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Journal Abstract Search

196 related items for PubMed ID: 34502040

  • 1. In Vitro and In Silico Evaluation of New 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]pyridazinone as Promising Cyclooxygenase Inhibitors.
    Peregrym K, Szczukowski Ł, Wiatrak B, Potyrak K, Czyżnikowska Ż, Świątek P.
    Int J Mol Sci; 2021 Aug 24; 22(17):. PubMed ID: 34502040
    [Abstract] [Full Text] [Related]

  • 2. Design, Synthesis and Comprehensive Investigations of Pyrrolo[3,4-d]pyridazinone-Based 1,3,4-Oxadiazole as New Class of Selective COX-2 Inhibitors.
    Szczukowski Ł, Krzyżak E, Zborowska A, Zając P, Potyrak K, Peregrym K, Wiatrak B, Marciniak A, Świątek P.
    Int J Mol Sci; 2020 Dec 17; 21(24):. PubMed ID: 33348757
    [Abstract] [Full Text] [Related]

  • 3. New N-Substituted-1,2,4-triazole Derivatives of Pyrrolo[3,4-d]pyridazinone with Significant Anti-Inflammatory Activity-Design, Synthesis and Complementary In Vitro, Computational and Spectroscopic Studies.
    Szczukowski Ł, Krzyżak E, Wiatrak B, Jawień P, Marciniak A, Kotynia A, Świątek P.
    Int J Mol Sci; 2021 Oct 18; 22(20):. PubMed ID: 34681894
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis, biological evaluation and in silico studies of novel pyrrolo[3,4-d]pyridazinone derivatives withpromising anti-inflammatory and antioxidant activity.
    Szczukowski Ł, Redzicka A, Wiatrak B, Krzyżak E, Marciniak A, Gębczak K, Gębarowski T, Świątek P.
    Bioorg Chem; 2020 Sep 18; 102():104035. PubMed ID: 32721780
    [Abstract] [Full Text] [Related]

  • 5. Synthesis, Biological, Spectroscopic and Computational Investigations of Novel N-Acylhydrazone Derivatives of Pyrrolo[3,4-d]pyridazinone as Dual COX/LOX Inhibitors.
    Mikus J, Świątek P, Przybyła P, Krzyżak E, Marciniak A, Kotynia A, Redzicka A, Wiatrak B, Jawień P, Gębarowski T, Szczukowski Ł.
    Molecules; 2023 Jul 18; 28(14):. PubMed ID: 37513351
    [Abstract] [Full Text] [Related]

  • 6. Synthesis, anti-inflammatory activity, and molecular docking studies of some novel Mannich bases of the 1,3,4-oxadiazole-2(3H)-thione scaffold.
    Ozyazici T, Gurdal EE, Orak D, Sipahi H, Ercetin T, Gulcan HO, Koksal M.
    Arch Pharm (Weinheim); 2020 Jul 18; 353(7):e2000061. PubMed ID: 32319141
    [Abstract] [Full Text] [Related]

  • 7. COX-1/COX-2 inhibition activities and molecular docking study of newly designed and synthesized pyrrolo[3,4-c]pyrrole Mannich bases.
    Redzicka A, Szczukowski Ł, Kochel A, Wiatrak B, Gębczak K, Czyżnikowska Ż.
    Bioorg Med Chem; 2019 Sep 01; 27(17):3918-3928. PubMed ID: 31345747
    [Abstract] [Full Text] [Related]

  • 8. New 1,3,4-Oxadiazole Derivatives of Pyridothiazine-1,1-Dioxide with Anti-Inflammatory Activity.
    Glomb T, Wiatrak B, Gębczak K, Gębarowski T, Bodetko D, Czyżnikowska Ż, Świątek P.
    Int J Mol Sci; 2020 Nov 30; 21(23):. PubMed ID: 33266208
    [Abstract] [Full Text] [Related]

  • 9. Synthesis, Cyclooxygenases Inhibition Activities and Interactions with BSA of N-substituted 1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones Derivatives.
    Krzyżak E, Szkatuła D, Wiatrak B, Gębarowski T, Marciniak A.
    Molecules; 2020 Jun 25; 25(12):. PubMed ID: 32630594
    [Abstract] [Full Text] [Related]

  • 10. Novel 1,3,4-oxadiazole/oxime hybrids: Synthesis, docking studies and investigation of anti-inflammatory, ulcerogenic liability and analgesic activities.
    Abd-Ellah HS, Abdel-Aziz M, Shoman ME, Beshr EA, Kaoud TS, Ahmed AF.
    Bioorg Chem; 2016 Dec 25; 69():48-63. PubMed ID: 27669120
    [Abstract] [Full Text] [Related]

