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140 related items for PubMed ID: 34448469

  • 1. Dexmedetomidine Exerts a Negative Chronotropic Action on Sinoatrial Node Cells Through the Activation of Imidazoline Receptors.
    Ishihara M, Kojima A, Ding WG, Kitagawa H, Matsuura H.
    J Cardiovasc Pharmacol; 2021 Dec 01; 78(6):826-838. PubMed ID: 34448469
    [Abstract] [Full Text] [Related]

  • 2. Direct negative chronotropic action of desflurane on sinoatrial node pacemaker activity in the guinea pig heart.
    Kojima A, Ito Y, Kitagawa H, Matsuura H, Nosaka S.
    Anesthesiology; 2014 Jun 01; 120(6):1400-13. PubMed ID: 24518231
    [Abstract] [Full Text] [Related]

  • 3. Ionic mechanisms underlying the negative chronotropic action of propofol on sinoatrial node automaticity in guinea pig heart.
    Kojima A, Ito Y, Kitagawa H, Matsuura H.
    Br J Pharmacol; 2015 Feb 01; 172(3):799-814. PubMed ID: 25220338
    [Abstract] [Full Text] [Related]

  • 4. Effectiveness in Block by Dexmedetomidine of Hyperpolarization-Activated Cation Current, Independent of Its Agonistic Effect on α2-Adrenergic Receptors.
    Lu TL, Lu TJ, Wu SN.
    Int J Mol Sci; 2020 Nov 30; 21(23):. PubMed ID: 33266068
    [Abstract] [Full Text] [Related]

  • 5. Ionic mechanisms of the action of anaesthetics on sinoatrial node automaticity.
    Kojima A, Matsuura H.
    Eur J Pharmacol; 2017 Nov 05; 814():63-72. PubMed ID: 28800884
    [Abstract] [Full Text] [Related]

  • 6. Pacemaker Channels and the Chronotropic Response in Health and Disease.
    Hennis K, Piantoni C, Biel M, Fenske S, Wahl-Schott C.
    Circ Res; 2024 May 10; 134(10):1348-1378. PubMed ID: 38723033
    [Abstract] [Full Text] [Related]

  • 7. The role of Ca2+ release from sarcoplasmic reticulum in the regulation of sinoatrial node automaticity.
    Hata T, Noda T, Nishimura M, Watanabe Y.
    Heart Vessels; 1996 May 10; 11(5):234-41. PubMed ID: 9129243
    [Abstract] [Full Text] [Related]

  • 8. Contribution of small conductance K+ channels to sinoatrial node pacemaker activity: insights from atrial-specific Na+ /Ca2+ exchange knockout mice.
    Torrente AG, Zhang R, Wang H, Zaini A, Kim B, Yue X, Philipson KD, Goldhaber JI.
    J Physiol; 2017 Jun 15; 595(12):3847-3865. PubMed ID: 28346695
    [Abstract] [Full Text] [Related]

  • 9. Negative chronotropic actions of endothelin-1 on rabbit sinoatrial node pacemaker cells.
    Tanaka H, Habuchi Y, Yamamoto T, Nishio M, Morikawa J, Yoshimura M.
    Br J Pharmacol; 1997 Sep 15; 122(2):321-9. PubMed ID: 9313942
    [Abstract] [Full Text] [Related]

  • 10. Dexmedetomidine relieves formaldehyde-induced pain in rats through both α2 adrenoceptor and imidazoline receptor.
    Zhang H, Yan X, Wang DG, Leng YF, Wan ZH, Liu YQ, Zhang Y.
    Biomed Pharmacother; 2017 Jun 15; 90():914-920. PubMed ID: 28441717
    [Abstract] [Full Text] [Related]

  • 11. Inhibitory effects of sevoflurane on pacemaking activity of sinoatrial node cells in guinea-pig heart.
    Kojima A, Kitagawa H, Omatsu-Kanbe M, Matsuura H, Nosaka S.
    Br J Pharmacol; 2012 Aug 15; 166(7):2117-35. PubMed ID: 22356456
    [Abstract] [Full Text] [Related]

  • 12. A rapidly activating delayed rectifier K+ current regulates pacemaker activity in adult mouse sinoatrial node cells.
    Clark RB, Mangoni ME, Lueger A, Couette B, Nargeot J, Giles WR.
    Am J Physiol Heart Circ Physiol; 2004 May 15; 286(5):H1757-66. PubMed ID: 14693686
    [Abstract] [Full Text] [Related]

  • 13. Dexmedetomidine, an alpha2-adrenergic agonist, inhibits neuronal delayed-rectifier potassium current and sodium current.
    Chen BS, Peng H, Wu SN.
    Br J Anaesth; 2009 Aug 15; 103(2):244-54. PubMed ID: 19542547
    [Abstract] [Full Text] [Related]

  • 14. Failure of Ba2+ and Cs+ to block the effects of vagal nerve stimulation in sinoatrial node cells of the guinea-pig heart.
    Bolter CP, Wallace DJ, Hirst GD.
    Auton Neurosci; 2001 Dec 10; 94(1-2):93-101. PubMed ID: 11775712
    [Abstract] [Full Text] [Related]

  • 15. The electrophysiological properties of spontaneously beating pacemaker cells isolated from mouse sinoatrial node.
    Cho HS, Takano M, Noma A.
    J Physiol; 2003 Jul 01; 550(Pt 1):169-80. PubMed ID: 12879867
    [Abstract] [Full Text] [Related]

  • 16. Imidazoline 1 receptor activation preserves respiratory drive in spontaneously breathing newborn rats during dexmedetomidine administration.
    Sato N, Saiki C, Tamiya J, Imai T, Sunada K.
    Paediatr Anaesth; 2017 May 01; 27(5):506-515. PubMed ID: 28177562
    [Abstract] [Full Text] [Related]

  • 17. Modulation of delayed rectifier potassium current, iK, by isoprenaline in rabbit isolated pacemaker cells.
    Lei M, Brown HF, Terrar DA.
    Exp Physiol; 2000 Jan 01; 85(1):27-35. PubMed ID: 10662889
    [Abstract] [Full Text] [Related]

  • 18. Molecular regulation and pharmacology of pacemaker channels.
    Bois P, Guinamard R, Chemaly AE, Faivre JF, Bescond J.
    Curr Pharm Des; 2007 Jan 01; 13(23):2338-49. PubMed ID: 17692005
    [Abstract] [Full Text] [Related]

  • 19. Ionic mechanisms underlying the positive chronotropy induced by beta1-adrenergic stimulation in guinea pig sinoatrial node cells: a simulation study.
    Himeno Y, Sarai N, Matsuoka S, Noma A.
    J Physiol Sci; 2008 Feb 01; 58(1):53-65. PubMed ID: 18201393
    [Abstract] [Full Text] [Related]

  • 20. Endothelin-1 inhibits pacemaker currents in rabbit SA node cells.
    Tanaka H, Habuchi Y, Nishio M, Yamamoto T, Suto F, Yoshimura M.
    J Cardiovasc Pharmacol; 1998 Feb 01; 31 Suppl 1():S440-2. PubMed ID: 9595507
    [Abstract] [Full Text] [Related]

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