication and Pathogenesis.
    Wang Y, Sun Y, Wu A, Xu S, Pan R, Zeng C, Jin X, Ge X, Shi Z, Ahola T, Chen Y, Guo D.
    J Virol; 2015 Aug 12; 89(16):8416-27. PubMed ID: 26041293
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  • 17. Mutagenesis of Coronavirus nsp14 Reveals Its Potential Role in Modulation of the Innate Immune Response.
    Becares M, Pascual-Iglesias A, Nogales A, Sola I, Enjuanes L, Zuñiga S.
    J Virol; 2016 Jun 01; 90(11):5399-5414. PubMed ID: 27009949
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  • 18. Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis.
    Menachery VD, Gralinski LE, Mitchell HD, Dinnon KH, Leist SR, Yount BL, Graham RL, McAnarney ET, Stratton KG, Cockrell AS, Debbink K, Sims AC, Waters KM, Baric RS.
    mSphere; 2017 Jun 01; 2(6):. PubMed ID: 29152578
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  • 19. Generation of DelNS1 Influenza Viruses: a Strategy for Optimizing Live Attenuated Influenza Vaccines.
    Wang P, Zheng M, Lau SY, Chen P, Mok BW, Liu S, Liu H, Huang X, Cremin CJ, Song W, Chen Y, Wong YC, Huang H, To KK, Chen Z, Xia N, Yuen KY, Chen H.
    mBio; 2019 Sep 17; 10(5):. PubMed ID: 31530680
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  • 20. Characterization of the guanine-N7 methyltransferase activity of coronavirus nsp14 on nucleotide GTP.
    Jin X, Chen Y, Sun Y, Zeng C, Wang Y, Tao J, Wu A, Yu X, Zhang Z, Tian J, Guo D.
    Virus Res; 2013 Sep 17; 176(1-2):45-52. PubMed ID: 23702198
    [Abstract] [Full Text] [Related]

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