  • 11. Synthesis, characterization, evaluation and molecular dynamics studies of 5, 6-diphenyl-1,2,4-triazin-3(2H)-one derivatives bearing 5-substituted 1,3,4-oxadiazole as potential anti-inflammatory and analgesic agents.
    Banerjee AG, Das N, Shengule SA, Srivastava RS, Shrivastava SK.
    Eur J Med Chem; 2015 Aug 28; 101():81-95. PubMed ID: 26117820
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and biological evaluation of 3,4-diphenyl-1,2,5-oxadiazole-2-oxides and 3,4-diphenyl-1,2,5-oxadiazoles as potential hybrid COX-2 inhibitor/nitric oxide donor agents.
    Velázquez C, Rao PN, McDonald R, Knaus EE.
    Bioorg Med Chem; 2005 Apr 15; 13(8):2749-57. PubMed ID: 15781386
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological evaluation as well as in silico studies of arylpiperazine-1,2-benzothiazine derivatives as novel anti-inflammatory agents.
    Szczęśniak-Sięga BM, Wiatrak B, Czyżnikowska Ż, Janczak J, Wiglusz RJ, Maniewska J.
    Bioorg Chem; 2021 Jan 15; 106():104476. PubMed ID: 33250206
    [Abstract] [Full Text] [Related]

  • 14. Docking Studies, Synthesis and Biological Evaluation of β-aryl-β-hydroxy Propanoic Acids for Anti-inflammatory Activity.
    Savic J, Dilber S, Milenkovic M, Kotur-Stevuljevic J, Markovic B, Vladimirov S, Brboric J.
    Med Chem; 2017 Jan 15; 13(2):186-195. PubMed ID: 27605092
    [Abstract] [Full Text] [Related]

  • 15. Biological Evaluation and Molecular Docking Studies of Novel 1,3,4-Oxadiazole Derivatives of 4,6-Dimethyl-2-sulfanylpyridine-3-carboxamide.
    Świątek P, Glomb T, Dobosz A, Gębarowski T, Wojtkowiak K, Jezierska A, Panek JJ, Świątek M, Strzelecka M.
    Int J Mol Sci; 2022 Jan 04; 23(1):. PubMed ID: 35008977
    [Abstract] [Full Text] [Related]

  • 16. Design and synthesis of benzimidazole analogs endowed with oxadiazole as selective COX-2 inhibitor.
    Rathore A, Rahman MU, Siddiqui AA, Ali A, Shaharyar M.
    Arch Pharm (Weinheim); 2014 Dec 04; 347(12):923-35. PubMed ID: 25303727
    [Abstract] [Full Text] [Related]

  • 17. Synthesis, pharmacological screening and in silico studies of new class of Diclofenac analogues as a promising anti-inflammatory agents.
    Palkar MB, Singhai AS, Ronad PM, Vishwanathswamy AH, Boreddy TS, Veerapur VP, Shaikh MS, Rane RA, Karpoormath R.
    Bioorg Med Chem; 2014 May 15; 22(10):2855-66. PubMed ID: 24751552
    [Abstract] [Full Text] [Related]

  • 18. Synthesis, molecular docking and biological evaluation of some newer 2-substituted-4-(benzo[d][1,3]dioxol-5-yl)-6-phenylpyridazin-3(2H)-ones as potential anti-inflammatory and analgesic agents.
    Singh J, Saini V, Kumar A, Bansal R.
    Bioorg Chem; 2017 Apr 15; 71():201-210. PubMed ID: 28236449
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, in vitro and in vivo biological evaluation, COX-1/2 inhibition and molecular docking study of indole-N-acylhydrazone derivatives.
    Moraes ADTO, Miranda MDS, Jacob ÍTT, Amorim CADC, Moura RO, Silva SÂSD, Soares MBP, Almeida SMV, Souza TRCL, Oliveira JF, Silva TGD, Melo CML, Moreira DRM, Lima MDCA.
    Bioorg Med Chem; 2018 Nov 01; 26(20):5388-5396. PubMed ID: 30293795
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and molecular docking of benzophenone conjugated with oxadiazole sulphur bridge pyrazole pharmacophores as anti inflammatory and analgesic agents.
    Zabiulla, Gulnaz AR, Mohammed YHE, Khanum SA.
    Bioorg Chem; 2019 Nov 01; 92():103220. PubMed ID: 31493708
    [Abstract] [Full Text] [Related]

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