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Journal Abstract Search

563 related items for PubMed ID: 34503586

  • 1. Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD mice.
    Delizannis AT, Nonneman A, Tsering W, De Bondt A, Van den Wyngaert I, Zhang B, Meymand E, Olufemi MF, Koivula P, Maimaiti S, Trojanowski JQ, Lee VM, Brunden KR.
    Acta Neuropathol Commun; 2021 Sep 09; 9(1):150. PubMed ID: 34503586
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  • 2. Microglial mTOR Activation Upregulates Trem2 and Enhances β-Amyloid Plaque Clearance in the 5XFAD Alzheimer's Disease Model.
    Shi Q, Chang C, Saliba A, Bhat MA.
    J Neurosci; 2022 Jul 06; 42(27):5294-5313. PubMed ID: 35672148
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  • 9. TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques.
    Wang Y, Ulland TK, Ulrich JD, Song W, Tzaferis JA, Hole JT, Yuan P, Mahan TE, Shi Y, Gilfillan S, Cella M, Grutzendler J, DeMattos RB, Cirrito JR, Holtzman DM, Colonna M.
    J Exp Med; 2016 May 02; 213(5):667-75. PubMed ID: 27091843
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  • 11. Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD mice.
    Zhao P, Xu Y, Fan X, Li L, Li X, Arase H, Tong Q, Zhang N, An Z.
    MAbs; 2022 May 02; 14(1):2107971. PubMed ID: 35921534
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  • 13. Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease.
    Boza-Serrano A, Ruiz R, Sanchez-Varo R, García-Revilla J, Yang Y, Jimenez-Ferrer I, Paulus A, Wennström M, Vilalta A, Allendorf D, Davila JC, Stegmayr J, Jiménez S, Roca-Ceballos MA, Navarro-Garrido V, Swanberg M, Hsieh CL, Real LM, Englund E, Linse S, Leffler H, Nilsson UJ, Brown GC, Gutierrez A, Vitorica J, Venero JL, Deierborg T.
    Acta Neuropathol; 2019 Aug 02; 138(2):251-273. PubMed ID: 31006066
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  • 17. THY-Tau22 mouse model accumulates more tauopathy at late stage of the disease in response to microglia deactivation through TREM2 deficiency.
    Vautheny A, Duwat C, Aurégan G, Joséphine C, Hérard AS, Jan C, Mitja J, Gipchtein P, Gaillard MC, Buée L, Blum D, Hantraye P, Bonvento G, Brouillet E, Cambon K, Bemelmans AP.
    Neurobiol Dis; 2021 Jul 02; 155():105398. PubMed ID: 34019997
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  • 18. Microglia Gravitate toward Amyloid Plaques Surrounded by Externalized Phosphatidylserine via TREM2.
    Park JC, Han JW, Lee W, Kim J, Lee SE, Lee D, Choi H, Han J, Kang YJ, Diep YN, Cho H, Kang R, Yu WJ, Lee J, Choi M, Im SW, Kim JI, Mook-Jung I.
    Adv Sci (Weinh); 2024 Sep 02; 11(34):e2400064. PubMed ID: 38981007
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  • 20. Identification of the minimal active soluble TREM2 sequence for modulating microglial phenotypes and amyloid pathology.
    Sheng X, Yao Y, Huang R, Xu Y, Zhu Y, Chen L, Zhang L, Wang W, Zhuo R, Can D, Chang CF, Zhang YW, Xu H, Bu G, Zhong L, Chen XF.
    J Neuroinflammation; 2021 Dec 10; 18(1):286. PubMed ID: 34893068
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